Diphenhydramine HCl (Generic) Capsules

Prescription Item

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Strength: 25-mg
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Count: 1 capsule
  • 1 capsule In stock

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Diphenhydramine HCI, commonly known as Benadryl is an antihistamine prescribed to help relieve allergy symptoms. Some of these symptoms may include coughing and itching caused by insect bites, pollen, house dust along with other allergy triggers. This medication may also help control vomiting and motion sickness and may be prescribed as a mild sedative to help treat muscle tremors caused by toxins or other medications. Customers may receive this drug under the names Benadryl (Warner Lambert), Histacalm (Virbac).


Temporarily relieves symptoms due to upper respiratory allergies, such as itching skin, sneezing and itchy, watery eyes.

Possible Side Effects

Side effects of diphenhydramine include drowsiness, dry mouth and urinary retention. Vomiting and diarrhea have also been reported in rare cases.

Drug & Food Interactions

Always tell your vet about other medications the pet is taking. The capsule should not be mixed or dissolved in food.


Do not use this medication in those allergic to it or other antihistamines. Do not use in those with glaucoma, prostate disease, urinary obstruction and high blood pressure. Do not use in pregnant or nursing animals. Use with caution when given with other CNS (central nervous system)-depressant drugs, such as tranquilizers or barbiturates. Always tell your vet what other medications the pet is taking.

NOTE: For Generic Medications, picture displayed may not depict actual product. Generic medications may vary from one order to the next by size, color and shape depending on manufacturer. Customers may receive the same drug under the names Benadryl (Warner Lambert), Histacalm (Virbac).

This drug is FDA-approved for human use. However, it is common practice for veterinarians to prescribe such drugs for use in dogs and cats.

  1. Prescribing Information

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  • Item Number
  • Brand


  • Dosage Measure

    Use according to your veterinarian's instructions.

  • Common Brand Name(s)

    Benadryl (Warner Lambert), Histacalm (Virbac)

  • Generic Name

    Diphenhydramine Hydrochloride

  • For Use With

    Dogs & Cats

  • Product Form


  • Health Condition

    Motion Sickness, Anxiety, Allergies

  • Drug Type




Recommended Dosage

Use as directed by your veterinarian.

Storage Instructions

Store at temperatures between 68° - 77°F.


What is Diphenhydramine?

An antihistamine used to relieve allergy symptoms, insect stings, motion sickness, travel anxiety, and other conditions.

What are the benefits of Diphenhydramine?

Relieves coughing, allergy symptoms and itching caused by insect bites. Can also be used as a sedative to treat motion sickness and anxiety.

How is this medication given?

Use as directed by your veterinarian.

How does this medication work?

As an antihistamine, Diphenhydramine counteracts the effect of histamine, which causes symptoms like itching and sneezing.

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