Adams Plus Flea & Tick Spot On for Large Dogs (31-60 lbs), 3 treatments

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Help protect your pup with Adams Plus Flea & Tick Spot On! This topical spot treatment is made in the USA for large dogs weighing between 31-60 pounds. Simply apply the quick-drying solution to your pet’s skin between the shoulder blades to help kill adult fleas, ticks (including those carrying Lyme disease), chewing lice and mosquitoes. This treatment, effective for 30 days, can also help break the life cycle of fleas and ticks by killing flea eggs, tick nymphs, and flea and tick larvae before they even hatch. Soon you’ll be able to enjoy all the snuggles from your sidekick without fear of pesky pests!

Key Benefits
  • Formulated to kill adult fleas, flea eggs, flea larvae, ticks, tick nymphs and tick larvae.
  • Helps kill and repel mosquitoes.
  • Each tube helps protect your pet from infestation for up to 30 days.
  • Dries quickly so your furry friend can get back to all the playing and petting.
  • Made in the USA.

Your pet may experience some temporary irritation at the site of application. If signs persist or become severe within a few days of application, consult your veterinarian immediately. Observe your pet following treatment. Sensitivities may occur after using ANY pesticide product on pets. Please read entire manufacturer’s insert prior to using product. Approved for use in breeding, pregnant, or nursing animals. Consult with veterinarian before using on sick, medicated or aged animals.

Important Information

Fleas rise to the top of your pet's coat as they die, so consider it a triumph if you start seeing more fleas at first, after treating your pet. If you’re still seeing fleas after application, it may be because your pet has picked up new fleas from the environment, which may include other pets, surfaces and outdoor areas. It may take up to 30 days to break the entire flea life cycle. Additionally, you should also treat sources of new fleas (i.e., carpet, yard, etc.) to ensure complete flea control.

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  • Item Number
  • Lifestage
    Adult, Puppy, Senior
  • Breed Size
    Medium Breeds, Large Breeds
  • Product Form

New: Active Ingredients: Etofenprox: 55.0%, Piperonyl Butoxide*: 10.0%, N-octyl Bicycloheptene Dicarboximide (MGK 264): 1.0%, Pyriproxyfen: 0.5%

New: Other Ingredients: 33.5%

Original: Active Ingredients: Etofenprox: 50.00%, Piperonyl Butoxide*: 9.10%, N-octyl Bicycloheptene Dicarboximide (MGK 264): 0.91%, Pyriproxyfen: 0.45%, (S)-Methoprene: 0.23%

Original: Other Ingredients: 39.31%


Adams Plus Flea & Tick Spot On for Dogs works by application directly to the dog’s/puppy’s skin, not to the hair. When applying, manually push aside dog’s/puppy’s hair to allow direct application to the skin.

Note: Each package contains tubes for 3 applications.

To apply the Adams Plus Flea & Tick Spot On for Dogs treatment, use one disposable liquid tube for each application.

  • Bend at perforation and tear off first tube.
  • Hold tube upright and snap tip back, away from face and body.
  • The dog/puppy should be standing for easy application. Apply Adams Plus Flea & Tick Spot On for Dogs evenly to four or five spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of the solution at any one spot that could cause some of the solution to run off the side of the dog/puppy.
  • Do not spread Adams Plus Flea & Tick Spot On for Dogs by hand over the dog/puppy. Although the dog’s/puppy’s skin and hair oils will distribute the application over the entire dog/puppy, brushing the dog/puppy 12-24 hours after application will help to distribute the material over the skin.
  • Discard empty tube as described in Storage and Disposal.

Where is this product sourced from?

We source all our products from manufacturer approved distributors or directly from the manufacturers. Chewy takes pride in ensuring that our furry friends’ wellbeing is always our top priority. We have worked hard to partner with all of the manufactures to deliver 100% authentic products

About Adams

Total Flea Control

Total Flea Control

Stopping fleas and ticks takes a multi-pronged approach, so Adams has a whole line of products to help prevent, treat and eliminate biting pests for good. From shampoos to spot treatments to yard sprays and more, they help you make and keep your pets and home bite-free.

Healthy and Happy Pets, the Adams Way


Adams helps keep your best friends healthy by providing lasting protection from harmful pests and breaking the cycle of reinfestation.


Treating the areas of your home where fleas, ticks and larvae like to hide will make life more pleasant for everyone in your household.


Sold by veterinarians since 1975, Adams products are a tried and trusted name in flea and tick control that you can rely on.

About Adams

Adams has been making flea and tick control solutions trusted and sold by vets for over 40 years. They offer a complete line of topicals, collars, sprays, shampoos and indoor and outdoor household treatments to handle all your pest prevention, treatment and eradication needs. For a healthy pet and a happy home, trust Adams for long-lasting protection!

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Rating: 3.0 of 5 stars 8 Reviews 8 Reviews 3 out of 5 Stars

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  • 5 out of 5 stars

    Adams is the Best!!

    By on

    I really love Adams Brand products. This was my first encounter with their spot on flea treatment and I have to say, Adams hasn't failed me yet. It is working wonderfully for my Pup. She doesn't respond well with Frontline or the Generic Frontline treatments, so I was skeptical that this would work. I am very impressed, and will continue to use this treatment in the future.

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  • 1 out of 5 stars

    Do Not Purchase

    By on

    Don’t waste your money if you value any of your furniture. This product is not “quick drying” at all. I applied it to both of my dogs around 9 AM and at 9 PM it is still leaving greasy stains on my couch. I’ve attempted to clean it from the fabric with no luck yet. I am very disappointed!

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  • 5 out of 5 stars

    Same ingredients as Bio Spot

    By on

    I used Bio Spot for 40 years on three different dogs and had great results. When Bio Spot was discontinued its product, I was unhappy, until Chewy told me about Adams. Bio Spot and Adams protect my, now, dog (Jax) very well and for about half the price of other similar products. I will use Adams from Chewys!

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  • 3 out of 5 stars


    By on

    This doesn't work well unfortunately. It works great for our cats, but not on our dog.

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  • 1 out of 5 stars

    Ineffective so far

    By on

    I treated my dog immediately after receiving this product, and treated the house as well. After two weeks, the fleas are still present. So far, this product has provided no relief at all.

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  • 3 out of 5 stars

    Worked somewhat!

    By on

    While we had TERRIBLE RESULTS with the kitten and small dog medicine, this one seemed to help our labrador. Not 100% but still pretty good.

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  • 5 out of 5 stars

    love my pets

    By on

    I trust Adams, and have used this brand many times. It seems to always work and the price is very reasonable.

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  • 1 out of 5 stars

    Doesn't work

    By on

    Worked for about a day and then my dog was covered in fleas again

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