Simparica

Keep biting pests from plaguing your pup with a prescription flea and tick medication. Chewy carries several types of prescription flea and tick treatment, including [topical](https://www.chewy.com/b/topical-treatments-11565) and [oral flea & tick medication](https://www.chewy.com/b/oral-treatments-11564), as well as combination medications that prevent heartworms and kill common parasites, too. 

Before you buy prescription flea & tick medication online, be sure to research all your options. The best flea and tick medicine will be easy to administer, suited to your dog’s lifestyle and effective for the climate you live in. Your vet can advise you on whether you need prescription flea and tick pills, a prescription topical product, or a non-prescription flea and tick treatment. If you have a younger dog, you should talk to your veterinarian about prescription flea & tick medicine for puppies and whether it would be a good choice for your furry friend. 

Prescription flea and tick topical treatments are easy to apply and can provide continuous protection that lasts a month or more. Many are also water-resistant, so they won’t interfere with regular bathing and grooming. Several prescription flea pills can offer long-lasting pest deterrence that’s water-friendly, too. Other flea control options include flea shampoos that let you wash annoying pests away, dog flea and tick sprays that kill on contact and yard treatment sprays that get to fleas before they can jump on your pup. 

You can also choose combination products that combine [heartworm medicine](https://www.chewy.com/b/heartworm-11562) with prescription oral flea and tick medication in one dose. The [Chewy pet pharmacy](https://www.chewy.com/b/pharmacy-2515) has many of the medications your vet might prescribe for your pets, including [flea & tick medication for cats](https://www.chewy.com/b/flea-tick-11591) and other [prescription dog medicine](https://www.chewy.com/b/dog-pharmacy-11561) for a variety of ailments. Shop our great selection of prescription flea and tick medications and get everything you need to help your best friend live an itch-free life!

Get dog flea and tick medication prescriptions online at Chewy Pharmacy by visiting your vet and talking about flea and tick control options. Your vet can then write you a prescription for the product and dose what’s appropriate for your pup. Then, go online and add the prescribed product to your cart. At checkout, you can add your dog’s info and vet contact information so Chewy can verify the prescription on your behalf. That’s all you need to do to order your prescription medications from Chewy!

How do I get dog flea and tick medication prescriptions online at Chewy Pharmacy?

The best prescription flea and tick treatment will vary by the age, health, lifestyle and habits of your dog and can best be determined by your vet. Popular brands include Comfortis, Advantage Multi, Simparica Trio, Revolution and Credelio, but there are many others that may uniquely suit your situation. Many come as once-a-month topicals or chewable tablet doses for easy use. Check out some of the great reviews on our site to learn more about which ones might be best for your bestie!

What prescription dog flea and tick treatment is best?

The difference between over-the-counter and prescription flea and tick medication is that you need a vet to prescribe the latter. The ingredients in prescription medications are more carefully controlled and regulated, and therefore, dosing may be more precise and possibly safer. Many prescription treatments are more effective than over the counter products, as well. Your vet can give you the most up-to-date information on what works well, what’s safest and what’s right for your pup.

What is the difference between over-the-counter and prescription dog flea and tick medication?

Dog flea treatments work in different ways depending on which product you use. Prescription oral and topical flea treatments usually work by depositing chemicals into the sebaceous glands of your dog. These chemicals then spread out over the body as your dog’s coat lubricates itself, neutralizing fleas and ticks by acting on their central nervous system. This prevents them from feeding on your pup and causing irritation, itch, parasites and disease.

To set up Autoship for your prescription dog medicine, select the Autoship option at checkout and choose how often you want it delivered. Once you set up Autoship, you can cancel or change your deliveries any time you want. You must have a valid prescription or remaining refills on file for Autoship pharmacy deliveries to occur. If we do not have a prescription, or if your prescription is expiring soon, one of our team members will reach out to your vet to obtain all the necessary information. You’ll always have your prescription dog medicines on hand when you choose Autoship from Chewy!

How do I set up Autoship for my prescription dog medicine?

Flea & Tick

Prescription Flea & Tick Medicine for Dogs

Simparica for Dogs

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Shop Chewy for the best deals on Simparica for Dogs and more with fast free shipping, low prices, and award-winning customer service. Read ratings and reviews so you can find the right Simparica for Dogs for your pet.

Simparica for Dogs (Free Shipping) | Chewy

Pills & Chewables

True

Autoship & Save Eligible

Extra Small & Toy Breeds

Small Breeds

Medium Breeds

Large Breeds

Breed Size

Fleas

Ticks

Health Condition

Advantage Multi

Boehringer Ingelheim

Bravecto

Comfortis

Credelio

Elanco

Heartgard

Interceptor Plus

Merck

NexGard

Revolt

Revolution

Selarid

Senergy

Sentinel

Sentinel Spectrum

Simparica Trio

Trifexis

Virbac

Zoetis

Brand

[50,*]

Price

[4,5]

[3,5]

[2,5]

[1,5]

Customer Rating

Simparica Chewable Tablet for Dogs, 44.1-88 lbs, (Green Box), 6 Chewable Tablets (6-mos. supply)

Simparica Chewable Tablet for Dogs, 11.1-22 lbs, (Orange Box), 6 Chewable Tablets (6-mos. supply)

Simparica Chewable Tablet for Dogs, 22.1-44 lbs, (Mint Box), 6 Chewable Tablets (6-mos. supply)

Simparica Chewable Tablet for Dogs, 5.6-11 lbs, (Purple Box), 6 Chewable Tablets (6-mos. supply)

Simparica Chewable Tablet for Dogs, 88.1-132 lbs, (Brown Box), 6 Chewable Tablets (6-mos. supply)

Simparica Chewable Tablet for Dogs, 2.8-5.5 lbs, (Yellow Box), 6 Chewable Tablets (6-mos. supply)

Simparica for Dogs

Simparica Chewable Tablet for Dogs, 44.1-88 lbs, (Green Box), 6 Chewable Tablets (6-mos. supply...

Simparica Chewable Tablet for Dogs, 11.1-22 lbs, (Orange Box), 6 Chewable Tablets (6-mos. suppl...

Simparica Chewable Tablet for Dogs, 22.1-44 lbs, (Mint Box), 6 Chewable Tablets (6-mos. supply)...

Simparica Chewable Tablet for Dogs, 5.6-11 lbs, (Purple Box), 6 Chewable Tablets (6-mos. supply...

Simparica Chewable Tablet for Dogs, 88.1-132 lbs, (Brown Box), 6 Chewable Tablets (6-mos. suppl...

Simparica Chewable Tablet for Dogs, 2.8-5.5 lbs, (Yellow Box), 6 Chewable Tablets (6-mos. suppl...

Category

Breed Size

Health Condition

Brand

Price

Customer Rating