Frontline Gold Flea & Tick Treatment for Large Dogs (45-88 lbs)

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3 treatments
  • 3 treatments
  • 6 treatments
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Frontline Gold for Dogs doesn’t just kill adult fleas and ticks, but also slays the next generation of flea eggs and larvae. Even faster than Frontline Plus, Frontline Gold starts working within 30 minutes and lasts for 30 days! It works because of two, tough killing ingredients. The first, fipronil, kills adult fleas and ticks. The second, (S)-methoprene, attacks flea eggs and larvae. They work together to kill all month long. Plus, it breaks the flea life cycle. By also destroying the next generation of flea eggs and larvae, Frontline Gold gives you the power to help prevent a flea infestation on your pet. Frontline products are highly recommended by veterinarians for flea and tick control for dogs.

Key Benefits
  • Provides fast-acting, long-lasting treatment and control from the makers of Frontline Plus.
  • Kills adult fleas, ticks, chewing lice, mites, and flea eggs and larvae that may transmit Lyme disease.
  • Safe for use on dogs and puppies 8 weeks or older between 45-99 pounds.
  • Kills flea eggs and larvae to stop existing infestations and prevent the establishment of new infestations.
  • Easy to apply and waterproof 24 hours after application.

Active Ingredients

  • Fipronil
  • (S)-methoprene
  • Pyriproxyfen

See all items by Frontline Gold

  • Item Number
  • Brand

    Frontline Gold

  • Dosage Measure

    30 days

  • Brand


  • Breed Size

    Large Breeds

  • Lifestage

    Adult, Puppy, Senior

  • Health Condition

    Fleas, Ticks

Recommended Dosage

1 applicator

*Remove one applicator tube from the package and hold in an upright position pointed away from your face. *Twist dispensing tip clockwise about 1/2 turn while pushing down to break the tube's seal. Do not remove the dispensing tip. Position the dispending tip on the dog's back between the shoulder blades. *Use the dispensing tip of the tube to part the dog's hair so that the product will be applied at skin level. *Begin squeezing out the contents of the tube to form a stripe as you move from the shoulder blades along the dog's back to the base of the tail. *Repeat every month.


Where do these new fleas come from?

Numerous hosts (including feral cats, opossums, raccoons, and other wildlife species) leave behind flea eggs wherever they go, including your yard. These outdoor flea infestations are often the primary source of the fleas that your pets pick up. Outdoors, developing flea stages can be found in areas protected from sunlight, so some of their favorite places include:

  • Sheds
  • Garages
  • Under porches or decks

How long will a flea infestation in the home last?

Flea eggs, larvae, and pupae in the environment continue to develop and emerge as new fleas (even after your pet has been treated with a flea control product). It can take weeks to months for this already established infestation to be controlled.

What else can I do to reduce the flea population in my home?

Regular use of an appropriate Frontline Gold brand product on your pet may reduce flea infestations in the home. For best results, use Frontline Gold brand products as part of a comprehensive flea treatment plan, which includes coordinated treatment of the home, yard and pet. Vacuum floors, carpets and furniture – especially in areas where an infested pet has spent a lot of time, because that is often where many flea eggs will be found. Wash pet bedding and other fabrics in hot water.

Why do I still see fleas on my pet after applying Frontline Gold?

There are two main reasons:

  • Fleas can jump onto your pet at any time (see where do new fleas come from), and these are not killed instantly.
  • Frontline Gold brand products are designed to kill any new fleas quickly and prevent their ability to reproduce. Frontline Gold kills fleas by overstimulating the flea nervous system, and hyperexcited fleas may move to the top of the haircoat before they die. So seeing fleas on top of the haircoat after applying Frontline Gold can be an indication that the product is working.

How does Frontline Gold for Dogs and Frontline Gold for Cats work?

After being applied, Frontline Gold for Dogs and Frontline Gold for Cats spreads all over the treated animal’s body and is stored in the sebaceous glands under the surface of the skin. From these glands, it is continually wicked through the hair follicles onto the skin and haircoat for a month or more.

Should I apply Frontline Gold for Dogs to ALL the dogs and Frontline Gold for Cats to ALL the cats in my household, even if they are indoor-only?

Absolutely. If you don’t treat every dog and cat, the untreated pets can continue to harbor fleas that will lay eggs, preventing the infestation from being cleared. Even if the dog or cat never goes outdoors, people may bring fleas into the home.

How often should I apply Frontline Gold brand products to my pets?

For continuous protection, apply an appropriate Frontline Gold brand product every 30 days as directed. Consistency is key.

Can I bathe my pet while using Frontline Gold?

Yes. Frontline Gold brand products remain effective for 30 days, even if your pet swims or is bathed. You may bathe your pet 48 hours after application. ONLY use a shampoo formulated for your pet and recommended by your veterinarian.

Customer Reviews
6 Reviews 6 Reviews 2.8 out of 5 Stars

67% Recommend

67% of reviewersrecommend this product

2.8 / 5

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  • Frontline gold

    By on

    We have had fleas for months!!! We details vacuum everyday plus comb and treat our pets every day! This had become very stressful. I spoke with my vet she said that if you are using frontline it needs to be applied every 3 weeks so there is countious protection. I have spent 100’s of dollars and putting so much stress on our family and our pets. I finally started to ask around, and someone recommend the collar that last 8 months. I switch to that and it was a legit game changer! less then a week our fleas are GONE! I have even been checking the pets weeks later for any stranglers and they are GONE! Stay away from frontline it DOESNOT work!

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  • Die fleas, die!!

    By on

    Last month I used Advantix, this month used Frontline Gold, nothing it seems is going to kill all of the fleas. But much better results for us with the Frontline this go round.

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  • Doesn’t work

    By on

    I think fleas in the area are resistant to frontline now, big waste of money for me. Wouldn’t recommend wasting the money if regular frontline doesn’t work either, try the Seresto flea collars.

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  • Killed the Fleas

    By on

    Used the Frontline Plus and it didn’t work! Waited a month and used this Gold. Fleas were dead in 30 minutes. Great!

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  • It worked for my dogs

    By on

    I used the Frontline gold and it worked pretty fast also and now my dogs are no longer itching

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  • Did not work

    By on

    Put it on just as directed, still have fleas and it's been a week.

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