Nutramax Dasuquin with MSM Joint Health Chewable Tablets Large Dog Supplement

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Nutramax has combined over ten years of clinical use and research on their joint health supplement Cosequin with their research in advanced joint health ingredients in developing Dasuquin, a cost-effective formulation for dogs. Dasuquin combines NMX1000 ASU (avocado/soybean unsaponifiables) and decaffeinated tea with Cosequin's FCHG49 glucosamine hydrochloride and TRH122 low molecular weight chondroitin sulfate to provide the most comprehensive joint health management formula available for dogs. Dasuquin is a dual synergistic formula: its specific glucosamine hydrochloride and low molecular weight chondroitin sulfate have demonstrated synergy in stimulating cartilage matrix production, while ASU also acts synergistically with glucosamine.

Key Benefits

  • \#1 veterinarian recommended brand
  • Chewable tablets for Large dogs (over 60 pounds)
  • Most comprehensive joint health management formula available for dogs
  • Formulated with the highest quality glucosamine, chondroitin, and ASU for further joint health support
  • Helps block enzymes in joints that break down cartilage and supports reparation and regeneration of new cartilage


Keep bottle out of reach of children.

See all items by Nutramax

  • Item Number
  • Brand
  • Breed Size
    Large Breeds, Giant Breeds
  • Lifestage
  • Made in
    United States
  • Supplement Form
    Chewable Tablet

Nutritional Info


Each Soft Chew Contains: Glucosamine Hydrochloride* 99% (900 mg), Sodium Chondroitin Sulfate* (Low Molecular Weight) (350 mg), Avocado/Soybean Unsaponifiables* (Asu) Powder (90 mg). Dasuquin Chewable Tablets In Formulations Containing MSM (Methylsulfonylmethane). Dasuquin with MSM Contains 400 mg MSM for Small to Medium Dogs and Dasuquin with MSM Contains 800 mg MSM for Large Dogs. Reported On A Hydrous Basis. Standardized to Contain A Minimum of 30% of Avocado/Soybean Unsaponifiables.

Feeding Instructions

Weight Initial Daily Feeding (tablets) Maintenance Daily Feeding (tablets)
60 - 120 lbs 2 1

Allow 4 - 6 weeks initially to note a response, though some dogs may respond sooner. If desired, the number of tablets may then be reduced to a maintenance level. The maintenance level can also be used long-term in healthy dogs to help support their joints. An individual dog’s needs may vary. To provide extra support to the joints, dogs on a maintenance level can be increased to the initial level as needed, e.g., on weekends or other times when they are more active. Store in a cool, dry area out of direct sunlight. Keep lid tightly secured to ensure freshness.

Frequently Asked Questions

What is Dasuquin® for Dogs?

Dasuquin from Nutramax Laboratories Veterinary Sciences, Inc. is a joint health supplement for dogs that goes beyond standard glucosamine supplements. It contains NMX1000®* avocado/soybean unsaponifiables (ASU), green tea extract (EGCG), FCHG49®* glucosamine hydrochloride, and TRH122®* low molecular weight chondroitin sulfate in a chewable tablet and soft chew. It is a comprehensive joint support supplement.

What role do the glucosamine hydrochloride and low molecular weight chondroitin sulfate play?

The combination of the trademarked FCHG49 glucosamine hydrochloride and TRH122 low molecular weight chondroitin sulfate supports cartilage matrix production and helps block enzymes in joints that break down cartilage. These ingredients together have been shown in published studies to protect joint cartilage better than either ingredient alone. A greater than additive effect, known as a “synergistic” effect, on cartilage cells was seen using this glucosamine and low molecular weight chondroitin sulfate together.

What is ASU, and how does it work?

ASU stands for avocado/soybean unsaponifiables, an ingredient concentrated directly from avocados and soybeans that is used for joint health. ASU has been shown to improve joint function and comfort levels. Studies using cartilage cells have shown that ASU lowers the expression or production of several compounds involved in the process of cartilage breakdown in joints. ASU complements the positive effects of the other active ingredients in Dasuquin. The glucosamine in Dasuquin is synergistic with low molecular weight chondroitin sulfate and has been shown in cartilage cell studies to be synergistic with ASU. Of note NMX1000 avocado/soybean unsaponifiables, FCHG49 glucosamine hydrochloride and TRH122 low molecular weight chondroitin sulfate together were shown in cell studies to be better than the combination of glucosamine and chondroitin sulfate alone at inhibiting expression of several agents involved in the breakdown of cartilage. The highly absorbable green tea extract (EGCG) is rich in antioxidants, which have a positive effect on cartilage as well as on overall body defenses.

How do I know if my dog needs Dasuquin?

It may be a good time to ask your veterinarian about Dasuquin if you notice that your dog slows down during walks, does not get up easily, or is reluctant to climb stairs or jump into the car. Your veterinarian will examine your dog to determine if he/she could benefit from Dasuquin. If your veterinarian has already recommended Dasuquin, the sooner it is started the more opportunity your pet will have to respond. Your veterinarian may also suggest using Dasuquin as a protective measure. This can be important for maintaining an active life for many dogs, especially large breeds and working dogs of all sizes. Dasuquin may also be used to help support cartilage following joint surgery.

What should I be looking for when giving my dog Dasuquin?

Observe your dog closely, and notice whether your dog seems more comfortable doing those activities he seemed reluctant doing or had some trouble doing previously. Changes in your dog’s comfort level may occur gradually. Allow time for your dog to respond. It may take 4 - 6 weeks, though some dogs may respond sooner.

What else can I do for my dog?

Your veterinarian may recommend exercise, which is important for optimal joint function as well as weight control and the overall health of your pet. Joint movement is needed to circulate fluid around the cartilage as well as to bring nutrients and to remove waste products. It has been shown that when joints are immobilized, cartilage structures deteriorate at a rapid rate. You should ask your veterinarian, but in most cases, moderate exercise is recommended. Walking on sand or another soft surface or even swimming will help circulate needed nutrients and reduce excessive stress to the cartilage. It is important not to push your pet but to exercise at a comfortable pace.

Are there any safety concerns in dogs with Dasuquin use?

While sensitivity to avocados has been reported in a few dogs, taking Dasuquin tablets is not the same as eating whole avocados. The ASU in Dasuquin has been evaluated in a safety study in dogs, and no adverse effects were noted from administration. There are no known contraindications or known interactions between Dasuquin and any drug or supplement.

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  • Miracle for my older dog

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    I originally bought a smaller bottle at my Vet's office for my 11 year old dog. She's 90 pounds and has arthritis and wasn't moving well. Dasuquin made a very big difference in the quality of her life. She runs, plays and gets up from sitting or laying down like she did when she was years younger. When my bottle ran out, I checked to see if Chewy.com had it and found that I was able to buy twice the amount for the same price I paid at my vet's office. I'm now a chewy.com customer!

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  • $6000 pup maintained by these pills

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    My dog had elbow displagia in both his front legs. He also had a slipped tendon in his hind leg. These were both genetic issues. After all his surgeries done by an orthopedic specialist (which who knew there was such a thing for a dog) he was doing much better. The doctor told me to give him Dasuquin for the rest of his life and it would help him tremendously. I kept forgetting to order because he was doing good and still young at 18 months old. I finally ordered these and WOW... such a huge difference in him. My pup just wants to play all the time and is moving so much better than he was already. I feel awful for not getting these for him sooner!

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  • Our 12 year old Princess is running again!

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    This product has made a huge difference in our dog's joint health. Princess was getting to the point where she was having trouble getting up the stairs and trouble getting up after lying down for a while. It broke my heart to see her suffer like this. So at her last visit to the Vet, he recommended Dasuquin with MSM and after a few weeks Princess was back to her old self. She now has no problem getting up the stairs, no problems getting up after lying down and is even running and playing again! Thank you Dasuquin!

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  • Fabulous Product

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    I use Nutramax Dasuquin for my 2 dogs. My babies are considered to be senior citizens. This 9 year old considers himself to be a puppy, he loves to run and to chase the football. But every now and then his age starts to show. But slowing him down, and him being on the Dasuquin, has made a difference in his life. It helps to add a little bit of quality to his life, so that he can continue to do the things that he loves and enjoys.

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  • Bippy likes her Pill

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    Our vet recommended this product after Bippy injured her back knee. She sometimes carries that foot, but she does use it when she walks in the house. Pricing of this product is cheaper with Chewy than with my vet. The bottle they had was less quantity for about the same money. After my second cup of coffee every morning, I tell her, "it is time for your pill" and she looks in the direction of where I keep the bottle. She eats it well and even scoffs up any pieces she might drop. I sure am glad she likes her pill because she may be taking this for a while.

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  • So much better!!

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    Our 11 yr old Shepherd/Great Dane mix was started on these by his vet. Coupled with concentrated fish oil these tabs are a fountain of youth for him! He is so much less stiff and able to keep up with his 1 yr old lab brother

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  • You have to try this

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    My three yo heeler had a slight limp and my vet recommended this as the treatment to some soft tissue damage in his elbow. Hes a completely different dog. No limp and lots more energy. Amazing product. I recommend everyone try it.

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    By on

    My sweet almost 7 year old Airedale has been on Dasuquin since she was a puppy. My vet recommended it and suggested that we use it as lifetime maintenance rather than wait until there was a possible issue and actual need later in life. I think this, and her big personality, has contributed to her acting like she is still a puppy !!!! She gets one every day after breakfast. Highly recommend.

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  • Seems to help/work

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    Our 3 year old English Lab has been limping on and off when ever he plays really hard for the last year or so. Vets can't find anything. Started him on this for the last month or more and it seems to help.

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  • Recommended by my dog's orthopedic surgeon

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    He recommended this for my 3 year old GSD who fortunately has no orthopedic issues so far. He think it can help prevent them. I toss a tablet into his food and he eats it.

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