COCO AND LUNA SAMe Premium Salmon Flavor Powder Dog & Cat Supplement, 4-oz jar -

Coco and Luna SAMe Premium Salmon Flavor Powder Dog & Cat Supplement, 4-oz jar

By Coco and Luna
Rated 3.875 out of 5 stars
$34.90Chewy Price
$33.16Autoship Price
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About This Item


  • Supports mental and cognitive health in dogs and cats.
  • Choline and inositol promote brain health.
  • Supports liver health by protecting the liver from damage and supporting metabolic activity and cell regeneration.
  • Just mix the powder into your pet’s food daily for easy feeding.
  • Made in the USA.

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Nutritional Information

Feeding Instructions

Play Video: Learn More About Coco and Luna From Our Team of Experts
Learn More About Coco and Luna From Our Team of Experts

Questions & Answers

6 Customer Questions

What's the best way to give a powdered medicine to a dog without food? 🙄

Can you please tell me what size the scoop is exactly that comes in this product (in teaspoons or CC). I need to know exactly how much the included scoop holds exactly.
Answer by ChewyFeb 17, 2021
The scoop size for this product is a 1gram scoop, which is similar to a teaspoon.

How many scoops worth are in a jar?
Answer by ChewyMar 09, 2023
Each scoop weighs about 1 gram. The 4 ounce jar contains approximately 113 scoops.

List of ingredients
Answer by ChewyJan 10, 2022
For a complete list of ingredients, click the “Nutritional Info” tab, next to the “Description” tab, just under the product photos when viewed on a desk top. Click the "Nutritional Info" tab, next to the "Q&A" tab, towards the top bar above the product image when viewed on the app.

ReviewsWrite a Review

Rated 3.875 out of 5 stars
8 Ratings
Would recommend to a friend

8 Customer Reviews

Rated 2 out of 5 stars
By Meekah on Jul 27, 2022

Our old guy just doesn’t like it

Our 15 y/o chihuahua can detect it in his food. He’s always been too good at finding pills etc. But I know this has worked great for other families!

Rated 3 out of 5 stars
By Pepe on Apr 17, 2022

Good product but not in powder form

I think the powder with SamE supplement is doing its job but I was hoping that because it was powder it would be easy to just sprinkle on Pepe’s breakfast. The label still says give one hour before meal on empty stomach.

Rated 5 out of 5 stars
By Pluta on Nov 18, 2021

Freckles got a new bounce!

I gave this to my Freckles and while it didn’t help him so much cognitively, it really helped his joints! It’s a powder you dissolve. It says give on an empty stomach so it’s hard to find something to mix it with. I mixed it with a little bit of whip cream or yogurt. That usually worked. I have to put Freckles down tomorrow but this supplement gave him several months with much less pain!

Rated 2 out of 5 stars
By Heather on Oct 30, 2021


We got this supplement because the one we normally ordered was out of stock. The ingredients were the same except the supplement recommendations give your dog 1/3 the amount of SAM-e that the other supplements give and what our vet recommends. So what we thought was a month supply ended up being a 10 day supply for our large dog.

Rated 5 out of 5 stars
By Laura on Jun 21, 2021

Good Rx followup

Ordered this after a SAMe prescription given by the vet ran out. Mixes easily in wet food with a little added water. Dog eats it without hesitation.

Rated 5 out of 5 stars
By lisa on May 14, 2021

More Like a puppy

I wasn't sure if my baby would even touch this, since she is so finicky about her food - But it was great. Being a powder it was easy to mix in food and easy for her to eat. Highly recommend this powder especially for small dogs.

Rated 4 out of 5 stars
By Vicky on Jan 27, 2021

SAMe Premium

I have been giving this to my senior dog to, hopefully, help with her Cognitive issues. Since I have been giving it to her in her evening meals, she seems to be less confused as she has been. She has Degenerative Myelopathy so I am trying to do everything I can to prolong her life. She is also on Carprofen which is hard on her liver.

Rated 5 out of 5 stars
By Melis on Dec 3, 2020

works wonders, easy to consume

Product was recommended to us by our vet for our senior dog with high liver enzymes. The powder is great as easy to mix into feed for my picky eater. Liver has improved since taking and he has a much better appetite.