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K9 Advantix II Flea & Tick Treatment for Dogs 21-55 lbs

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K9 Advantix II Flea Treatment for Dogs 21-55 lbs offers broad spectrum flea control and protection against ticks and mosquitoes, too. It is specifically formulated for dogs and comes in a convenient, monthly topical application that not only kills but also repels fleas, ticks and mosquitoes. K9 Advantix II also kills all life stages of fleas, repels biting flies and kills lice. It contains imidacloprid, permethrin and pyriproxyfen that work in concert to repel and kill parasites that can potentially transmit disease-causing organisms. K9 Advantix II is a flea treatment for use on dogs 7 weeks and older.

Key Benefits

  • Specifically formulated for dogs and comes in a convenient, monthly topical application that not only kills but also repels fleas, ticks and mosquitoes
  • Repels and kills ticks of all types including deer ticks, American dog ticks, Brown dog ticks and Lone Star ticks
  • Prevents fleas on treated dogs from infesting your home
  • Kills fleas on dogs within 12 hours and continues to prevent infestations for a month
  • Contains imidacloprid, permethrin and pyriproxyfen which work to repel and kill parasites that can potentially transmit disease-causing organisms


DO NOT USE ON CATS. Do not get this product in your dog's eyes, or allow your dog to ingest this product. ALWAYS read the entire product label prior to use.

Active Ingredients

  • Imidacloprid, 8.80%
  • Permethrin*, 44.00%
  • Pyriproxyfen, 0.44%
    *cis/trans ratio: max 55% (±) cis and min 45% (±) trans

See all items by K9 Advantix II

  • Item Number
  • Brand
  • Breed Size
  • Lifestage
    Puppy, Adult


Topical prevention and treatment of ticks, fleas, mosquitoes, biting flies and lice for monthly use on only dogs and puppies 7 weeks of age and older. Monthly treatments are required for optimal control and prevention of fleas and ticks. The entire contents of the K9 Advantix II tube should be applied evenly to four to six spots on the top of the back from the shoulders to the base of the tail. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin.

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Customer Reviews

Rated 4.7 out of 5 by 307 reviewers.
Rated 5 out of 5 by This product won't bug your dogs! I have used this product for several years and never found a tick or a flea on any of my dogs. They also were ever scratching from mosquito bites. I tried going without it this summer and ended up with dogs that were constantly being attacked by mosquitos. We also had the upsetting discovery that fleas and dear ticks really do live in non-wooded busy suburbs. Once starting it again, the bugs stayed away from my dogs. I will never go a non-frozen season without this product again! October 27, 2016
Rated 5 out of 5 by So easy! The price was so good for this six month supply. It was my first time applying a flea and tick treatment and it could not have been easier. We'll see if it is as effective as claimed but I feel secure because other customer reviews gave it high marks. October 23, 2016
Rated 4 out of 5 by Working so far I switched to K9 Advantix II after Frontline stopped working. Seems to be keeping the fleas and ticks off my dogs so far. October 28, 2016
Rated 3 out of 5 by Not sure about this I have used K9 Advantix for a couple years now and it's worked great. My dog has went all summer without a single scratch up until September. Since then I have found a flea on her a couple times and she has went into full blown flea allergy dermatitis and has been on allergy/steroid med for weeks now. I have never missed a dose of Advantix on her and don't understand why this is happening. I loved this product but it doesn't seem to work anymore. October 19, 2016
Rated 5 out of 5 by Have used this product for many years We have a very strong flea population here and after having problems with Frontline I've been told by our friend and Vet to use this product. Since changing I've never had a flea issue and this has been over 10 years now. I would not go back to any other product. Ticks die off fast as well as it repels mosquitoes. October 22, 2016
Rated 5 out of 5 by Exactly as it states, Shipped in US, Shipped fast and free :) It's wonderful to get the exact product from the US (although many are made overseas). I've had a couple of other dealers and I'd get a shipment from Hong Kong or New Zealand and it didn't work as well as what I had bought from my vet. This one does at half the price. My vet charges about $30 a month for one of these, I got 6 months work for considerably less and it's working great on our Cairn terrier mix. No ticks and no itches for her or us. I will be back and highly recommend you check here first. October 17, 2016
Rated 5 out of 5 by No flea or ticks with this medication I am not one to bad mouth a product, that being said, at one time I used Frontline for my dog, think the ticks became immune to frontline so I changed due to the recommendation of fellow dog owners and now use Advantix without and issues its a great product IMHO. I hope you have the same results. October 21, 2016
Rated 5 out of 5 by Works good I use it on all three dogs. Find dead ticks on the floor so I know it works. No bad reactions on the dogs. October 25, 2016
  • 2016-10-31 T06:32:31.842-05:00
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