Comfortis Chewable Tablet for Dogs, 10.1-20 lbs, & Cats, 6.1-12 lbs, (Orange Box)

By Comfortis
Rated 4.1585 out of 5 stars
Prescription Item

Pet Weight:

Selected: Pet Weight:

Pet Weight:

Selected: Pet Weight:

Why Autoship?

  • Save 5% on all future Autoship orders
  • Set your schedule based on your pet's needs
  • No fees, no commitments - skip, change or cancel anytime.
In Stock
FREE delivery
Usually arrives in 3-5 days
We'll collect your pet's prescription information at Checkout.

This item requires prescription approval.

Medications ship separately. Delivery times may vary.

About This Item


Comfortis is a chewable medication prescribed by veterinarians for dogs and cats to help treat — and possibly even prevent — flea infestations for up to one month. These flavored tablets can be added to your pet's favorite food and only need to be given to your canine companion once a month to help combat fleas.

Proudly sourced directly from the manufacturer or their approved distributor. Guaranteed genuine and backed by the manufacturer.

See More




Play Video: Learn More About Comfortis From Our Team of Experts
Learn More About Comfortis From Our Team of Experts

Frequently Bought Together

ReviewsWrite a Review

Rated 4.1585 out of 5 stars
164 Ratings
Would recommend to a friend

163 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 5 out of 5 stars
By Cindy on Oct 7, 2023

Love Chewy!

I ordered Comfortis flea medication, with a script from her Veterinarian. She has thrown up other flea control medications in the past, when the veterinarian office was out of Comfortis,so this product has worked for her for years. Now, I can only order it through and so very happy I can. It was delivered quickly! Me and my fur baby thank everyone at

Rated 3 out of 5 stars
By Sharon on Nov 27, 2023

Taste issue

Crushed tablet, mixed thoroughly into generous amount of hungry cat's favorite food. She wouldn't eat it. Medication must have an unsavory odor or taste. Don't recommend if your pet is a picky eater.

Rated 1 out of 5 stars
By SmartMule on Sep 19, 2023

Chewable? NOT!

I have to have an oral solution for one of my cats. I used to give her Program -- ground it with a pill grinder, put in food, gone. THIS STUFF SMELLS MEDICINAL THE MINUTE YOU OPEN THE PACKAGE -- not even medicinal, like some off, artificial odor. Still, didn't try to mix all in at one time, just about a fifth of the tablet. Cat won't touch it. I finally got her to eat some of it by putting yeast flakes on top of the foo. I will never buy this product again -- false advertising to list this as chewable for cats -- heck, it's not even edible!!

Rated 3 out of 5 stars
By Suzie on Oct 5, 2023

Pills are a bit big for cat to swallow comfortably. They would not eat chewable.

I think they made my cats nausea out. All 4 would not eat for almost 2 days. I’m happy I fed them right before dosing them. Pills are not chewable. Too big to push down throat. I’m so glad I put butter on them first. I thought they would be easier on them than the topical. The cost should at least make them so a cat will eat them!

Rated 4 out of 5 stars
By Anita on Nov 3, 2023


only good for 2 of my 4 cats. The one wou;dn't touch it and it made the other one sick The other 2 don't seem to have any problem with it. Would reccommend it cautiously

Rated 1 out of 5 stars
By Rachael on Aug 8, 2023

Be careful

Bought a 6 month supply. I gave my sweet baby just one of the pills (half one day in a gel cap and half the next day same way) but he had the worst reaction ever. Vomiting, pain, rapid breathing and dehydration. Please talk to your vet and make sure your baby can handle these pills. I hear they work great but my Lil Bit was extremely sick it, requiring multiple emergency vet visits and treatments to get him to being able to eat, drink and breathe normally again. After a week, he is starting to eat on his own (he's been syringe fed for days) he is getting better, but we dont know the extent of the damage yet. I will never use these again.

Rated 5 out of 5 stars
By Comfortis on Jul 17, 2023

This works! However…

I gave this to my cat after the topical meds were causing her to have an allergic reaction. I say however, because the first time she took it she vomited and salivated uncontrollably. This is said to be one of the side effects. I have medication I take for my upset stomach called Zofran so I called my vet to see if I could give that to her when I administer the medication. He said it was safe so next time I tried it and voila! No more upset tummy! She was on this for 2 years until COVID made it unavailable and I had to start using Credelio (also great)!

Rated 5 out of 5 stars
By Cindy on Aug 1, 2023


I love this product for my cats. It's the only thing that works to get rid of their fleas. Topical flea treatment just doesn't work for us. I am so glad Chewy is carrying this again because my cats were miserable when we couldn't get it. I do have to crush it and hide it in a really fishy smelling wet food to get them to eat it but that's ok. Chewy please keep making this available for purchase.

Rated 4 out of 5 stars
By IwantOneMonthOnlynotSix on Aug 27, 2023

They haven't had this product in MONTHS. Now its finally back and they want you to buy a 6 MONTH SUPPLY, WHY?? Why cant i just buy 1 month. I don't need all that. It works better than any of the other flea pills I've used but thats ridiculous

Rated 2 out of 5 stars
By cass23 on Apr 28, 2023

not for picky eaters

Spent the $100 as my vet said this would be a great alternative to topical since my cat is allergic to topical and is suffering from previous flea bites (that she is also allergic to). After reading reviews I our hard a pill crusher and mixed the equivalent of half a pill in powder form in with my cats canned food just to see if she would tolerate it as I was weary of it upsetting her stomach. She ate the food until she must have picked up on the taste of the powder. Immediately stopped eating and won’t touch her bowl. I tried giving her the rest of the powder by hand feeding her gravy and she won’t go near it at all. I’m hoping the little bit she MIGHT have consumed helps her itching? But I’m not sure she ate any of pill powder at all so this might have been a waste.