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Frontline Plus Flea & Tick Treatment for Large Dogs (45-88 pounds)

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In stock
  • 3 treatments
  • 6 treatments
- Quantity +


  • Item Number
  • Breed Size
    Medium, Large
  • Lifestage
    Puppy, Adult

Frontline Plus doesn’t just kill adult fleas and ticks but also slays the next generation of flea eggs and larvae. Plus, it works non-stop for 30 days on dogs. Frontline Plus has 2 tough killing ingredients. The 1st, fipronil, kills adult fleas and ticks. The 2nd, (S)-methoprene, attacks flea eggs and larvae. They work together to kill all month long. Plus, it breaks the flea life cycle. By also destroying the next generation of flea eggs and larvae, Frontline Plus gives you the power to help prevent a flea infestation on your pet. Frontline products are highly recommended by veterinarians for flea and tick control for dogs.

Key Benefits

  • For dogs between 45 and 88 pounds
  • Stops flea infestation
  • Kills adult fleas, ticks, flea eggs and larvae
  • Prevents all flea stages (eggs, larvae, pupae) from developing
  • Kills ticks that may transmit diseases
  • Provides waterproof effectiveness
  • Offers a mighty killing force for a full 30 days

See all items by Frontline

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Customer Reviews

Rated 4.7 out of 5 by 294 reviewers.
Rated 4 out of 5 by Glad Frontline Plus is available without an Rx Used Frontline Plus for years and never had a problem. One vet was out of stock and did not know when he would get more. My other vet no longer carries the product and sold me a one month sample of ACTIVYL to try. I will never use it again. It's flea/tick activity may be the best but it is totally cosmetically inelegant. My dog had a grease strip down her back for two weeks until I finally got her groomed. Your pricing is competitive (Vet used to give me 2 free with six) September 18, 2016
Rated 5 out of 5 by Great protection We've been using Frontline on our German Shepherds for years now. Have never seen a tick of flea. Pricey but very effective. If skin irritation occurs (has for us), apply in small doses down the entire spinal column, not just between shoulder blades. September 18, 2016
Rated 5 out of 5 by long time user Have used Frontline Plus on our beagle since she was a pup. She is 9 yrs old now and have never had a problem. We also used it on our last dog (a mutt) and never had a problem. We started using it on our last dog when she had a terrible time with fleas one year. We never had a problem or had fleas in the house again. I highly recommend it! I also want to commend Chewy on their fast delivery. It is literally 2 days tops and it is on your doorstop. September 12, 2016
Rated 5 out of 5 by We always us this product. We have always used this on our dogs and cats. We do not like to keep any type of collars on them. We use their regular collars just for appointments and walks. September 18, 2016
Rated 5 out of 5 by Great product I've used this for years, very effective, never found a flea or tick on my babies. September 18, 2016
Rated 3 out of 5 by Works Frontline is a Great flea fighter. I've been using this for years. No side affects. I have 4 Dogs & 3 Cats use Frontline every month on All of them. September 15, 2016
Rated 5 out of 5 by Great to prevent fleas Great price, actually the best around. My dog never has fleas, because I use my frontline monthly. Your dog will thank you!!! September 15, 2016
Rated 5 out of 5 by Great Price The price was great and the product was received in a timely fashion. I would order again from Chewy. September 10, 2016
  • 2016-09-23 T06:00:26.376-05:00
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