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Bio Spot Active Care Flea & Tick Spot On Refill for Cats (3-Month Supply), 5-lbs & over

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Bio Spot Active Care Flea & Tick Spot On for Cats ensures continuing long-term protection for your pet. It kills fleas, flea eggs and deer ticks for up to 1 month. It also kills and repels mosquitoes that may transmit heartworm disease. Two sizes are available to fit your cat’s needs. 

Key Benefits

  • Intended to be used with the Bio Spot Smart Shield Applicator
  • For use on cats and kittens 12 weeks of age or older that are under 5 pounds
  • Kills fleas, flea eggs, flea larvae and deer ticks for up to 1 month. Also kills mosquitoes that may transmit heartworm disease
  • Contains a coat conditioner for a non-sticky application
  • Formulated with an Insect Growth Regulator (IGR) to break the flea-life cycle


Do not apply more than once every month. Do not use more than one tube per cat. Do not use on kittens less than 12 weeks old. Do not get this product in your cat's eyes or mouth. Do not allow your cat to ingest this product.

Active Ingredients

  • (S)-Methoprene 3.6%
  • Etofenprox 40.0%

See all items by Bio Spot

  • Item Number
  • Lifestage
    Kitten, Adult


  • OPEN: Use finger scoop to lift open pink door.
  • LOAD: To load, place tube white side up under the pink tabs.
  • CLOSE: Close the pink door and the tube will snap open.
  • APPLY: The cat/kitten should be standing for easy application. To apply, use tip to part hair and get next to the skin at the base of the skull. Press square on pink door and squeeze out the entire contents of the tube onto the skin. Do not spread Bio Spot Active Care by hand. Do not bathe the cat/kitten within the first 24 hours after Spot On has been applied. Households with more than one cat/kitten should prevent cats/kittens from grooming each other until solution has dried. Although the skin and hair oils will over time distribute the application over the entire cat/kitten, brushing the cat/kitten 12-24 hours after treatment will help to distribute the material over the skin.
  • DISPOSE: To dispose of empty tube, open pink door and drop empty tube into trash or offer for recycling if available. Close applicator device door and store in original package.
  • RETREAT: Do not reapply product for 30 days. Do not treat more than once per month.

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Customer Reviews

Bio Spot Active Care Flea & Tick Spot On Refill for Cats (3-Month Supply) is rated 3.9 out of 5 by 7.
Rated 5 out of 5 by from Love this product! Now that I have found this excelent product for my cats they will not go without again. Their coats are revived and not a flea in sight. This is a great product!
Date published: 2013-12-19
Rated 5 out of 5 by from This product works excellent - I swear to God!!!! I have been using this product for two years now for the stray cats that are now living in my home. Its cheaper and better than the other stuff!! Just reordered more - The price is great and you will never see ticks or fleas or ear mites again!! They will all die and never come back - I have 40 acres of woods and deer behind my house - God bless the people who make this stuff. Amen!!
Date published: 2014-11-29
Rated 1 out of 5 by from Both cats still have fleas almost a week later I was hoping for a cheaper alternative to the high priced topical flea stuff. I applied it to both of my cats who had fleas and almost a week later both cats are still scratching and I can still visibly see tons of fleas running around on them. It said fleas would start dying in 15 min. that's an understatement for sure! This product has had no effect on killing fleas whatsoever after 6 days!!! From now on I will definitely spend the extra bucks on Frontline or Advantage 2!!!!
Date published: 2016-04-17
Rated 5 out of 5 by from Works great on my cats, does not cause sensitivities on any of their skin. I really like this product and will continue using it. Couldn't ask for a better all round company for my Furbabies
Date published: 2016-10-28
Rated 1 out of 5 by from Dont waste your money. This stuff does not work. Fleas thrive after application. I bought this for my dog and cat and what a waste of time and money. Do yourself a favor and buy a better brand not this .
Date published: 2015-03-03
Rated 5 out of 5 by from Excellent price and it works! Been using this product on a 12 yr old small cat and a 2 yr old large cat. I buy the 3 to 6 months depending on what I can afford, I live right on the bay and it kills sand fleas as well. Great price quick delivery, and it works! Period! I have been buying for several years.
Date published: 2016-03-21
Rated 5 out of 5 by from Great Product I have two small cats. I put Bio Spot Active Care on them first of December So far so good. My cats are small so I think I could have shared a tube with them.
Date published: 2015-12-13
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