Zymox Enzymatic Dog & Cat Shampoo

By Zymox
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12-oz bottle
  • 12-oz bottle
  • 1-gallon bottle
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The first line of defense against infectious microbes is the skin. Zymox Shampoo provides an effective way to protect this natural barrier without being irritating or drying. Only the mildest plant surfactants are used and the enzymes have anti inflammatory properties to calm the skin. The LP3 Enzyme System with the addition of Vitamin D3 helps relieve surface irritations and hydrate the skin. The shampoo contains no harsh detergents, chemicals or petroleum bi-products and features a pleasant, mild fragrance.

Key Benefits

  • An effective way to clean, hydrate, and protect without irritating or drying the skin.
  • Developed with only the mildest plant surfactants and the enzymes have anti-inflammatory properties to calm the skin.
  • The LP3 Enzyme System with the addition of Vitamin D3 helps relieve surface irritations and hydrate the skin.
  • This shampoo doesn’t contain any harsh detergents, chemicals or petroleum bi-products for a gentle wash.
  • Features a pleasant, mild fragrance and is delicate enough for puppies.


For external use only. Avoid contact with eyes. If condition worsens or does not improve in 2-4 weeks, discontinue use and consult your veterinarian. Keep out of reach of children. Store at room temperature.

See all items by Zymox

  • Item Number
  • Lifestage
  • Made in
    United States


Wet animal thoroughly with water. Apply ZYMOX Shampoo directly. Wash entire animal, concentrating on problem areas. Leave lather on 3 to 5 minutes then rinse. Repeat if needed. Use twice weekly or until symptoms subside. Follow with ZYMOX Conditioning Rinse for best results.

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Customer Reviews

Zymox Enzymatic Dog & Cat Shampoo is rated 4.7 out of 5 by 56.
Rated 5 out of 5 by from Great for dogs with allergies My dog has seasonal allergies. The scratching and licking of paws. This shampoo is thick and seems very soothing. I use this along with the conditioning rinse. We had gone to the vet and she gave us a shampoo that once I started to google it, had so many side effects. No thanks. I feel comfortable using this shampoo and would recommend you give it a try if your dog had allergies.
Date published: 2017-02-06
Rated 5 out of 5 by from THis is what your dog needs!! MY 7yr.old male yorkie has been having an skin issue that started last summer and has only gotten worse.O results with the vet,until I found this!! I had tried many other products, as well as DIY. but no relief. The first use gave him immediate relief and the results were more than I expected along with the ENZYMATIC RINSE that you can leave on and use on dry coat.Both products smell "WONDERFUL"NO MORE SEARCHING and spending $$$$ on products that did not work. Started my 2 yorkies on the Vet's Best Seasonal Allergy as well for both kid's just in case. I crush 1 tab. and give each 1/2 in their food once per day. I RECOMMEND This because it WORKS!!!
Date published: 2017-02-15
Rated 5 out of 5 by from The Zymox Shampoo & Conditioner are EXCELLENT !! I have purchased and used Zymox shampoo, leave in conditioner, ear drops and ear wash... these products are made in the USA and the first that have worked so well on my Red-Tick Coonhound, who had itching on both his body and ears... (his body itch did not come from food allergy, fleas/ticks or mites or hot spots. He never had a rash... just an itch, between Mid October thru end of April - and Not outside. So it was difficult to pinpoint his particular problem..but Zymox Works !! I have made several purchases and All have been great products. Love the fact of all the ones I purchased were Made in USA !! Chewy shipping is Lightening Fast... and packaged for the safety of the products...
Date published: 2017-02-20
Rated 4 out of 5 by from Good quality even though I'm biased bc my aunt works for this brand, this shampoo feels like good quality shampoo. I also like the way it makes my pit smell.
Date published: 2016-12-30
Rated 5 out of 5 by from Fantastic! This shampoo is awesome. Not only does it smell great, it thoroughly cleaned my fur babies coats and helped relieved their itchy skin.
Date published: 2016-12-27
Rated 5 out of 5 by from This shampoo is great in so many ways This shampoo smells so good and makes my dogs hair so silky and smooth. It is great for any skin irritations and dry spots.
Date published: 2016-10-28
Rated 5 out of 5 by from Works wonders!!! I have a dog with horrible allergies this time of year and can't quite figure out what it is that irritates her skin so much! She's constantly nibbling, licking and itching. She had nickle-quarter sized welts, little red bumps and sores from her chest down to her belly. Vet just gave us a spray to use that never seems to help and told us to give her Benadryl. Nothing seemed to help get rid of these sores, So I did research on shampoos and found this one. After a couple washes with this product the welts have come down & the sores have been getting much better. We are still trying other things to help her out but I will defiantly be ordering this again! Kind of in a way has a black locorish smell to it In a clean way.,. Hard to explain but would for sure recommend others to try.
Date published: 2015-06-17
Rated 5 out of 5 by from Love the smell. I bought this and the creame rinse. I absolutely love the smell and it leaves my dog smelling fresh longer than perfumed shampoos. My dog's skin and coat is healthy as well. She gets a bath each month and haven't had any problems. I would repurchase when I run out and have no plans of using any other shampoo and conditioner.
Date published: 2016-12-11
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