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Frontline Plus Flea & Tick Treatment for Large Dogs (45-88 pounds)

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    $71.98 FREE 1-2 Day Shipping

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In stock
  • 3 treatments
  • 6 treatments


  • Item Number
  • Breed Size
    Medium, Large
  • Lifestage
    Puppy, Adult

Frontline Plus doesn’t just kill adult fleas and ticks but also slays the next generation of flea eggs and larvae. Plus, it works non-stop for 30 days on dogs. Frontline Plus has 2 tough killing ingredients. The 1st, fipronil, kills adult fleas and ticks. The 2nd, (S)-methoprene, attacks flea eggs and larvae. They work together to kill all month long. Plus, it breaks the flea life cycle. By also destroying the next generation of flea eggs and larvae, Frontline Plus gives you the power to help prevent a flea infestation on your pet. Frontline products are highly recommended by veterinarians for flea and tick control for dogs.

Key Benefits

  • For dogs between 45 and 88 pounds
  • Stops flea infestation
  • Kills adult fleas, ticks, flea eggs and larvae
  • Prevents all flea stages (eggs, larvae, pupae) from developing
  • Kills ticks that may transmit diseases
  • Provides waterproof effectiveness
  • Offers a mighty killing force for a full 30 days

See all items by Frontline

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Customer Reviews

Rated 4.7 out of 5 by 276 reviewers.
Rated 4 out of 5 by Always come back to this product Have tried other products before, even the "natural" ones, but none have worked as good as Frontline Plus. Don't seem to notice any side effects what so ever even on a dog that has multiple health issues including skin allergies. July 23, 2016
Rated 5 out of 5 by Does the job! Use once a month and you will never ever have fleas on your dog or in your home! July 21, 2016
Rated 5 out of 5 by Execellent Product We have been using this for years and have never been disappointed. July 19, 2016
Rated 5 out of 5 by Good product, good deal Good product, easy to apply. Seems to protect well. Chewy has the best price. July 19, 2016
Rated 5 out of 5 by Great product! Easy to apply and is not sticky on skin or hair. I have never seen a flea on my dog when using this. Highly recommend! Great product, great price and super fast delivery! Stay away from the cheap alternatives - they don't work as well and they are sticky and/or oily on the dog's skin/hair. July 11, 2016
Rated 5 out of 5 by What I wanted WHEN I wanted it. The item was as advertised and arrived almost before I ordered it. Certainly will look here for my next purchase. July 12, 2016
Rated 5 out of 5 by service is always prompt, cutious and extremely professional I recommend Chewy.com to all my friends and family. The service and products are unmatched. July 13, 2016
Rated 5 out of 5 by Works well! The actual product seems to work very well for us. I have never seen a tick or flea on any of my dogs once I have applied Frontline. Don't like having to use a toxic chemical on them, but I'm also just recovering from Lyme Disease from a tick I know for a fact one of my kitties brought me (BEFORE I used Frontline). So, for a few months out of the year all 7 of my cats and dogs have to have this stuff absorbed into their skin. :( July 4, 2016
  • 2016-07-28 T10:36:25.599-05:00
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