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Nutramax Denamarin Tablets for Large Dogs, 30 tablets

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Nutramax Denamarin Tablets for Large Dogs, 30 tablets

When liver function is compromised, the exact cause can often be difficult to determine. Supporting the liver, regardless of the cause, is essential to keep it working properly. Administering SAMe (S-Adenosylmethionine), which is found in Denamarin, has been shown to markedly increase liver levels of glutathione, an important compound for liver health formed when SAMe is metabolized. The SAMe in Denamarin has also been shown to help protect liver cells from cell death and may help cell repair and regeneration. Denamarin also helps support your pet’s liver through the administration of silybin. Silybin is an active part of an extract from milk thistle, known as silymarin, and has been shown to support liver function by helping maintain a healthy oxidative balance. 

While best known for supporting the liver in dogs, Denamarin also has a place in supporting brain health. Research is looking into dog aging and associated decreases in levels of S-Adenosylmethionine (SAMe) in cerebrospinal fluid, which surrounds the brain. Denamarin provides SAMe in a stabilized form to help with brain health and act as a neuroprotector. Denamarin also provides a bioavailable form of silybin which supports oxidative balance.

Key Benefits:

  • Increases glutathione, an important compound for liver health
  • Help protect liver cells from cell death
  • Help to repair and regenerate cells

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Item Number 73915
Country of Origin
  • United States
Breed Size
  • Large
Supplement Form
  • Tablet/Capsule
  • Adult

Contains 425 mg of S-Adenosylmethionine and 35 mg of silybin A+B

Body Weight
Body Weight
Number of Tablets Per Day
35-65 lbs 16-29.5 kg 1 tablet
66-120 lbs 30-54.5 kg 2 tablets
Over 120 lbs Over 54.5 kg 3 tablets

For optimal absorption, tablets should be given on an empty stomach, at least one hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. For those owners who have difficulty administering tablets to their pets, Denamarin tablet(s) may be disguised in a small bite of food. Studies have shown that, in many cases, tablets or capsules given as a “dry swallow” do not pass into the stomach in cats but may become lodged in the esophagus. It is recommended for pet owners to administer 3-6 cc of water immediately following any tablet administration to speed passage of the tablet into the stomach. If the pet is to receive more than one tablet daily, the total number of tablets may be divided between morning and evening for ease of administration. For example, a daily administration of three tablets could be divided into two tablets in the morning and one tablet in the evening.

Denamarin can be used in conjunction with Marin to provide additional silybin levels and the benefits of vitamin E and zinc supplementation. If Marin is used in conjunction with Denamarin, the two products should be administered 12 hours apart for best response.

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Nutramax Denamarin Tablets for Large Dogs Customer Reviews

Nutramax Denamarin Tablets for Large Dogs 5 5 15 15
This product contains the features we were looking for to help my lab's liver function. We have high hopes that Denamarin will help bring my 8 year old yellow lab's liver enzyme level down. She has been taking it 1 month and will have another liver test after the 3rd month. I love that this product is made here in the USA instead of overseas and then shipped here. The expiration date of all of the boxes I purchased is 2017 so I know the drug is very fresh. I am very pleased. February 26, 2014
Excellent product and service This is the first time ordering from this company on the recommendation from my vet. The service was excellent and boy were they fast. Received my order within 2 days delivered to my door. Saved me half of what the vet would have charged me. Will definitely order from this company again. April 15, 2014
product recommended by vet Denamarin seems to have helped my dog for elevated liver enzymes. have used this for 4 months and her blood tests have returned to normal levels. March 24, 2014
Great product and speedy delivery! This product was first introduced to us by our vet and has been very beneficial in our dog's health. It was great to find this product online at a reasonable cost, and the delivery was quicker than expected. Thank you! March 14, 2014
My dog swallows this pill easily, has no bitter taste, even though it is large. My dog swallows this pill easily, has no bitter taste, even though it is large. She generally does not like to take a pill, but I mix it with a small sausage and she accepts this without difficulty. March 17, 2014
Too Soon To Review It's too soon to review this product. It's an antoxidant for my 13 yo Lab who is on meloxicam for hip problems that has elevated liver enzymes. He was on Denosyl, which did NOT lower his #s, so our vet recommended trying Denamarin for the milk thistle ingredient. We won't know it it helps for a couple of months. March 17, 2014
Wonderful Product Denamarin is beginning to show signs of improvement in my dog. She acts more frisky and seems to be more alert since taking it. She’s been on it for slightly more than a month and has two more months before her next blood test. Everything seems to be going well … thank you,, for carrying this product! September 1, 2014
This is a great product for a dog with liver disease Have been giving this product to my Lab, who has liver disease, for about 2 years. It has made a big difference in the improvement of her health. August 27, 2014
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