HILL'S PRESCRIPTION DIET Gastrointestinal Biome Chicken Flavor Dry Dog Food, 27.5-lb bag - Chewy.com

Hill's Prescription Diet Gastrointestinal Biome Chicken Flavor Dry Dog Food

By Hill's Prescription Diet
Rated 4.8125 out of 5 stars
Veterinary Diet Item

$116.99Chewy Price
$111.14Autoship Price
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About This Item


  • This prescription formula is designed to support the bacteria in your dog's gut.
  • Utilizes Hill's ActivBiome Technology—a mixture of active fibers that may help improve regularity.
  • Encourages the release of postbiotics to support the GI tract and help break down food.
  • Works to promote regular, healthy stool and reduce the risk of future episodes.
  • Formulated by Hill's trusted nutritionists and veterinarians.

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Nutritional Information

Feeding Instructions


Play Video: Learn More About Hill's Prescription Diet From Our Team of Experts
Learn More About Hill's Prescription Diet From Our Team of Experts

About Hill's Prescription Diet GI Biome Food for Dogs

Hill’s GI Biome Diet

Hill’s Prescription Diet Gastrointestinal Biome dog food takes a different approach to digestive care. Each formula uses a specific blend of active fibers, known as ActivBiome+, to help your dog’s stomach break down food more efficiently and promote healthier stools and regularity. It also contains Hill’s S+OX Shield ingredients, formulated to promote urinary health.

Activate the Gut Microbiome

When it comes to canine digestive health, the balance between good and bad bacteria is key. Promoting the growth of good bacteria helps keep problematic bacteria in check and supports ongoing digestive well-being.

Know the Signs of Digestive Issues

If you notice vomiting, diarrhea or soft stools, straining, stomach gurgling, flatulence, appetite changes, lethargy or depression in your dog, it may be from digestive trouble. See your vet for more insight and see if changing foods can help.

Risk Factors

Many things can trigger digestive issues in your pup, including food sensitivities, inflammation and bacterial, viral or parasite infections. Your vet can help determine what’s causing the trouble and figure out how diet can play a role.

Veterinarian Recommended

Vets know what’s best for their furry patients, so knowing that they place their trust in Hill’s can give you peace of mind.

About Hill's Pet Nutrition

For more than 70 years, Hill's Pet Nutrition has helped enrich and lengthen the special relationship between people and their pets by putting their passion for the health and happiness of animals into everything they do. They even partner with shelters to provide Hill's food to more than 9 million shelter pets.
Shop Hill’s Pet Nutrition

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Top IngredientsChicken, Cracked Pearled Barley, Brewers Rice...New: Brewers Rice, Whole Grain Corn, Chicken Meal...Whole Grain Wheat, Whole Grain Corn, Chicken Meal...Potatoes, Potato Starch, Duck...Brown Rice, Brewers Rice, Pork Fat...
Breed SizeSmall Breeds, Medium Breeds, Large Breeds...Small Breeds, Medium Breeds, Large Breeds...Small Breeds, Medium Breeds, Large Breeds...Small Breeds, Medium Breeds, Large Breeds...Small Breeds, Medium Breeds, Large Breeds...
Special DietPea-Free, Veterinary Diet, Sensitive Digestion, With GrainVeterinary Diet, Sensitive Digestion, With GrainVeterinary Diet, Weight Control, With GrainGrain-Free, Gluten Free, Pea-Free, Veterinary Diet, Chicken-FreePea-Free, Veterinary Diet, With Grain
Food FlavorChicken, PoultryChicken, PoultryChicken, PoultryDuck, PoultryChicken, Poultry
Health FeatureDigestive HealthDigestive HealthWeight ManagementSkin & Coat HealthKidney Care

Questions & Answers

19 Customer Questions

How many cups are in a 16 lb bag of Hill's Biome dry dog food
Answer by LolaGJan 27, 2023
Each pound of this food is equivalent to 4.6 cups. The 8 pound bag contains approximately 36.8 cups. The 16 pound bag contains approximately 73.6 cups. The 27.5 pound bag contains approximately 126.5 cups.

Is this dog food made in the United States? Where are the ingredients sourced?
Answer by ChewyMar 15, 2021
Hills is manufactured in the United States. We source raw materials only from countries where there are reliable safety procedures in place, primarily in the United States, Japan, Canada, New Zealand, Australia and several European countries.

Does this food cause extra thirst?
Answer by ChewyNov 23, 2020
The manufacturer does not currently have any records on side effects like extra thirst. We recommend consulting your veterinarian if you are unsure about possible side effects, as they have an entirely different industry insight, and they can give you a second opinion based on both professional experience and research.

Asking for Great Dane breed - do you have information about the Calcium/ Phosphorus ratio? I didn't see it in the Guaranteed Analysis tab - thanks in advance
Answer by ChewyOct 16, 2019
This dry dog food formula has a calcium content of 1.18% and a phosphorus content of 0.68% on an dry matter basis.

ReviewsWrite a Review

Rated 4.8125 out of 5 stars
512 Reviews
Would recommend to a friend

512 Customer Reviews

Rated 5 out of 5 stars
By JanS on Jan 29, 2023

Miracle Food!

We have a 9 year old beagle. He developed issues when he was just a few months old. We have worked with nutritionists and tried every food under the sun. He can't even eat crunchy food; it destroys his system. We settled on home cooked chicken and rice plus veggies, vitamins, probiotics, apples, and digestive enzymes. That worked relatively well for years. Then a year ago we had to start cutting out foods one by one. He was back to bloody stool and getting up at all hours to go out. He was a mess. We managed on metronidazole but that started to mess with his system too. My vet suggested biome and I was so hesitant because we've tried so many things. We took about 2 1/2 weeks to transition completely but after the first day of just a tablespoon, we saw an improvement. Now he is having normal stool 4 times a day and he absolutely loves this food! Thank you Hills. Yes, expensive but nothing compared to all the vet visits, meds and torture our dog was going through. Please never discontinue this food. Thank you!

Rated 5 out of 5 stars
By Brianna on Jan 25, 2023

Miracle Food!

My dog Maggie is a Yorkie with the worlds most sensitive stomach. She would constantly be in the emergency vet with bloody stools, green stools, and yes even turquoise stools once! (no vet could explain it). After trying what felt like every food out there and constantly being at the vet and her in pain, this food came on the market. She has had PERFECT stools ever since. Not one trip to the ER. Worth every penny!!! We do the wet and dry formula! She will be on this food for her whole life.

Rated 5 out of 5 stars
By BellasMom on Jan 13, 2023

A Blessing

For 3 years Bella (13 yr Beagle girl)has been fighting clostridium and gastric problems. Diarrhea..marshmallow stools..gastritis etc. Round after round of antibiotics..low fat food she didn't like extra fiber and daily probiotics. Changed vets and after one more round of antibiotics and a visit to the emergency vet the day after Christmas my vet suggested a changeover to this food. Had to do a slow changeover to this food but after 24 hrs of only Hills she had her first solid stool in years. She loves this food. I add a little warm water to make a little gravy and feed it to her bit by bit. She is a food gobbler and that's not good for her. She still gets added probiotics as she is on a daily low dose tylosin because of the bacteria issues but we no longer have to add extra fiber to her food which never worked anyway. She is feeling much better. She even wants to play and enjoys her time outside. Vet said it doesn't work for all dogs and dogs with gastric problems often have to try different things to find what works but this has been a real blessing for us. Don't know how long we will be together as we are both elderly but this food gives her a better quality of life.

Rated 5 out of 5 stars
By Bridgette on Jan 25, 2023

Things are back to BETTER than normal

Hills RX Diet is great - I only wish I fed Biscuit this sooner. Not only has her tummy and GI system improved, but her overall well-being and dog attitude has improved too...which makes for a better life for all. This food is great - good for your dog and better yet, your dog will absolutely love it and eat it with gusto. It has been a lifesaver. Highly recommended and worth the price.

Rated 5 out of 5 stars
By Yooper on Jan 5, 2023

Great fd for GI issues!

My friend's corgi had problems w/GI issues, including bloody and soft stools, and has been using steroids and metronitazole to control this. Even w/steroids, every time she finished a course of metronitazole, the stool issues would return. She is currently going off steroids, as her liver enzymes increased, and we hope to discontinue metronitazole soon. Even w/metronitazole but w/o this food, her poops were soft, but as soon as we began this food they got firmer and darker (darker means more nutrients were being absorbed by her gut). We are just thrilled. This product is worth every penny.

Rated 5 out of 5 stars
By Sheri on Dec 30, 2022

Hills Gastrointestinal Biome

My precious Skye is my world! I praise God everyday for blessing me with her. Skye was on only Hills science 11+ small bites. As she will turn 15 Feb 6th, she was developing bouts of diarrhea. I started adding the biome to her diet a couple weeks ago. We have not had a loose bowel! I am struggling financially, and I know it is expensive. Please trust me it's worth it , for your loved friend and yourself! Love, Sheri and Skyegirl

Rated 5 out of 5 stars
By Jenn on Dec 26, 2022

Puppy diarrhea Lifesaver

My puppy has suffered GI symptoms for months. We did Bloodwork, tried Flagyl treatments multiple times, tried different diets, she even would throw up in the AM sometimes. The vet started her on Prilosec for the AM and then started her on this diet. She swore by it and said within 24 hours the diarrhea would go away. I was a bit skeptical because that seemed a bit extreme but it proved to be true! We have had her on this for a few weeks now and she hasn't had a diarrhea episode since she has been on this! Seriously a lifesaver for our poor GI doggo.

Rated 5 out of 5 stars
By Jessica on Jan 16, 2023

best food for my 1 year old French bulldog

We were struggling with my French bulldogs bowels for her first year of life. After multiple episodes of diarrhea our vet suggested this food. As advertised within 24 hours of a gradual shift, her poops started to form. We’ve had her on this food for 5 months now and we’ve had no bowel issues. Literally changed our lives!

Rated 5 out of 5 stars
By Tiffany on Dec 31, 2022

Miracle Food

I can’t recommend this food highly enough. As a puppy, my dog seemed to be sensitive to almost everything she ate. She’s been on this food for several months now and is now 1.5 years — not only has it resolved her day-to-day digestive issues, but it’s helped her build a stronger stomach in the long term. Given the nightmares I experienced the first few months I had her, I owe Hill my life. Pricey but worth every penny.

Rated 5 out of 5 stars
By BobsMom1 on Jan 10, 2023

Great products

Our pup was rescued and plagued with Giardia and other bacteria During treatment it was suggested by our vet that he may have food sensitivity as well This formula stopped his diarrhea and he loves it Thanks to Chewy for their excellent customer service and prompt shipping We are so thankful