Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count

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About This Item

Details

  • Designed to support your furry friend’s liver with s-adenosylmethionine (SAMe) to help increase levels of the antioxidant glutathione, a liver detoxifying agent.
  • Uses silybin for better absorption than the standardized milk thistle extract.
  • Support your furry friend’s liver—it’s responsible for removing toxins, storing energy, aiding digestion, and supporting the immune system.
  • Nutramax Laboratories Veterinary Sciences has been providing supplements for more than 30 years.
  • Only high-quality ingredients are used to ensure your four-legged friend is receiving a safe supplement.

Ingredient Information

Feeding Instructions

Instructions

Learn More About Nutramax From Our Team of Experts

Questions & Answers

26 Customer Questions

Does Chewy carry Denamarin Advanced?

Originally posted and answered on chewy.com
Answer by Chewy • Dec 31, 2025
Denamarin Advanced is generally considered a veterinary-exclusive product and is available only through veterinarians.

Can the tablet be broken in half and both haves taken at the same time with small peanut butter on each half?

Originally posted and answered on chewy.com
Answer by Chewy • Dec 10, 2025
While these tablets are not scored, they may be broken in half and fed in a manner that works best for your pet.

Can I give this to my 15 lb cat, and if so, how much?

Originally posted and answered on chewy.com
Answer by Chewy • Jul 12, 2025
For cats over 12 pounds, 1 tablet should be given twice daily.

My girl takes denamarin, but it always came in a box, medium size canine dose. Why r they different in the bottle? Are they the same?

Originally posted and answered on chewy.com
Answer by Huey • Aug 17, 2025
Check the ingredients and the amount of milligrams in each. Please make sure that the former medicine that came in a box is the exact ones. There is an "improved" chewable tablet. Depending on the instructions of the Vet, make sure that you are giving your pet the exact medication, as well as dosage.
Reviews
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4.6
Rated 4.6 out of 5 stars
1611 Ratings
Terms & Conditions

624 Customer Reviews

Rated 5 out of 5 stars
By Amanda on Dec 31, 2025
Originally posted on chewy.com

Helped liver enzymes for our kitten with dry FIP

My daughter’s little guy Ravioli was diagnosed with dry FIP at one year old. Liver enzymes being off the charts was one of his concerns. This in conjunction with

My daughter’s little guy Ravioli was diagnosed with dry FIP at one year old. Liver enzymes being off the charts was one of his concerns. This in conjunction with vet prescribed antivirals, appetite stimulant, and sub-q fluids saved his life. At his 6 month post-diagnosis check up, everything was beautiful with liver enzymes still ever so slightly elevated. We’ve kept him on this medicine to help support his liver further and hope to be able to wean in another month or two. Grateful for this med and for chewy getting it to us promptly when we need it.

Rated 4 out of 5 stars
By Marie on Jan 15, 2026
Originally posted on chewy.com

Your Sphynx cat needs this

I’m a third time owner of a Sphynx cat. They have weak immune systems. When I stop giving my 3 year old this tablet her health declines. Only downside is the pill

I’m a third time owner of a Sphynx cat. They have weak immune systems. When I stop giving my 3 year old this tablet her health declines. Only downside is the pill is the size of an Advil. I suggest the ones in foil instead of the jar. They are light sensitive and the foil helps keep them potent They are pricy but they work. They were highly recommended by my veterinarian

Rated 3 out of 5 stars
By Tilly on Dec 20, 2025
Originally posted on chewy.com

Didn't improve my pup's ALT values and gives both pups diarrhea

My vet recommended trying this liver supplement to see if it might improve Tilly's liver values. I gave this supplement to both pups as supplements for 6 weeks

My vet recommended trying this liver supplement to see if it might improve Tilly's liver values. I gave this supplement to both pups as supplements for 6 weeks. Tilly just got her test results and her liver values continued to increase. It is possible that whatever medical condition that is causing the ALT values to go up cannot be improved with this supplement. My own concern with this supplement is that it causes both pups to have diarrhea. Recommend ordering a small quantity to see how your pups react to this supplement before buying larger quality. I originally bought 2 boxes and then more 2 bottles to have enough for Tilly's recent blood work. I have taken Lola off this supplements because her colon is so sensitive that she would get bloody stool along with diarrhea when on this supplement. I am waiting to hear from the vet if i should continue to keep Tilly on this supplement.

Rated 5 out of 5 stars
By gale on Dec 25, 2025
Originally posted on chewy.com

Coated Tablets NO BITTERNESS

Relatively easy to give to our Cat, Mr. Foot. I hold, husband puts in mouth, holds shut, blows on his face. Release him to eat treats. Same nightly routine 30 nights

Relatively easy to give to our Cat, Mr. Foot. I hold, husband puts in mouth, holds shut, blows on his face. Release him to eat treats. Same nightly routine 30 nights. No spitting tablet out, no drooling (thanks to coated tablet), tablet swallowed every night. Only blood test, 60 more days will determine effectiveness of Denamarin.

Rated 2 out of 5 stars
By Mocha on Nov 6, 2025
Originally posted on chewy.com

Dog refuses to eat it

This is supposed to be given on an empty stomach for full efficacy, but no matter how I try to hide the pill, she won't eat it. My dog is extremely food motivated--she

This is supposed to be given on an empty stomach for full efficacy, but no matter how I try to hide the pill, she won't eat it. My dog is extremely food motivated--she will eat anything and will tolerate most medications, but for whatever reason hates Denamarin. I have wrapped it in chicken, bread, banana puree, she will only eat the food substance around it and spit the pill back out. I have also tried forcing the pill down her throat with no success and I feel bad for scaring her like that :( no matter what my dog will not touch this stuff. Maybe yours will be different but I cannot vouch for the efficacy of Denamarin due to my dog's compliance issues.

Rated 5 out of 5 stars
By Julie on Dec 14, 2025
Originally posted on chewy.com

This prescription is to help my kitty be cat, Miss Lola

My veterinarian recommended this product to help Lola‘s liver enzymes for when she goes in next month for lab test, her liver enzymes have gone down. Pray for my

My veterinarian recommended this product to help Lola‘s liver enzymes for when she goes in next month for lab test, her liver enzymes have gone down. Pray for my little kitty cat, Miss Lola.

Rated 5 out of 5 stars
By Leah on Nov 15, 2025
Originally posted on chewy.com

I love this stuff!

My cats bloodwork shows how well this along with the antibiotics saved his life! Also was giving royal canine recovery food. See the bloodwork for yourself! Absolutely

My cats bloodwork shows how well this along with the antibiotics saved his life! Also was giving royal canine recovery food. See the bloodwork for yourself! Absolutely amazing!

Rated 5 out of 5 stars
By Joel on Dec 4, 2025
Originally posted on chewy.com

It is helping my Yorkie with her Liver Disease

My vet put my little yorkie on this supplement for her Liver Disease. I am see a difference in her poop. It is turning back brown instead of whiteish. It seems to

My vet put my little yorkie on this supplement for her Liver Disease. I am see a difference in her poop. It is turning back brown instead of whiteish. It seems to be woking.

Rated 3 out of 5 stars
By Jeffrey on Sep 17, 2025
Originally posted on chewy.com

Liver Supplement but R&D Inconclusive

My 5yr old dog had leptospirosis which is a disease from drinking dirty water. There is a vaccine for sport dogs who retrieve wild foul. My dog is a rescue who was

My 5yr old dog had leptospirosis which is a disease from drinking dirty water. There is a vaccine for sport dogs who retrieve wild foul. My dog is a rescue who was on the street drinking street water and eating garbage. Dog given strong antibiotics and this supplement. Dogs' liver numbers greatly improved and prevented liver damage. My Vet prescribed the Nutramax product. But the Internal Medicine Specialist we saw said the supplement may or may not help as research inconclusive. She suggested use 1 bottle, which I did.

Rated 5 out of 5 stars
By Cheryl on Nov 13, 2025
Originally posted on chewy.com

Improved with Denamarin

My dog was dx with a mass on her liver and her numbers were high, but due to age and small size, opted not to biopsies and such. Vet recommended Denamarin and liver

My dog was dx with a mass on her liver and her numbers were high, but due to age and small size, opted not to biopsies and such. Vet recommended Denamarin and liver numbers have improved in 6 months time!