Frontline Plus Flea & Tick Spot Treatment for Extra Large Dogs, 89-132 lbs

By Frontline Plus
Rated 4.3043 out of 5 stars
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About This Item

  • Promotes a fast-acting and long-lasting protection from fleas and ticks.
  • Formulated with two active ingredients to help disrupt the flea life cycle.
  • Kills adult fleas, flea eggs, flea larvae, chewing lice, and ticks.
  • Simply apply once a month.
  • Designed for a waterproof protection after 24 hours.
Play Video: Learn More About Frontline Plus From Our Team of Experts
Learn More About Frontline Plus From Our Team of Experts

Important Information

Fleas rise to the top of your pet's coat as they die, so consider it a triumph if you start seeing more fleas at first, after treating your pet. If you’re still seeing fleas after application, it may be because your pet has picked up new fleas from the environment, which may include other pets, surfaces and outdoor areas. It may take up to 90 days to break the entire flea life cycle. Additionally, you should also treat sources of new fleas (i.e., carpet, yard, etc.) to ensure complete flea control.



About FRONTLINE Plus for Dogs

#1 Name in Flea and Tick Protection*

FRONTLINE Plus is proven flea and tick protection that has been trusted by pet parents for over 20 years.** Just one dose of FRONTLINE Plus provides fast-acting protection that lasts for a full 30 days.

Break the Flea Life Cycle

FRONTLINE Plus contains fipronil, which kills adult fleas, as well as (S)-methoprene, which kills flea eggs and larvae. Together, these active ingredients break the flea life cycle, prevent future infestations, and provide continuous protection for a full month.

Protect Your Dog Here, There and Everywhere

Fleas and ticks can be found at the park, the lake and in your own backyard. That’s why it’s important to keep your dog protected month after month.

The #1 Name

FRONTLINE is the #1 name in flea and tick protection.*

Long-Lasting Protection

One dose of FRONTLINE Plus for Cats lasts a full 30 days.

Fast-Acting Formula

Once applied to your cat, this powerful formula kills fleas, ticks and chewing lice on contact.

Waterproof

FRONTLINE Plus is waterproof 24 hours after application.

Trusted Protection

FRONTLINE Plus has been trusted by pet parents for over 20 years.**

Effective for Puppies

FRONTLINE Plus for Dogs can be used on puppies as young as 8 weeks and weighing at least 5 lbs.

For Dogs Big and Small

Choose from four formulas—Small 5-22 lbs., Medium 23-44 lbs., Large 45-88 lbs., and Extra-Large 89-132 lbs.

Formulation Available for Cats

Protect your cats with FRONTLINE Plus for Cats!

Pests Can Be a Year-Round Threat

Flea infestations usually begin 6-8 weeks before you ever notice a flea on your dog, and once your home is infested, it can take up to 90 days to eliminate all stages of the flea life cycle. Protecting your dog with FRONTLINE Plus monthly, year-round can help prevent reinfestations.

Protect Year-Round with Autoship

Sign up for Autoship today and save on FRONTLINE Plus. You’ll get a discount on every order of FRONTLINE Plus, and you can rest easy knowing that you’ll never run out of proven flea and tick protection.

The Mission

Boehringer Ingelheim, the maker of FRONTLINE Plus, is committed to enhancing the well-being of pets and supporting the animal health community through science and innovation. No animal should have to suffer a preventable disease, which is why Boehringer Ingelheim develops products like FRONTLINE Plus.

About FRONTLINE Plus

FRONTLINE Plus is the #1 name in flea and tick protection.* It’s formulated with two active ingredients that kill fleas and ticks and prevent new flea infestations from developing. FRONTLINE Plus is waterproof 24 hours after application, lasts for a full 30 days and has formulations available for dogs and cats. With FRONTLINE Plus, you can take your pet everywhere.

Shop Frontline

* Data on file at Boehringer Ingelheim

** Data on file at Boehringer Ingelheim

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Top IngredientsActive Ingredients : Fipronil 9.8% , (S)-methoprene 8.8%.Active Ingredients : Fipronil 9.8% , (S)-methoprene 8.8%.Active Ingredients: Fipronil 9.8%, (S)-Methoprene 8.8%.Active Ingredients: Fipronil 9.8%, (S)-Methoprene 8.8%.Active Ingredients: Imidacloprid 8.80%, Permethrin 44.00%, Pyriproxyfen 0.44%...
LifestageAdultAdult, Puppy, SeniorAdultAdultAdult, Puppy, Senior
Breed SizeLarge BreedsMedium Breeds, Large BreedsLarge Breeds, Giant BreedsMedium Breeds, Large BreedsSmall Breeds, Medium Breeds

Questions & Answers

19 Customer Questions


How long should I wait to apply Frontline Plus before or after a bath??
Answer by ChewySep 24, 2018
If FRONTLINE Plus is to be applied after a bath, make sure your pet is completely dry before application. FRONTLINE Plus remains effective for 30 days, even if your pet swims or is bathed. After application, keep your pet from getting wet for 24 hours.

How soon after applying this product should we expect to find no live fleas on our dogs? If we are still finding live fleas, how soon is it safe and advisable to apply a second treatment?
Answer by ChewyJul 11, 2017
The Frontline Plus Flea & Tick Treatment for Dogs will begin working within 12 hours against adult fleas and 48 hours against lice upon application. It's advised to use one treatment per month and not to use it multiple times within 30 days.

does this also repel mosquitoes
Answer by ChewyJun 17, 2017
This product does not repel mosquitoes.

Where is this Frontline made?
Answer by ChewySep 11, 2018
We receive our products right from the manufacturer. Frontline plus is made in France.


ReviewsWrite a Review

4.3
Rated 4.3043 out of 5 stars
470 Reviews
88%
Would recommend to a friend
1
12.5532
13%
2
2.5532
3%
3
2.3404
2%
4
7.0213
7%
5
75.5319
76%

470 Customer Reviews



Rated 2 out of 5 stars
By Ecko on Jul 25, 2022

I hate fleas

Mom put this on me 11 days ago because I had fleas. She first tried another brand but that didn't kill my fleas. So she tried Frontline Plus. I still have fleas!! These little buggers are STILL crawling all over me and jumping onto the furniture and rugs. She vacuums constantly and uses other stuff on the furniture but I am sooooo disappointed that this did NOT kill my fleas in the 48 hours it said it would. Mom is afraid of using too many chemicals on me. She regularly brushes me and is going to bathe me again today. I hope that helps!! We are all tired of these little buggers!!


Rated 1 out of 5 stars
By frontline on Aug 5, 2022

garbage. does not work. waste of $ and lies.

DO NOT WASTE YOUR TIME BUYING THIS. does not work. I live in a wooded area so I have lots of critters around. I tried frontline on 3 of my dogs and another brand on 3 others. The ones who had frontline were covered in fleas and bites everywhere during the 30 day time frame. The others had none. I didn’t even give the frontline away. I threw them in the trash. Don’t order frontline. Go buy nexgard or bravetco!!


Rated 5 out of 5 stars
By works on Jun 27, 2022

Works Great

I was no longer able to use the pills due to my dog being diagnosed with epilepsy. My vet suggested I use this instead. Considering how terrible the ticks have been this year I have only found them crawling on my St. Bernard and none have attached. Worst part of this is the oily spot on the back for the day or 2 after.


Rated 5 out of 5 stars
By Rose on Apr 4, 2022

It works as describes!

We have used this product in the past with mediocre results. Recently we tried Soresto collars as Frontline didn’t seem to be working. Ironically, the Soresto collars didn’t seem to be working and it’s now flea season in our area. The day we put the Frontline on all our dogs, they all stopped itching! So good to know this still works! We will stick to this in the future if it continues working *fingers crossed*


Rated 5 out of 5 stars
By Meandthedog on Jul 17, 2022

great service

You have always been helpful and accommodating. Couldn't find anyone who would be better, that's for sure!


Rated 5 out of 5 stars
By Mary on Jul 28, 2022

Happy doggo

Never disappointed with the easy ordering, fast delivery and great service when I have to call


Rated 5 out of 5 stars
By Mary on Jun 2, 2022

Use it for years. Works great

have used this product for years and will keep using it. - It works - we have no problems fleas or ticks on our dogs. We have 2 Great Danes and won't use anything else.


Rated 1 out of 5 stars
By Delanie on Apr 24, 2022

Not working

My poor chief is infested still after the 4th month. Even through winter. I asked a vet and they recommended the seresto collar and yard treatment so I am switching.


Rated 1 out of 5 stars
By zuko on Jul 14, 2022

doesn’t work

Didn’t seem to kill or repel any fleas at all. I was rather disappointed


Rated 5 out of 5 stars
By Louisee on Apr 14, 2022

BUY this product now because it works well, price savings

Have been using this product for many years, for my cats and my dogs, it has made them a great non itch item that gives them rest, great product