Acepromazine Injectable for Dogs, Cats & Horses, slide 1 of 1

Acepromazine Injectable for Dogs, Cats & Horses, 50-mL Multi-Dose vial

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Acepromazine Injectable is a rapid acting, 10mg/mL concentration injectable used as a preanesthetic and tranquilizer for dogs, cats and horses with a low order of toxicity. Can be used as an aid in controlling intractable animals during examination, treatment, grooming, x-ray and minor surgical procedures. Its rapid action and lack of hypnotic effect are added advantages.

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Dogs and Cats : Acepromazine Injection can be used as an aid in controlling intractable animals during examination, treatment, grooming, x-ray and minor surgical procedures; to alleviate itching as a result of skin irritation; as an antiemetic to control vomiting associated with motion sickness. Acepromazine Injection is particularly useful as a preanesthetic agent (1) to enhance and prolong the effects of barbiturates, thus reducing the requirements for general anesthesia; (2) as an adjunct to surgery under local anesthesia. Horses : Acepromazine Injection can be used as an aid in controlling fractious animals during examination, treatment, loading and transportation. Particularly useful when used in conjunction with local anesthesia for firing, castration, neurectomy, removal of skin tumors, ocular surgery and applying casts.

Possible Side Effects

Serious adverse reactions may occur such as behavioral disorders in dogs such as aggression, biting/chewing, and nervousness.

Drug & Food Interactions

Do not use Acepromazine Injection to control tremors associated with organic phosphate poisoning. Do not use in conjunction with organophosphorus vermifuges or ectoparasiticides, including flea collars. Do not use with procaine hydrochloride.


Tranquilizers, like Acepromazine Injectable, are potent central nervous system depressants and they can cause marked sedation with suppression of the sympathetic nervous system. Tranquilizers can produce prolonged depression or motor restlessness when given in excessive amounts or when given to sensitive animals. Tranquilizers are additive in action to the actions of other depressants and will potentiate general anesthesia. Tranquilizers should be administered in smaller doses and with greater care during general anesthesia and also to animals exhibiting symptoms of stress, debilitation, cardiac disease, sympathetic blockade, hypovolemia or shock. Acepromazine Injection, like other phenothiazine derivatives, is detoxified in the liver; therefore, it should be used with caution in animals with a previous history of liver dysfunction or leukopenia.

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  1. Prescribing Information

See all items by Acepromazine

  • Item Number
  • Generic Name
    Acepromazine Maleate
  • Common Brand Name(s)
    Acetylpromazine, PromAce
  • For Use With
    Dogs, Cats & Horses
  • Administration Form
  • Product Form
  • Health Condition
    Motion Sickness, Anxiety
  • Drug Type

Each mL contains: acepromazine maleate 10 mg, sodium citrate 0.36%, citric acid 0.075%, benzyl alcohol 1% and water for injection

Recommended Dosage

The dosage should be individualized, depending upon the degree of tranquilization required. As a general rule, the dosage requirement in mg/lb of body weight decreases as the weight of the animal increases. Dogs : 0.25-0.5 mg/lb of body weight Cats : 0.5-1 mg/lb of body weight Horses : 2-4 mg/100 lb of body weight

Storage Instructions

Store at 68° to 77°F, excursions permitted between 59° - 86°F. Use contents within 6 months of first puncture.


How is Acepromazine Injectable useful?

Acepromazine Injectable is most commonly used to sedate before surgery or stressful procedures.

How should I administer Acepromazine Injectable?

Acepromazine Injection may be given intravenously, intramuscularly or subcutaneously. IV doses should be administered slowly, and a period of at least 15 minutes should be allowed for the drug to take full effect.

Can handling this medication be hazardous to me, my family, or other animals?

There are no specific precautions required when handling this medication unless you are allergic to it. Wash your hands after handling any medication.

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