Advantage Multi Topical Solution for Dogs, 3-9 lbs, (Green Box)
By Advantage Multi

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About This Item
Your furry friend must have a current heartworm test result on file with your veterinarian in order to be prescribed heartworm medication. Please visit your veterinarian to have this test performed annually to protect your four-legged friend. Advantage Multi for Dogs is a broad-spectrum topical solution prescribed by veterinarians to provide a convenient monthly application to help alleviate canine companions from symptoms caused by pesky parasites. This easy-to-use topical solution helps to treat circulating microfilariae in heartworm-positive canines, fights against adult fleas, treats and controls flea infestations, and sarcoptic mange, along with common intestinal parasites including roundworms, hookworms and whipworms—this medication may also prevent heartworm disease in some dogs.
Proudly sourced directly from the manufacturer or their approved distributor. Guaranteed genuine and backed by the manufacturer.
Specifications
Item Number | 146314 |
---|---|
Common Brand Name(s) | Advantage Multi, Cydectin, ProHeart |
Generic Name | Imidacloprid, Moxidectin |
For Use With | Dogs |
Administration Form | Topical |
Breed Size | Extra Small & Toy Breeds |
Product Form | Solution |
Strength | 40 mg Imidacloprid and 10 mg Moxidectin |
Health Condition | Heartworms, Fleas, Roundworms, Hookworms, Mange, Whipworms |
Drug Type | Parasiticide |
Uses
Advantage Multi for Dogs is indicated for the prevention of heartworm disease caused by Dirofilaria Immitis and the treatment of Dirofilaria Immitis circulating microfilariae in heartworm-positive dogs. Advantage Multi for Dogs kills adult fleas and is indicated for the treatment of flea infestations (Ctenocephalides felis). Advantage Multi for Dogs is indicated for the treatment and control of sarcoptic mange caused by Sarcoptes Scabiei Varcanis.
Possible Side Effects
Contact your veterinarian if your dog experiences localized pruritus, hematochezia, diarrhea, vomiting, lethargy, inappetence or pyoderma.
Drug & Food Interactions
In a well-controlled field study Advantage Multi for Dogs was used safely in dogs concomitantly receiving angiotensin-converting enzyme (ACE) inhibitors, anticonvulsants, antihistamines, antimicrobials, chondropprotectants, corticosteroids, immunotherapeutics, monoamine oxidase (MAO) inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), ophthalmic medications, sympathomimetics, synthetic estrogens, thyroid hormones, and urinary acidifiers.
Precautions
Do not dispense dose applicator tubes without complete safety and administration information. Use with caution in sick, debilitated, or underweight animals. The safety of Advantage Multi for Dogs has not been established in breeding, pregnant, or lactating dogs. The safe use of Advantage Multi for Dogs has not been established in puppies and dogs less than 7 weeks of age or less than 3 lbs. body weight. Prior to administration of Advantage Multi for Dogs, dogs should be tested for existing heartworm infection. At the discretion of the veterinarian, infected dogs should be treated with an adulticide to remove adult heartworms. The safety of Advantage Multi for Dogs has not been evaluated when administered on the same day as an adulticide. Advantage Multi for Dogs is not effective against adult Dirofilaria Immitis.
Ingredients
Active Ingredients: 40 mg Imidacloprid (10%), 10 mg Moxidectin (2.5%).
Recommended Dosage
The recommended minimum dose is 4.5 mg/lb (10 mg/kg) imidacloprid and 1.1 mg/lb (2.5 mg/kg) moxidectin, once a month, by topical administration.
Storage Instructions
Store at room temperature between 39° - 77°F.
Is Advantage Multi for Dogs waterproof?
Advantage Multi for Dogs prevents heartworm disease in dogs after a swim or bath, 60 and 90 minutes respectively after application.
How do I apply Advantage Multi for Dogs?
Do not apply to irritated skin.
- Remove one dose applicator tube from the package.
- While holding the tube in an upright position, remove the cap from the tube.
- Turn the cap over and push the other end of the cap onto the tip of the tube.
- Twist the cap to break the seal and then remove cap from the tube.
- The dog should be standing for application. Part the hair on the back of the dog between the shoulder blades until the skin is visible.
For dogs weighing 20 lbs. or less, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. For dogs weighing more than 20 lbs., place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Do not apply an amount of solution at any one location that could run off the side of the dog. Do not let this product get in your dog's mouth or eyes. Do not allow the dog to lick any of the application sites for 30 minutes.
How old does my dog have to be to use Advantage Multi for Dogs?
Advantage Multi for Dogs is for use on puppies at least 7 weeks old and weighing at least 3 pounds.
Does Advantage Multi for Dogs expire?
Advantage Multi for Dogs does have an expiration date that can be found on the bottom edge of the package. Advantage Multi for Dogs should not be used past its expiration date.
When can I bathe my dog after using Advantage Multi for Dogs?
We recommend bathing before applying product. The product can be applied once the pet is towel dried. Shampooing 90 minutes after treatment does not reduce the effectiveness of Advantage Multi for Dogs in the prevention of heartworm disease. Shampooing or water immersion 4 days after treatment does not reduce the effectiveness of Advantage Multi for Dogs in the treatment of flea infestations. However, shampooing as often as once weekly may reduce the effectiveness of the product against fleas. Please use a pet shampoo that is soap-free.
Can my dog go swimming after using Advantage Multi for Dogs?
Yes. A study showed that when dogs went swimming 60 minutes after application, Advantage Multi for Dogs still effectively prevented heartworm disease. A study also showed that swimming 4 days after treatment did not reduce the effectiveness of Advantage Multi for Dogs in the treatment of flea infestations.
When should I put Advantage Multi on my dog?
You should apply Advantage Multi for Dogs monthly (every 30 days), all year-round.
How does Advantage Multi for Dogs work to kill fleas?
Advantage Multi for Dogs is applied to the pet's skin. The active ingredient spreads over your dog's body to kill fleas through contact so they don't have to bite your dog to die.
What if I miss an Advantage Multi for Dogs heartworm treatment?
Life happens. If you forget or miss a dose, simply treat your dog immediately. Advantage Multi for Dogs is heartworm prevention that forgives if you forget. It kills immature heartworms that may already be in your dog and continues to prevent future infection by killing newly acquired baby worms throughout the month. After a single dose, if you forget and go more than 30 days in between treatments, just treat immediately and resume your monthly schedule.
Does Advantage Multi for Dogs kill ticks?
No. Advantage Multi for Dogs provides broad-spectrum protection against heartworms, fleas, roundworms, hookworms, whipworms and the skin parasite sarcoptic mange. If you are concerned about ticks, Bayer has effective products that treat and prevent tick infestations.
How often can I use Advantage Multi for Dogs?
Use monthly, year-round, to prevent heartworm disease; kill adult fleas; treat flea infestations; treat and control hookworms, roundworms and whipworms; and treat and control sarcoptic mange.

Dosage Chart
Color | Weight Range | Volume | Strength | Dosage | Product Page |
---|---|---|---|---|---|
Green | 3-9 lbs | 0.4 mL | 40 mg Imidacloprid & 10 mg Moxidectin | Apply each dose once a month | ✓-Click Here |
Teal | 9.1-20 lbs | 1.0 mL | 100 mg Imidacloprid & 25 mg Moxidectin | Apply each dose once a month | ✓-Click Here |
Red | 20.1-55 lbs | 2.5 mL | 250 mg Imidacloprid & 62.5 mg Moxidectin | Apply each dose once a month | ✓-Click Here |
Blue | 55.1-88 lbs | 4.0 mL | 400 mg Imidacloprid & 100 mg Moxidectin | Apply each dose once a month | ✓-Click Here |
Brown | 88.1-110 lbs | 5.0 mL | 500 mg Imidacloprid & 125 mg Moxidectin | Apply each dose once a month | ✓-Click Here |
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ReviewsWrite a Review
26 Customer Reviews
Advantage Multi
This item works well for our dog in the woodsy Tennessee area where we live. Although the price is overwhelming, it’s the same at my vet’s RX site. I want to give my business to Chewy because they’ve done really nice things for us and several friends. Thanks, Chewy!
Service that is almost unequal
Sammy's medication arrived promptly in 2 days. There sevice is excellent unless there is a tornado involved!!
Great price
Thought I might have to do with out giving my babies there heart worm after doing it for years , but with the price increase from our Vet. With four dogs the coast was getting so high . I got two after my baby sister passed from cancer and one from my daughter I never excepted to have . I promised my baby sis I would take care of them but at 75 I could not return to work and Chewy is letting me be able to afford them . Thanks Chewy
Good check on prescription fill
Thanks chewy for catching that I had online ordered the same box as before for my little dog, but the vet and y’all picked up that my little dog has gotten littler and so needed the smaller prescription box. Good catch for all, thanks
Always keeps my little 7 lb baby safe & protected!
Used this every mosquito season & it has always done a great job protecting my beautiful little toy poodle! Also, never any adverse side effects! When our vet stopped carrying this, I was so thankful to find it on chewy.com! Thank you so much!!!
Easy to use
My Bella will not take any kind of oral medication so this is the best way to protect her
Excellent topical for Fleas, Ticks, and Heartworm
This topical solution is wonderful for my little Chaweenie. Elly May has had no adverse problems and is very healthy.
Best I have found and easy...........
I have used this for over 9+ years on my dogs, it works good and I don't worry with trying to get them to chew a pill. It takes care of everything the little girls can get into outside and no fleas inside either. With our mosquito population, I don't have to worry with heartworms either, so going to continue to use it monthly on all three my dogs. Only draw back is the expense for multi dog households. But it's worth the peace of mind knowing they can run to their hearts content since I live in the country.
best price
Chewy has the best price, quick delivery and great customer service.
Chewy never disappoints
I’ve been dealing with Chewy for a long time and have never been disappointed. I would never consider getting our pet supplies anywhere else.