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Frontline Plus Flea & Tick Treatment for Large Dogs (45-88 pounds)

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6 treatments
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  • 6 treatments
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Description

Frontline Plus doesn’t just kill adult fleas and ticks but also slays the next generation of flea eggs and larvae. Plus, it works non-stop for 30 days on dogs. Frontline Plus has 2 tough killing ingredients. The 1st, fipronil, kills adult fleas and ticks. The 2nd, (S)-methoprene, attacks flea eggs and larvae. They work together to kill all month long. Plus, it breaks the flea life cycle. By also destroying the next generation of flea eggs and larvae, Frontline Plus gives you the power to help prevent a flea infestation on your pet. Frontline products are highly recommended by veterinarians for flea and tick control for dogs.

Key Benefits

  • Provides fast-acting, long-lasting treatment and control and is safe for use on dogs and puppies 8 weeks or older between 45-88 pounds
  • Kills adult fleas, ticks, chewing lice, mites, and flea eggs and larvae that may transmit Lyme disease
  • Highly recommended by veterinarians for flea and tick control for dogs
  • Contains fipronil to kill existing flea and tick infestations. It also kills fleas before they lay eggs, effectively preventing reinfestation for 30 days
  • Provides waterproof effectiveness so that it won't wash off from swimming or baths

Cautions

Your pet may experience some temporary irritation at the site of application. If signs persist or become severe within a few days of application, consult your veterinarian immediately. Observe your pet following treatment. Sensitivities may occur after using ANY pesticide product on pets. Please read entire manufacturer’s insert prior to using product. Approved for use in breeding, pregnant, or nursing animals. Consult with veterinarian before using on sick, medicated or aged animals.

Active Ingredients

  • Fipronil 9.8%
  • (S)-methoprene 8.8%

See all items by Frontline

  • Item Number
    49537
  • Breed Size
    Large
  • Lifestage
    Puppy, Adult

Instructions

  • Snap open the tip of the Frontline applicator away from your body and face.
  • Part your pet's hair between the shoulder blades until you can see the skin, and place the tip of the applicator on the skin.
  • Squeeze applicator to apply entire contents in a single spot on the skin monthly.
  • Allow 24 hours before bathing or swimming.

Additional Tips

  • Remove dog's collar
  • Apply as a spot between your dog's shoulder blades in 1 area that can't be licked.
  • Avoid touching the wet application spot.
  • Wait 24 hours to allow solution to dry before bathing or letting your dog swim.
  • Give each of your dogs its own complete dose.

Frequency of Application

  • When used monthly, FRONTLINE Plus completely breaks the flea life cycle and controls tick and chewing lice infestations. Do not reapply FRONTLINE Plus for 30 days.
  • FRONTLINE Plus kills adult fleas, flea eggs, and flea larvae for up to three months. FRONTLINE Plus also prevents development of all flea stages for up to three months. FRONTLINE Plus can control fleas for up to three months, however, if there is a high risk of reinfestation or if the pet has fleas which may cause flea allergy dermatitis, a once monthly application may be needed.
  • FRONTLINE Plus kills ticks for at least one month. A once monthly application is recommended where tick control is needed. FRONTLINE Plus kills all life stages of ticks (larva, nymph and adult).
  • FRONTLINE Plus kills ticks that may transmit Lyme disease, Rocky Mountain spotted fever, ehrlichiosis, babesiosis, anaplasmosis and other tick-borne diseases.
  • FRONTLINE Plus kills chewing lice for at least one month. A once monthly application is recommended where chewing lice control is needed.
  • FRONTLINE Plus aids in the control of sarcoptic mange infestations. Multiple monthly treatments are recommended for the elimination of mites.

Frequently Asked Questions

How does FRONTLINE Plus kill fleas and ticks?

FRONTLINE Plus has 2 secret weapons: fipronil and (S)-methoprene. Once FRONTLINE Plus is applied, this combo stores itself in the oil glands in your pet's skin. It then self-distributes continuously for 1 month to your pet's hair and skin through the hair follicles. Fleas or ticks that come in contact with your pet are dead meat.

How long does it take for FRONTLINE Plus to kill fleas?

In a study, FRONTLINE Plus began killing fleas 4 hours after application.1 Another study showed that within 12 hours, Frontline Plus killed 100% of fleas.2

Do fleas and ticks have to bite my pet for FRONTLINE Plus to work?

No. FRONTLINE Plus kills fleas and ticks through contact with your pet's haircoat. No biting necessary.

Why am I seeing more fleas on my pet after applying FRONTLINE Plus?

Fleas rise to the top of your pet's haircoat as they die. So if you start seeing more fleas after treating your pet, consider it a victory for the killing force.

After using FRONTLINE Plus, I still see fleas in my home. Why?

The fleas you see most likely started as flea eggs that were deposited in the environment before you began using FRONTLINE Plus. Consecutive monthly applications of FRONTLINE Plus will assist with the elimination of an indoor flea life cycle. In some geographical regions in the United States, it may be required to use the product year-round.

Does FRONTLINE Plus have an expiration date?

No. As long as you keep it at room temperature and sealed in its original packaging, FRONTLINE Plus will remain ready for battle.

How long after application can my pet be bathed or go swimming?

FRONTLINE Plus remains effective for 30 days, even if your pet swims or is bathed. After application, keep your pet from getting wet for 24 hours. If FRONTLINE Plus is to be applied after a bath, make sure your pet is completely dry before application.

Can I use it if my pet is on medication?

Before using FRONTLINE Plus, ask your vet about possible interactions with any medications your dog is taking.

Can I use FRONTLINE Plus if I have already applied another flea and tick control product?

Before using, consult your veterinarian.

Does FRONTLINE Plus kill anything else besides fleas and ticks?

You bet. FRONTLINE Plus also kills chewing lice.

Can FRONTLINE Plus be used on pets other than dogs and cats?

No. FRONTLINE Plus should be used on dogs and cats only. There are specific products based on what kind of pet you have and how much it weighs. Be sure to use the right product for your pet.

Can I apply it more than once a month?

Don't reapply FRONTLINE Plus before the month is through. It keeps working for a full 30 days.

How old does my pet need to be in order to have FRONTLINE Plus applied?

At 8 weeks your pet can start benefiting from the power of FRONTLINE Plus.

  1. Frontline Plus Use & Care Instructions

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Customer Reviews

Frontline Plus Flea & Tick Treatment for Large Dogs (45-88 pounds) is rated 4.7 out of 5 by 317.
Rated 4 out of 5 by from This product does what it says. Frontline really does kill the ticks and I have never had a problem with fleas. My only problem with it is the fact that it doesn't repel the ticks, so they still get brought inside. I have found many in his bed. Thankfully they were all dead. If they could add a repellent, it would be perfect, because I have tried others and they don't last.
Date published: 2017-02-04
Rated 5 out of 5 by from RECEIVED AS ORDERED WITH FAST DELIVERY ANOTHER EXCELLENT PRODUCT FROM CHEWY.COM I WILL BE ORDERING MORE FROM YOUR COMPANY IN THE FUTURE. THANK YOU.
Date published: 2017-01-11
Rated 5 out of 5 by from This product works. I have three German Shepherd dogs. The male was a therapy dog, but he is retired now. The middle dog is a therapy dog and is taken to three different facilities. The youngest dog is my Service Dog. She goes with me every where. This product is easy to apply, is odorless and works, especially since all dogs have to run and play in the backyard to help them remain good working dogs. Especially since I'm in the country and possums, squirrels and armadillos are present. And I know the squirrels have fleas, but my dogs don't.
Date published: 2016-12-14
Rated 5 out of 5 by from Upstate NY Can you say ticks we can.. living in upstate NY we have 2 things, one beautiful .., open wooded areas wooded parks and second, ticks, lots of ticks. I have been using Frontline for ten years there has not been one tick on my dog.
Date published: 2016-12-23
Rated 5 out of 5 by from Great savings! With my new member coupon I saved a considerable amount on a six-month supply of Frontline Plus for my Collie.
Date published: 2017-01-31
Rated 1 out of 5 by from Didn't work Our vet changed us to Revolution because this wasn't effective.
Date published: 2016-11-27
Rated 5 out of 5 by from Always works well but beware of imitations By purchasing from chewy I am always sure of getting the real deal at a fair price and quick shipping. This product has worked for us and our dogs for more than a decade with excellent results. It definitely kills ticks! We never ever have fleas either! I love chewy.com!
Date published: 2016-12-06
Rated 5 out of 5 by from Easy application We started using Frontline years ago when it was available only through the vet's office. Now that it is over the counter,it is much easier to purchase, and more affordable. Love Chewy.com. So efficient, so easy, and the prices are better than local pet stores.
Date published: 2016-12-14
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