Advanced Dog Enzymatic Stain Remover & Odor Eliminator Refill, 1-gal bottle -

Advanced Dog Enzymatic Stain Remover & Odor Eliminator Refill, 1-gal bottle

By Nature's Miracle
Rated 4.4831 out of 5 stars

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$35.05Chewy Price
$41.49Chewy Price
$33.30Autoship Price
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This Item - Advanced Dog Enzymatic Stain Remover & Odor Eliminator Refill, 1-gal bottle
Rated 4.4831 out of 5 stars
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About This Item


  • Tough on severe bio-based dog stains and odors.
  • Includes patented microbes that target the toughest dog odors.
  • A multi-surface cleaner that can be used on carpets, hard floors, furniture, fabrics and more.
  • This cleaner is designed to be safe for use around dogs.
  • Features a light, fresh scent.

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Learn More About Nature's Miracle From Our Team of Experts

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Cleaner UsageFabric, Hard SurfaceFurniture/Upholstery, Bedding, CarpetFabric, Hard Surface, Carpet, Furniture/UpholsteryFabric, Hard Surface, Carpet, Furniture/UpholsteryFurniture/Upholstery, Bedding, Carpet
LifestageAdult, PuppyAdult, PuppyAdult, PuppyAdult, PuppyAdult
Cleaner TypeDeodorizer, Stain RemoverDeodorizer, Stain RemoverStain Remover, DeodorizerDeodorizer, Stain RemoverDeodorizer, Stain Remover
Top IngredientsWater, Bio-Enzymatic Odor-Locking technology, Oxygen Boosters...Water, Isopropyl Alcohol, Surfactants...Water, Biological Blend, Nonionic Surfactant, Fragrance, Opacifier.
Packaging TypeBulk

Questions & Answers

21 Customer Questions

What’s the difference between the regular NM Enzymatic cleanser and the severe stain remover?
Answer by ChewyApr 15, 2020
This Stain & Odor Eliminator discourages re-soiling by removing the odor of the toughest dog messes.

Will this work on concrete floors?
Answer by ChewyOct 18, 2019
This stain and odor eliminator is suitable for hard floors like concrete, terrazzo, marble, natural stone, clay, ceramic tile, and brick.

Is this safe on hardwood floors?
Answer by ChewyOct 16, 2022
This stain remover and odor eliminator should not be used on untreated hardwood, leather, suede, silk or wool specialty fabrics.

Will this remove the salts that may be left over from an old urine accident?
Answer by ChewyOct 09, 2019
The enzymatic formula in this cleaner will help to remove salts and crystals that are left behind as urine dries.

ReviewsWrite a Review

Rated 4.4831 out of 5 stars
385 Reviews
Would recommend to a friend

385 Customer Reviews

Filter by reviews that mention

Rated 5 out of 5 stars
By CeeJay on Jan 6, 2023

If you live with dogs, you must have this on hand

I have used this product for years - puppies, adult dogs, senior dogs, healthy and ailing and I would not be without it. Accidents happen, and when they do, this product removes the evidence - no smell, no stain.

Rated 5 out of 5 stars
By QueenElf on Nov 22, 2022

Wonderful Cleaner

This works great to remove any stinky stain from your floors with just a spray or 2! I ordered the big refill bottle to continue to clean up after my messy furbabies! I recommend this cleaning product!

Rated 5 out of 5 stars
By Debbie on Nov 17, 2022

Pet stain remover

This product is perfect for cleaning up my senior dogs pet urine accidents.

Rated 5 out of 5 stars
By Elian on Jun 18, 2022

Cleans any pet odor!

I’ve used this on pretty much any dog odor you can think of and Guinea pig cages as well. If you leave it to soak like the package says to it will get up just about anything even if it is soaked in or hardened on and it really takes the stench out. I’ve been using this same cleaner for about 2 1/2 years now and have potty trained 2 puppies with it and have no complaints. Never knew there was a giant refill bottle until now so this makes my life even easier.

Rated 5 out of 5 stars
By Susan on Aug 22, 2022

Nature’s Miracle Advanced Enzymatic Eliminator

Wonderful product. Much improved over the regular stain and odor eliminator. Highly recommended.

Rated 5 out of 5 stars
By Becki on Jul 11, 2022

Works well.

Works well and leaves a nice scent that doesn’t overpower the room.

Rated 5 out of 5 stars
By RoxyMom on Oct 26, 2021

Great Product!

My dogs are potty trained to use either the pee pads or go outside but when one of them is sick and can’t help it, they’ll miss the pad and hit the hardwood floor. This product is terrific not only on hardwood but on fabric too. We don’t have wall to wall carpet but we do have area rugs and you can spray it right on the rug. It will not discolor but it will completely remove odor. You must saturate the stain and let it dry. Do not try to clean fabric with water and soap first, just blot the wet stain and remove as much as you can with power towels before spraying Nature’s Miracle. I don’t know why some people are saying it has a strong perfume odor. It doesn’t. It has a fresh, clean scent and it does not foam or get “soapy”. If that’s happening it’s probably from pervious rug shampooing without proper rinsing. Natures Miracle has no suds.

Rated 1 out of 5 stars
By BigDogOOPS on Oct 16, 2021

Strong odor

I am a big fan of Natures Miracle products. My family has had many furry friends for many years. This was a first time purchase for this particular product. I am not a fan of the smell of this particular one. The smell stayed around along time. I will give this one away and purchase a different one.

Rated 5 out of 5 stars
By Linda on Feb 1, 2022

Works great for pee stains and odors

This enzymatic cleaner works well. Use as directed, and remove stains AND odor.

Rated 5 out of 5 stars
By Puppy on Jan 14, 2022

Puppy messes

Helping with cleaning up messes. While potty training of 4 month old puppy during the winter.