Coraxis (moxidectin) Topical Solution for Dogs, 55.1-88 lbs, 6 treatment (Blue Box)

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Dogs are part of the family, which is why it’s important to help keep them safe from parasites that can pose potentially dangerous health risks. Coraxis Topical Solution for Dogs is an easily absorbed topical medication that helps kill incoming heartworm larvae nonstop for 30 days. This treatment is also formulated to help treat and control intestinal parasites like roundworms, hookworms and whipworms. Every Coraxis prescription solution comes as one easy monthly application. This medication is designed for dogs weighing between 55.1 and 88 pounds.


Coraxis is indicated for the prevention of heartworm disease caused by Dirofilaria immitis.

Possible Side Effects

Contact your veterinarian if your dog experiences localized pruritus, hematochezia, diarrhea, vomiting, lethargy, inappetence or pyoderma.

Drug & Food Interactions

In a well-controlled field study the same dose of topical Moxidectin was used safely in dogs concomitantly receiving ACE inhibitors, anticonvulsants, antihistamines, antimicrobials, chondropprotectants, corticosteroids, immunotherapeutics, MAO inhibitors, NSAIDs, ophthalmic medications, sympathomimetics, synthetic estrogens, thyroid hormones, and urinary acidifiers.


Do not administer this product orally.

Dosage Chart

Color on BoxWeight RangeVolumeStrengthDosageProduct Page
Green3-9 lbs0.4 mL10 mg MoxidectinApply once a month by topical administration✓-Click Here
Teal9.1-20 lbs1.0 mL25 mg MoxidectinApply once a month by topical administration✓-Click Here
Red20.1-55 lbs2.5 mL62.5 mg MoxidectinApply once a month by topical administration✓-Click Here
Blue55.1-88 lbs4.0 mL100 mg MoxidectinApply once a month by topical administration✓-Click Here
Brown88.1-110 lbs5.0 mL125 mg MoxidectinApply once a month by topical administration✓-Click Here
  1. Prescribing Information

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  • Item Number
  • For Use With
  • Common Brand Name(s)
  • Generic Name
  • Brand
  • Breed Size
    Large Breeds
  • Product Form
  • Strength
    100 mg Moxidectin
  • Health Condition
    Whipworms, Heartworms, Hookworms, Roundworms
  • Drug Type

Active ingredients: 100 mg Moxidectin.

Recommended Dosage

Apply topically once per month.

Storage Instructions

Store at temperatures from 39°F - 77°F avoiding excess heat or cold.


How does Coraxis for Dogs work?

Coraxi is a transdermal formulation that is applied to the skin, where it is quickly absorbed and distributed throughout the body. From there, it accumulates in fatty tissue, which acts as a drug reservoir, releasing moxidectin into the bloodstream for 30 days.

Why should I recommend a transdermal formulation?

The transdermal formulation of Coraxis allows it to achieve and maintain high plasma levels, continuously killing susceptible stages of heartworms for 30 days. Administered monthly, Coraxis also provides treatment and control of hookworms, roundworms and whipworms.

How often can Coraxis be used?

As heartworms and intestinal parasites are all-too-common threats to the health of dogs in your care, we recommend the monthly use of Coraxis for Dogs year round.

Is Coraxis available for dogs of all sizes?

Coraxis is approved for dogs and puppies 7 weeks of age and older that weigh at least 3 pounds. It has been formulated for a wide range of weights and can be purchased through your Bayer sales representative.

Available in single-unit cartons of six tubes (monthly doses) in five different sizes.

Weight Range (lbs)Strength
3-9 lbs6 x 0.4 mL tubes
9.1-20 lbs6 x 1.0 mL tubes
20.1-55 lbs6 x 2.5 mL tubes
55.1-88 lbs6 x 4.0 mL tubes
88.1-110 lbs6 x 5.0 mL tube
Rating: 3.6 of 5 stars 3 Reviews 3 Reviews 3.7 out of 5 Stars

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Rating: 3.6 of 5 stars 3.7 / 5

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  • 5 out of 5 stars

    Coraxis HW Prevention

    By on

    I have been using Coraxis for several months on my six dogs. Moxidectin is the one of the most effective HW preventions on the market. I like that it is topical so I don’t have to make sure my dogs swallowed their oral meds and didn’t through them up later.

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  • 1 out of 5 stars

    My poor dog has had diarrhea every day following application

    By on

    Since the day following application, my dog has had diarrhea - she isn't going more frequently, but every stool is loose when she goes. She has had only her normal dog food (no treats whatsoever) so I'm certain it is the topical. Won't be using the other 5 for certain.

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  • 5 out of 5 stars

    Heartworm treatment for my dog Bullet

    By on

    The site was very user friendly and ordering was simple. I received the medicine faster than expected. Overall good experience.

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