Prescription Topical Flea & Tick Treatment for Cats

Help keep biting pests off your furry friend with topical flea and tick medication. Chewy carries many types of topical flea medicine, topical tick medicine, and non-prescription topical flea and tick products, too. Most topicals are designed to kill both fleas and ticks and to provide continuous protection over several weeks.

Before you buy prescription cat topical flea & tick medication online at Chewy, be sure to research your different flea control options and talk to your vet. The best flea & tick medication will be easy to administer, suited to your cat’s lifestyle, and effective for the climate you live in, and topicals can be a great choice. Your vet can advise you on whether a prescription topical product, an oral product or a non-prescription flea and tick treatment would be best. If you have a very young cat, you should talk to your veterinarian about prescription topical flea & tick medicine for kittens and whether it might be a good choice for your furry friend.

If you choose a topical flea control medicine, using it is fairly easy: simply apply the solution to the skin on the back of your cat’s neck—so she can’t easily scratch or lick it off—and you’re done. Most prescription flea topicals for cats offer long-lasting pest deterrence that can last for a month or more and they’re usually water-resistant, too.

Many topicals also contain worm medicine, preventing and treating parasites like roundworms, hookworms and more. As an alternative to topicals, some cat parents like the idea of oral flea & tick medication, but they are only a good choice if your cat will eat chewable tablets or submit to being pilled. The Chewy pet pharmacy has many of the medicines your vet might prescribe for your pets, including flea & tick medication for dogs, prescription cat medicine and everything else you might need. Shop our great selection of topical flea and tick medication and get what you need to help your best friend live a pest-free life!

Frequently Asked Questions About Prescription Topical Flea & Tick Treatment for Cats

How do I get cat topical flea and tick medication prescriptions online at Chewy Pharmacy?

Get cat topical flea and tick medication prescriptions online at Chewy Pharmacy by visiting your vet and talking about different flea and tick control options. Your vet can recommend a product and issue a prescription for the right type and dose. Then, go to and add the prescribed product to your cart. At checkout, add your kitty’s info and vet contact information so Chewy can verify the prescription on your behalf. That’s all you need to do to order your prescription flea and tick medications from Chewy!

What prescription cat topical flea and tick treatment is best?

The best prescription topical flea and tick treatment will vary by the age, health, lifestyle and needs of your cat, so talk to your vet about your choices. Popular brands include Advantage, Revolution and Bravecto, but there are many others that may serve your situation well. You can read the customer reviews on our site to learn more about all the brands we carry.

What is the difference between over-the-counter and prescription topical flea and tick medication?

The difference between over-the-counter and prescription topical flea and tick medication is that you need a vet to prescribe the latter. The ingredients in prescription medications are more carefully controlled and regulated, so dosing can be more precise and possibly safer, too. Many prescription treatments are also more effective than over-the-counter products. Your vet can give you the most up-to-date information on what works well, and which ones might be best for your cat.

Where do I apply cat topical flea and tick medicine and what do I need to know?

Apply cat topical flea and tick medicine between the shoulder blades so your cat can’t lick or easily rub it off. Most topical medications provide protection for a month, not only killing fleas and ticks but repelling them, as well. Many are designed to break the flea lifecycle and prevent reinfestation by killing fleas at various stages of development. Some may also prevent flea and tick-borne diseases by killing pests before they can bite your cat, and still others protect against heartworms and intestinal worms, as well. Read up on the different products available and consult with your vet about which options are right for you.

How do I set up Autoship for my prescription cat topical flea and tick medicine?

To set up Autoship for your prescription topical flea and tick medicine, select the Autoship option at checkout and choose a delivery frequency. Once you set up Autoship, you can change or cancel it any time you want. You must have a valid prescription or remaining refills on file for Autoship pharmacy deliveries to occur. If we do not have a prescription, or if your prescription is expiring, one of our team members will reach out to your vet to obtain all the necessary information. Never run out of prescription topical flea and tick medicine again with Autoship from Chewy!