Nutramax Denamarin with S-Adenosylmethionine & Silybin Chewable Tablets Liver Supplement for Dogs, 30 count

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About This Item

Details

  • Only high-quality ingredients are used to ensure your four-legged friend is receiving a safe supplement.
  • Designed to support your pup’s liver with s-adenosylmethionine (SAMe) to help increase levels of the antioxidant glutathione, a liver detoxifying agent.
  • Uses silybin for better absorption than the standardized milk thistle extract.
  • Support your furry friend’s liver—it’s responsible for removing toxins, storing energy, aiding digestion, and supporting the immune system.
  • Nutramax Laboratories Veterinary Sciences has been providing supplements for more than 30 years.

Ingredient Information

Feeding Instructions

Instructions

Learn More About Nutramax From Our Team of Experts

Questions & Answers

20 Customer Questions

Can I give this 4 hours after a meal instead of 1 hour before a meal?

Originally posted and answered on chewy.com
Answer by Chewy • Oct 25, 2025
The supplement should be given on an empty stomach, at least one hour before a meal for optimal absorption. Four hours before a meal would work.

What's the difference between the coated and the chewable tablets?

Originally posted and answered on chewy.com
Answer by Chewy • Sep 24, 2025
Both the coated and the chewable tablets contain the same combination of S-Adenosylmethionine (SAMe) and Silybin-Phosphatidylcholine Complex (SPC). However, the coated tablets, which come in three sizes and are unflavored should be given whole, while the hydrolyzed chicken flavored chewable tablets, which come in one size, can be split for individual administration.

Can these pills be broken in half?

Originally posted and answered on chewy.com
Answer by Chewy • Apr 17, 2025
These tablets have a score in the middle so that it's easy to cut in half.

Can cats take this?

Originally posted and answered on chewy.com
Answer by Chewy • Jan 20, 2025
This supplement should be given by pet weight and is formulated specifically for dogs. Denamarin Liver Tablets for Cats are available directly on our site and have feeding instructions suitable for felines.
Reviews
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4.1
Rated 4.1 out of 5 stars
1563 Ratings
Terms & Conditions

882 Customer Reviews

Rated 5 out of 5 stars
By Barbara on Jan 23, 2026
Originally posted on chewy.com

Easy chewable

This chewable version is so much easier to use than the other type of pill (capsule). Buried in Braunschweiger it becomes a treat (it is bitter so needs something

This chewable version is so much easier to use than the other type of pill (capsule). Buried in Braunschweiger it becomes a treat (it is bitter so needs something to disguise the taste according to the package - they suggest liver paste). Needs taken on an empty stomach - an hour before a meal or 2 hours after according to package.

Rated 1 out of 5 stars
By Jennifer on Dec 29, 2025
Originally posted on chewy.com

Too big, do not recommend

These pills are marketed as chewables but for a picky dog who won’t take pills, they aren’t appetizing enough to be chewed. Very large, crumbly, no scent though

These pills are marketed as chewables but for a picky dog who won’t take pills, they aren’t appetizing enough to be chewed. Very large, crumbly, no scent though apparently they are liver- flavored. I’m better off with the regular pills and trying to mask it in a small amount of food for the amount of effort it takes to try to get these monsters down.

Rated 3 out of 5 stars
By Diane on Jan 19, 2026
Originally posted on chewy.com

Denamarin

They seem soft. They break when cutting. They don't have a moisture pack in them. Not sure the other bottle did but I didn't have trouble cutting them from the

They seem soft. They break when cutting. They don't have a moisture pack in them. Not sure the other bottle did but I didn't have trouble cutting them from the last bottle.

Rated 1 out of 5 stars
By tamara on Jan 31, 2026
Originally posted on chewy.com

He would not ingest it.

I cut this in quarters for my small dog and he just sniffed at it. I tried adding it to his food and when he ate it he threw up

I cut this in quarters for my small dog and he just sniffed at it. I tried adding it to his food and when he ate it he threw up

Rated 5 out of 5 stars
By Barbara on Nov 18, 2025
Originally posted on chewy.com

Great for dogs with liver issues

My dog has taken a variety of medications, including steroids, for several years due to an autoimmune disease and has high liver numbers. My vet specialist suggested

My dog has taken a variety of medications, including steroids, for several years due to an autoimmune disease and has high liver numbers. My vet specialist suggested giving her Denamarin. She’s doing very well and the vet credits Denamarin as contributing to her health.

Rated 1 out of 5 stars
By HELEN on Dec 2, 2025
Originally posted on chewy.com

It was a chewable version of the pill,

The dog would not take the pill even when masked with meats or cheese, now the dog will not chew the hard tablet. Have to chop it and put it in the kibble. Not really

The dog would not take the pill even when masked with meats or cheese, now the dog will not chew the hard tablet. Have to chop it and put it in the kibble. Not really worth the effort.

Rated 1 out of 5 stars
By S on Nov 24, 2025
Originally posted on chewy.com

Won’t buy again

It’s not Chewys fault- but this is a very large chalky tablet and our dog is supposed to take 2 on an empty stomach- they are hard to break down and ultimately we

It’s not Chewys fault- but this is a very large chalky tablet and our dog is supposed to take 2 on an empty stomach- they are hard to break down and ultimately we had to stop using them

Rated 5 out of 5 stars
By Janet on Oct 19, 2025
Originally posted on chewy.com

Lowered my dog's liver numbers.

My dog's liver enzymes were high and taking this brought her numbers down dramatically. She didn't like the taste. So I crushed the pill and mixed it with a small

My dog's liver enzymes were high and taking this brought her numbers down dramatically. She didn't like the taste. So I crushed the pill and mixed it with a small amount of wet cat food. It's hard to give my dog pills because she smells the medication and refuses to take it regardless of what I put the pill in. I felt like I was running out of ways to give her meds. Wet cat food works great! I know the bottle says to give on an empty stomach, but it still brought her numbers down. And it was my vet who used the word "dramatically."

Rated 1 out of 5 stars
By Jaime on Oct 6, 2025
Originally posted on chewy.com

Big Hard Round

this says chewable and it is nowhere near that! I have to crush it and try to figure out a way to give it to my dog but the problem is it says to give it without

this says chewable and it is nowhere near that! I have to crush it and try to figure out a way to give it to my dog but the problem is it says to give it without food. it is not chewable it is bigger than the normal pill. VERY VERY DISAPPOINTED And will never buy again! Don’t be fooled by the “chewable” lie!

Rated 5 out of 5 stars
By Rob on Dec 4, 2025
Originally posted on chewy.com

Works

My Maltipoo Milo is 13, has been on this for years, because he takes phenobarbital and keppra. Seems to keep his levels even....

My Maltipoo Milo is 13, has been on this for years, because he takes phenobarbital and keppra. Seems to keep his levels even....