On Sale

Bio Spot Active Care Flea & Tick Spot On for Dogs (31-60 lbs)

  • Was:


  • Price:

    $10.79 FREE 1-2 Day Shipping over $49

  • You Save:

    $11.13 (51%)

In stock
3 treatments
  • 1 treatment
  • 3 treatments
- Quantity +


Bio Spot Active Care Flea & Tick Spot On for Dogs ensures continuing long-term protection for your pet. Bio Spot Active Care topical gel kills adult fleas and ticks and contains an insect growth regulator to kill flea eggs and larvae for up to 30 days. Included applicator helps keep the liquid off your hands, makes it easier to part your dog's fur, gets liquid down to your dog's skin and is easy to load and apply.

Key Benefits

  • Includes Bio Spot Smart Shield Applicator which helps keep the liquid off your hands, makes it easier to part your dog's fur, and gets liquid down to your dog's skin
  • For use on dogs and puppies 12 weeks of age or older
  • Kills fleas, flea eggs, flea larvae and deer ticks for up to 1 month. Also kills mosquitoes that may transmit heartworm disease or West Nile virus
  • Fast-drying formula contains a coat conditioner for a non-sticky application, and works with the biology of your dog by spreading through the oils of their skin
  • Formulated with an Insect Growth Regulator (IGR) to break the flea-life cycle


DO NOT USE ON CATS. Keep cats away from treats dogs/puppies for 24 hours. If applied to a cat or ingested by a cat, contact your veterinarian. Do not allow children to apply this product. Do not use more than one tube per dog/puppy and do not treat more than once per month. Do not allow your dog/puppy to ingest this product. Do not bathe your dog 48 hours prior to application.

Active Ingredients

  • Etofenprox 50.00%
  • Piperonyl Butoxide 9.10%
  • N-octyl bicycloheptene dicarboximide 0.91%
  • Pyriproxyfen 0.45%
  • (S)-Methoprene 0.23%

For Bio Spot Defense Refill, Click here.

See all items by Bio Spot

  • Item Number
  • Breed Size
    Medium, Large
  • Lifestage
    Puppy, Adult


  • OPEN: Use finger scoop to lift open green door.
  • LOAD: To load, place tube white side up into the open Smart Shield applicator with front of tube placed under tab on door. Ensure that tube fits securely in the Smart Shield applicator.
  • CLOSE: Gently close the green door and the tube will snap open.
  • APPLY: The dog/puppy should be standing for easy application. To apply, use tip to part hair and get next to dog’s/puppy’s skin. Press circle on green door once at each of four or five evenly placed spots, for large or extra-large dogs (or at each of two to three evenly placed spots for medium or small dogs) between the shoulder and the base of the tail. Do not apply an excessive amount of the solution at any one spot that could cause some of the solution to run off the side of the dog/puppy. Do not spread this product by hand over the dog/puppy. Although the dog’s/puppy’s skin and hair oils will distribute the application over the entire dog/puppy, brushing the dog/puppy 12-24 hours after treatment will help to distribute the material over the skin.
  • DISPOSE: When finished, hold the Smart Shield® applicator over trash. To dispose of empty tube, open green door and drop empty tube into trash or offer for recycling if available. Close applicator device door and store in original package.
  • RETREAT: Do not reapply product for 30 days. Do not treat more than once per month.

Pet Lovers Also Bought

Customer Reviews

Bio Spot Active Care Flea & Tick Spot On for Dogs (31-60 lbs) is rated 3.5 out of 5 by 46.
Rated 1 out of 5 by from Doesn't work! I put this on both of my dogs. It has not had any affect on the fleas at all! I would not recommend this product to anyone. My poor dogs are itching like crazy. Going to find something better. I have a lab, which I shaved because I know it is hard for flea medicine to get to her skin through her thick fur. I also have a dingo mix who has short fur. Both are still covered with fleas. Will resort to bathing and finding another more effective product.
Date published: 2017-03-06
Rated 5 out of 5 by from So Far So Good So Far So Good. My bully has only had one flea after application and that was because he sun bathes and I'm sure that lonely one just hoped on for a ride. He seems to not be infested with critters and that's always deserves a '5 star' rating from this mama!
Date published: 2017-03-20
Rated 5 out of 5 by from Works Great! I have used Bio Spot on all my Shelties for many years without any fleas or ticks ever.
Date published: 2017-03-09
Rated 1 out of 5 by from Unfortunately it doesn't work I was excited to find a healthier flea treatment, but it just doesn't work. The first round we tried, my English cocker spaniel had long fur, so after a shave and two flea baths and combing by a local groomer, I tried again. We even washed all the blankets (his and ours) and treated the rug and sofa. Then we tried the Biospot again, and it still didn't work. Don't bother with this product. I recommend that Chewy stop carrying it altogether.
Date published: 2016-11-18
Rated 1 out of 5 by from Did not get rid of one flea. My poor dog and cat. Before first application, I bathed my pets and let them fully dry. Then I applied the first one. I had to keep putting a homemade spray on them. One week later I saw that my dog had many more fleas. I bathed her and the cat and repeated my first steps. Still the fleas were present. I had to spend over $100 on Advantix and I continue to spray them with a homemade solution before they go out in the yard. I expected to see less fleas on them not more.
Date published: 2016-08-24
Rated 5 out of 5 by from good stuff! This is the best treatment I have found on the market! It kicks the other high priced stuff in the butt! I used it on Bella for a year, the local store stopped carrying it so I went to Chewy. I ordered it and 2 days later I received my order. Bella has sensitive skin and seems allergic to about everything, not this stuff! I've not found 1 flea on her! Thanks Chewy for great prices, selection and service! I signed up for auto refill.
Date published: 2016-09-03
Rated 1 out of 5 by from does not work Our dog stays indoors at least 95 percent the time, and has a horrible flea infestation after switching to this product. He has never had fleas or ticks using a popular (and expensive) competitor and now the entire house needs de-flead because he has spread them throughout. What a pain!
Date published: 2016-09-29
Rated 2 out of 5 by from messy I chose this over another product which was more expensive. My dogs are scratching so thinking the product didn't work for the full month like its suppose to. Its only been 2 weeks since I applied it. The treatment is more messy seeing u have to go from shoulder blade to tail. How much product is really reaching the skin rather than the hair. I can't shave each dog. It didn't give the dogs any bad reaction so thats one good thing. Have enough for another treatment so will see if it works any better and if not will think about going back to my other product.
Date published: 2013-08-26
  • y_2017, m_3, d_23, h_13
  • bvseo_bulk, prod_bvrr, vn_bulk_1.0.0
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_46
  • loc_en_US, sid_65159, prod, sort_[SortEntry(order=RELEVANCE, direction=DESCENDING)]
  • clientName_mrchewy