21st Century Essential Pet Puppy Milk Replacer Powder for Puppies & Pregnant or Lactating Dogs, 12-oz

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Give your new pups exactly what they need with Puppy Milk Replacer Powder for Puppies & Pregnant or Lactating Dogs from 21st Century Essential Pet. It provides young pups with essential milk proteins along with vitamins, minerals and colostrum in an easy to use, shelf-stable powder form. This powder helps keep puppies as well as pregnant or lactating dogs healthy by providing essential amounts of protein, fat, carbohydrates and amino acids that newborn puppies need. Made with human-grade ingredients and flavor puppies love, 21st Century Essential Pet Puppy Milk Replacer Powder is here to support your furry loved one.

Key Benefits
  • Formulated for newborn puppies to 6 weeks of age, and to supplement lactating or pregnant dogs.
  • Provides pups with essential milk proteins along with vitamins and minerals.
  • Easy-to-use powder contains essential amounts of protein, fat, carbohydrates and amino acids.
  • Contains colostrum, which is a key source of large protein antibody molecules.
  • Made with human-grade ingredients in an FDA registered facility.

For Newborn Puppies to 6 weeks of age and Pregnant or Lactating Dogs. Not for human consumption. Individual results may vary. Warning: If Puppy develops diarrhea, does not gain weight, cries constantly, or becomes lethargic, take to a veterinarian. Reconstituted formula must be kept refrigerated for up to 24 hours. Opened powder must be refrigerated for up to 3 months or can be frozen for up to 6 months. Keep out of reach of children and animals. In case of accidental overdose, contact a health professional immediately.

See all items by 21st Century Essential Pet

  • Item Number
  • Weight
    12 ounces
  • Lifestage
  • Breed Size
    Small Breeds, Medium Breeds, Large Breeds, All Breeds
  • Food Form
  • Product Form
Nutritional Info

Animal & Vegetable Fat (Preserved with BHA and BHT), Dried Whey Protein Concentrate, Dried Whey, Sodium Caseinate, Dicalcium Phosphate, Dried Corn Syrup, L- Arginine, DL-Methionine, Spray Dried Egg Product, Calcium Carbonate, Lecithin, Potassium Sorbate, Calcium Chloride, Dried Colostrum, Choline Chloride, Magnesium Oxide, Iron Sulfate, Zinc Sulfate, Manganese Sulfate, Calcium Sulfate, Copper Sulfate, Sodium Selenite, Ethylenediamine Dihydroiodide, Cobalt Sulfate, DL-Alpha Tocopherol Acetate, Vitamin A Acetate, D-Activated Animal Sterol (source of Vitamin D3), Ascorbic Acid, Vitamin B12 Supplement, Riboflavin, Niacin Supplement, Calcium Pantothenate, Biotin, Folic Acid, Pyridoxine Hydrochloride, Thiamine Mononitrate, L-Lysine, Mono and Diglycerides of Edible Fats or Oils, Sodium Silico Aluminate, Artificial Flavor.

Caloric Content

5062(ME) kcal/kg dry powder, or 13 kcal/TBSP

Guaranteed Analysis
Crude Protein 33.0% min
Crude Fat 40.0% min
Crude Fiber 0.2% max
Moisture 5.0% max
Feeding Instructions

All puppies should receive their mother's milk for at least 2 days, if possible. This first milk gives extra nutrition and temporary immunity against some diseases. Warm reconstituted formula to room or body temperature (Do not use a microwave to warm reconstituted formula). Feed puppies 2 tablespoons of liquid (30 mL) per 4 oz. (115 g) of body weight. The daily feeding rate should be divided into equal portions for each feeding. The puppy's needs will vary and this amount may have to be increased or decreased, depending on the individual. Small or weak puppies may need to be fed every 3 to 4 hours, while larger and/or older puppies do well when fed formula every 8 hours. Weigh the puppies daily to assure adequate feeding. Individual results may vary. Consult your veterinarian for additional advice. Not for human consumption. When a food supplement is desired for growing post-weaned puppies, show dogs, supplementing large litters, and old, or convalescent dogs, powder should be fed at the rate of 1 teaspoon per 5 lbs. (2.3 kg) body weight.


Why should I include vitamins & supplements in my pet’s diet?

Most commercial pet foods include baseline vitamins and nutrients, but some may not have the adequate amount to suit your pet’s exact health needs. Like in humans, vitamins and supplements can help support your pet’s long-term health, regulating everything from digestion to muscle growth. Consult your veterinarian to determine the best vitamins and supplements for your furry friend.

How often should I give this supplement to my pet?

It is recommended to give the suggested dosage based off your pet’s weight. Please refer to the Feeding Instructions tab and consult with your veterinarian for more information.

Is this supplement safe to use with the medication my pet is currently taking?

If your pet has a medical condition and is taking other medication, we recommend consulting with your veterinarian to ensure that this supplement is safe to use.

My pet is allergic to certain ingredients, will this product be safe to use?

For a complete list of ingredients, click on the 'Nutritional Info' tab, next to the 'Description' tab, just under the product photos. If you are unsure about the safety of this product for your pet, we recommend consulting with your veterinarian.

Does this product come in other product forms?

For a complete assortment of products by the manufacturer of this supplement, click on the link next to the item name at the top of the page. You can also find an assortment of supplements across all product forms on our page.

Rating: 5.0 of 5 stars 3 Reviews 3 Reviews 5 out of 5 Stars

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  • 5 out of 5 stars

    I use this for my finicky dog

    By CinnamonSimone on Feb 24, 2021

    This product is a lifesaver. My dog has protein intolerance and cannot digest meat, or any dog food. She only eats vegetables. This product has Colostrum and helps with digestion and even allergies. My dog is a imperial shihtzu 3 years old and loves the 1/4 cup I give her daily. It helps supplement her vegetarian diet and gives her the nutrition that she needs. Would be good for a senior dog too (in my opinion. I'm not an expert).

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  • 5 out of 5 stars

    Just in time

    By Martha on Mar 28, 2020

    Just. In time Will be ordering again when we have puppies I enjoy getting my things from chewy wish I could get them faster but with the virus we are behind

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  • 5 out of 5 stars

    Mamá dog loves it

    By Aaaluuu1 on Sep 16, 2019

    I feed this too my female min pin so she can produce more milk I don't know if it works but the pups are not starving also bought as back up just in case

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