Zymox Enzymatic Dog & Cat Shampoo

By Zymox
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12-oz bottle
  • 12-oz bottle
  • 1-gallon bottle
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The first line of defense against infectious microbes is the skin. Zymox Shampoo provides an effective way to protect this natural barrier without being irritating or drying. Only the mildest plant surfactants are used and the enzymes have anti inflammatory properties to calm the skin. The LP3 Enzyme System with the addition of Vitamin D3 helps relieve surface irritations and hydrate the skin. The shampoo contains no harsh detergents, chemicals or petroleum bi-products and features a pleasant, mild fragrance.

Key Benefits

  • Effective way to clean, hydrate, and protect without irritating or drying the skin.
  • LP3 Enzyme System acts like a shield against surface microbes and Vitamin D3 helps hydrate the skin.
  • Doesn't contain harsh detergents, steroids, or petroleum by-products
  • Gentle enough to use on puppies.


For external use only. Avoid contact with eyes. If condition worsens or does not improve in 2-4 weeks, discontinue use and consult your veterinarian. Keep out of reach of children. Store at room temperature.

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  • Item Number
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  • Made in
    United States


Wet animal thoroughly with water. Apply ZYMOX Shampoo directly. Wash entire animal, concentrating on problem areas. Leave lather on 3 to 5 minutes then rinse. Repeat if needed. Use twice weekly or until symptoms subside. Follow with ZYMOX Conditioning Rinse for best results.

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Customer Reviews

Rated 4.6 out of 5 by 48 reviewers.
Rated 5 out of 5 by This shampoo is great in so many ways This shampoo smells so good and makes my dogs hair so silky and smooth. It is great for any skin irritations and dry spots. October 27, 2016
Rated 5 out of 5 by Great shampoo Our groomer recommended Zymox and it works so well. Our dog has stopped itching. October 17, 2016
Rated 5 out of 5 by Definitely works! My dog is allergic to everything and most shampoos make his issues even worse. I use Zymox ear solution for his ear infections and I didn't expect any less from their shampoo. It helped his skin AND smells so much better than any medicated shampoo I've used on him. His skin looks great now October 7, 2016
Rated 5 out of 5 by Great price for shampoo for sensitive skin. My Holistic vet sold me my first bottle of this shampoo for my immune compromised Newfie who would always break out in a nasty hot spot right after grooming even when a "hypo allergenic" product was used. Since it takes the entire bottle to bathe, Dewey the reduced price at Chewy was a welcome relief. (The groomer whether I bring my own shampoo or not is over $100 with tip.) October 1, 2016
Rated 5 out of 5 by Love this product The Zymox shampoo and conditioning rinse were recommended to me by a customer service representative at Chewy's. I am so thrilled with the results that I had to write a review. We had a dog who was suffering with itching skin with cause unknown. We used these products as instructed and they helped him so much. He is no longer scratching and his coat looks beautiful and smells so good. He was on a very low fat diet for chronic pancreatitis and we did put him on a different food that was still low fat but not as low. We feel the shampoo and rinse have made his life so much better and ours too!! Highly recommend September 16, 2016
Rated 5 out of 5 by Great product! I bought this shampoo because my dog would not stop itching. He was so itchy to the point where he was biting his skin. I've only used this shampoo once since I purchased it and I've noticed a HUGE difference. It has helped immensely. Yogi's itching has almost completely stopped. The shampoo has a nice mild smell and lathers great. After years of trial and error, i've finally found the perfect shampoo for his sensitive skin. I'll definitely be buying this in the gallon size next time. September 16, 2016
Rated 5 out of 5 by Love Zymox!!! My adopted dog has had chronic skin issues/infections/allergies and not responding to the typical treatments...This shampoo and conditioner have been the BEST help to keep symptoms under control...the conditioner also acts as a lotion to soothe and is not greasy and his coat (hair) is free from matts.. Everynow and then, I have to have a white vinager rinse (if fungus) and or Dakins solution (bleach solution) added to bathing, but, this stuff is wonderful! Thank you Zymox! September 8, 2016
Rated 4 out of 5 by good product Only used once, but so far his coat look great. However has not eliminated the scratching but has not got worse. Perhaps will have more effect when used more often. August 29, 2016
  • 2016-10-31 T07:01:08.915-05:00
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