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Frontline Plus Flea & Tick Treatment for Extra-Large Dogs (89-132 pounds)

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In stock
  • 3 treatments
  • 6 treatments
- Quantity +


  • Item Number
  • Breed Size
    Large, Giant
  • Lifestage
    Puppy, Adult

Frontline Plus doesn’t just kill adult fleas and ticks but also slays the next generation of flea eggs and larvae. Plus, it works non-stop for 30 days on dogs. Frontline Plus has 2 tough killing ingredients. The 1st, fipronil, kills adult fleas and ticks. The 2nd, (S)-methoprene, attacks flea eggs and larvae. They work together to kill all month long. Plus, it breaks the flea life cycle. By also destroying the next generation of flea eggs and larvae, Frontline Plus gives you the power to help prevent a flea infestation on your pet. Frontline products are highly recommended by veterinarians for flea and tick control for dogs.

Key Benefits

  • Provides fast-acting, long-lasting treatment and control and is safe for use on dogs and puppies 8 weeks or older between 89-132 pounds
  • Kills adult fleas, ticks, chewing lice, mites, and flea eggs and larvae that may transmit Lyme disease
  • Highly recommended by veterinarians for flea and tick control for dogs
  • Contains fipronil to kill existing flea and tick infestations. It also kills fleas before they lay eggs, effectively preventing reinfestation for 30 days
  • Provides waterproof effectiveness so that it won't wash off from swimming or baths

See all items by Frontline

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Customer Reviews

Rated 4.8 out of 5 by 89 reviewers.
Rated 1 out of 5 by Fleas are winning! For years this product has been effective and safe. The past few months I have noticed a serious decline in effectiveness. I would alternate between products to no avail. Unsure of the reason, but several friends have the same issues. October 19, 2016
Rated 5 out of 5 by Great product I like Frontline Plus as it does not cause any irritation on the site of application as other products do, and it does the job with all my dogs. October 21, 2016
Rated 2 out of 5 by Nothing good This product said it would kill fast and I'm waiting another two weeks before I can put it it on again,never will I buy it again October 14, 2016
Rated 5 out of 5 by no more fleas before frontline my dog had a lot of fleas on this skin. after just one application and a bath, there were no more fleas. Great product and will order more in a couple of months October 6, 2016
Rated 5 out of 5 by This product has worked well for both fleas and ticks! I have used this easy to apply product on 5 different dogs, small, medium and large, over the last 15 years. Ticks and fleas don't stand a chance of staying alive! September 22, 2016
Rated 5 out of 5 by Great Product! Fast delivery Love the Frontline Plus! I have used it for years and never see a flea or tick on my two labs! This year we had a friend bring their dog for a visit and it had tons of fleas so we just used it a little quicker than usual and problem solved!! September 13, 2016
Rated 5 out of 5 by Worked for us. We rarely get any fleas where we live but we did this year and this took care of it. September 16, 2016
Rated 5 out of 5 by Works Great!!! This product is fantastic, and the shipping is so fast, I love Chewy.com best place for your pets needs!!!! September 7, 2016
  • 2016-10-23 T05:38:18.312-05:00
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