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K9 Advantix II Flea & Tick Treatment for Dogs 21-55 lbs

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K9 Advantix II Flea Treatment for Dogs 21-55 lbs offers broad spectrum flea control and protection against ticks and mosquitoes, too. It is specifically formulated for dogs and comes in a convenient, monthly topical application that not only kills but also repels fleas, ticks and mosquitoes. K9 Advantix II also kills all life stages of fleas, repels biting flies and kills lice. It contains imidacloprid, permethrin and pyriproxyfen that work in concert to repel and kill parasites that can potentially transmit disease-causing organisms. K9 Advantix II is a flea treatment for use on dogs 7 weeks and older.

Key Benefits

  • Specifically formulated for dogs and comes in a convenient, monthly topical application that not only kills but also repels fleas, ticks and mosquitoes
  • Repels and kills ticks of all types including deer ticks, American dog ticks, Brown dog ticks and Lone Star ticks
  • Prevents fleas on treated dogs from infesting your home
  • Kills fleas on dogs within 12 hours and continues to prevent infestations for a month
  • Contains imidacloprid, permethrin and pyriproxyfen which work to repel and kill parasites that can potentially transmit disease-causing organisms


DO NOT USE ON CATS. Do not get this product in your dog's eyes, or allow your dog to ingest this product. ALWAYS read the entire product label prior to use.

Active Ingredients

  • Imidacloprid, 8.80%
  • Permethrin*, 44.00%
  • Pyriproxyfen, 0.44%
    *cis/trans ratio: max 55% (±) cis and min 45% (±) trans

See all items by K9 Advantix II

  • Item Number
  • Brand
  • Breed Size
  • Lifestage
    Puppy, Adult


Topical prevention and treatment of ticks, fleas, mosquitoes, biting flies and lice for monthly use on only dogs and puppies 7 weeks of age and older. Monthly treatments are required for optimal control and prevention of fleas and ticks. The entire contents of the K9 Advantix II tube should be applied evenly to four to six spots on the top of the back from the shoulders to the base of the tail. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin.

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Customer Reviews

Rated 4.7 out of 5 by 325 reviewers.
Rated 5 out of 5 by Does the job I have been using K9 Advantix II for several years. I live in a wooded area and take my dog for walks in the woods every week, all 4 seasons. I rarely find a tick and when I do it is near death. in addition, it's easy to apply. January 16, 2017
Rated 5 out of 5 by The Best I have always used K9 Advantix for my dogs. I always purchased from my vet. My vet recently switched and is only offering Vectra and Frontline. I tried both and neither worked for my dog. We live in an area with a high Lyme Tick infestation and I was still finding ticks on my dog. I went online - compared pricing and ended up purchasing this and Advantage for my indoor cat. My (indoor) cat came from the SPCA and we could NOT seem to get rid of a couple fleas. I was concerned about the fleas getting out of control. This is the ONLY flea and tick product you should purchase! December 29, 2016
Rated 5 out of 5 by Better than other brands I have used I was amazed at the service from Chewy. The product was at my door the next day after ordering. January 10, 2017
Rated 5 out of 5 by Great tick medication Since I've used this on my puppy, she hasn't had anymore ticks! Great product! December 29, 2016
Rated 3 out of 5 by This just doesn't do a good job of controlling fleas & t ticks Doesn't work well. Twice as expensive as our previous product, but less than half as effective. December 24, 2016
Rated 5 out of 5 by Awesome flee and tick treatment This product works well on Fleas, Ticks and Mosquitoes. December 25, 2016
Rated 5 out of 5 by No fleas no ticks So far so good, no fleas no ticks. Since I've used this product there hasn't been any fleas or ticks on my dog. I am happy with this product and would recommend to others. I actually don't treat every month but every three months because I just think its over kill to do it every month but still seems to be working well. December 17, 2016
Rated 5 out of 5 by Awesome Product Awesome deal. Cheap price, I got 4 for the price of 3 from my Vet and saved $12. December 18, 2016
  • 2017-01-18 T06:52:38.882-06:00
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