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Advantage II Flea Treatment for Dogs 3-10 lbs

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Advantage II Flea Treatment for Dogs 10 lbs and Under is a convenient monthly topical flea treatment for dogs and puppies 7 weeks of age and older. Advantage II for dogs contains an (imidacloprid) and an insect growth regulator (pyriproxyfen) to kill all life stages of fleas. Furthermore, it kills fleas through contact, so they don’t have to bite your dog to die. One convenient application of Advantage II for dogs keeps working for 1 month.

Key Benefits

  • Kills all flea life stages including flea eggs, larvae, pupae, and adult fleas
  • Kills fleas within 12 hours of initial application
  • Once a month topical treatment for fleas and lice
  • Works through contact, so fleas don’t have to bite to die. Provides waterproof protection
  • For use only on dogs and puppies 7 weeks and older and weighing 3-10 lbs.


DO NOT USE ON CATS. Do not apply to puppies or dogs weighing less than 3 lbs. Do not get this product in your dog's eyes or allow your dog to ingest this product. ALWAYS read the entire product label prior to use.

Active Ingredients

  • 9.1% Imidacloprid
  • 0.46% Pyripoxyfen

See all items by Advantage II

  • Item Number
  • Brand
  • Breed Size
  • Lifestage
    Adult, Puppy


  • Use only on dogs. Do not use on other animals.
  • Remove one applicator tube from the package.
  • Hold applicator tube in an upright position. Pull cap off tube.
  • Turn the cap around and place other end of cap back on tube.
  • Twist cap to break seal, then remove cap from tube.
  • For Dogs 10 lbs and under & 11-20 lbs: The dog should be standing for easy application. Part the hair on the dog's back, between the shoulder blades, until the skin is visible. Place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin. Do not get this product in your dog's eyes or mouth.

  • For Dogs 21-55 lbs & Over 55 lbs: The dog should be standing for easy application. The entire contents of the Advantage II tube should be applied evenly to three or four spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of the solution at any one spot that could cause some of the solution to run off the side of the dog. Do not get this product in your pet's eyes or mouth.

  • Do not reuse empty container. Wrap container and put in trash.

  • In case of a severe flea infestation, retreatment may be necessary earlier than four weeks. Do not retreat more often than once every seven days. After flea control is attained, return to a monthly schedule.

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Customer Reviews

Advantage II Flea Treatment for Dogs 3-10 lbs is rated 4.6 out of 5 by 60.
Rated 5 out of 5 by from It works! My dear sweet toy poodle who has not seen one single chemical in his 10 years on this earth is still alive. I don't vax and he is raw fed. We have managed the fleas with natural topicals and DE topical and in his food but this year has been horrendous. He was MISERABLE. Calm Coat products would help a little but.... So I finally gave in and applied this yesterday and almost immediately he was able to relax and so far he has been so much better. He'll still scratch but only for a few minutes. It has truly been a miracle. I'd also like to thank the seller profusely for such quick shipping. And also a great price and reasonable shipping. You beat Amazon on this one :o) And sorry folks but we are praying for an early frost....just enough to kill the blasted fleas and still have a nice autumn.
Date published: 2016-09-24
Rated 5 out of 5 by from Most places don't offer smaller packs I love Advantage because it works. I have 2 small dogs and 2 big dogs so buying 4 or 6 packs is expensive. Chewy is one of the few places where you can buy smaller packs. Helps when you're on a monthly budget. Shipping was super quick too.
Date published: 2016-12-17
Rated 5 out of 5 by from Fleas dying Gave on a Wednesday, fleas dying by next day. Great product!
Date published: 2017-01-16
Rated 5 out of 5 by from Works amazing My puppy is very allergic to fleas, like pull his hair out allergic, and as soon as I put this on him it made such a difference.
Date published: 2016-12-03
Rated 5 out of 5 by from Miracle Product! The fleas at my home in Raleigh, NC were getting to be way to much to handle for my two mini weiner dogs! We'd treat them with flea spray and give them baths to no avail, it was that time of year where for every flea you pick off there are three more! My dogs were really unhappy and restless, always scratching so we decided it was time to bite the bullet and try a product. We used to use frontline for many years but my friend who works at Bansfield says they don't recommend it anymore because they haven't changed their formula in years so fleas are immune. Advantage 2 had pretty good reviews and was affordable so I decided to try it. My dogs weigh 8 and 11 pounds respectively so I used the small application (3-10) pounds on both rather than buy two different types. I washed my dogs and all of their bedding before applying it and the effects were almost instant! I used one application for each even though you can reapply if its really bad. Within a day I saw no fleas on my dogs and they slept better than they had in months! It's been a week and I only say one baby flea on my dog where before they would have 10 at a time. Great product, highly highly recommended! you should always watch your dogs when trying new products to seeE if they'll have a reaction, but I will say one of my dogs has been allergic to other products in the past but was fine with this product. no problems! :)
Date published: 2016-10-31
Rated 2 out of 5 by from Fleas persist a week later. A week after applying the entire tube of product to my 5 lb. dog, he was still battling fleas. Right now 1 1/2 weeks later, all is calm. He never had a bad infestation, just 1 or 2 at a time, but he's very allergic to fleas. My daughter tells me the product is NOT water proof as the packaging states. I bathe my dog weekly so I hope it continues to work or I send it back.
Date published: 2016-12-21
Rated 5 out of 5 by from Very happy with product and prompt delivery The product came as expected. I actually had to call immediately after I placed the order in order to confirm when I should expect it. The customer service representative was excellent and told me that it would probably come overnight delivery. My order came the very next day.
Date published: 2017-01-11
Rated 5 out of 5 by from Reliable! When it comes to flee meds, there is not time for guessing if a product works. Advantage II immediately works! Pets are happy again. Humans are not experiencing flee bites. House goes back to normal. This product is reliable and works.
Date published: 2017-02-07
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