Hydrocortisone (Generic) Cream 2.5%, 30-g

Prescription Item

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Hydrocortisone Cream 2.5% is a topical cream prescribed as an anti-inflammatory to treat redness, swelling, itching and other skin conditions. It works by blocking natural substances (histamines) that occur during an allergic reaction. This medication is also available in a 1% strength. Customers may receive this drug under the name Zymox.


Indicated to provide relief from itching caused by inflammation, seborrheic dermatitis, insect bites and other minor skin irritations.

Possible Side Effects

Due to reported effects on the stomach lining, Hydrocortisone can result in stomach ulcers. Never use it with non-steroidal anti-inflammatory drugs. As with other Hydrocortisone should be avoided when fungus infections, liver or kidney impairment or stomach ulcers are present. Other adverse effects are increased appetite, increased thirst, weight gain and dull hair coat. Muscle weakness, liver damage and behavioral changes can also occur.

Drug & Food Interactions

Hydrocortisone may interact with other medications. Consult with your vet to determine if other drugs could interact. Drugs may include aspirin, insulin, ephedrine, estrogens, non-steroidal anti-inflammatory drugs and certain diuretics.


Always wash hands after application or wear gloves when applying. Avoid contact with eyes.

NOTE: For Generic Medications, picture displayed may not depict actual product. Generic medications may vary from one order to the next by size, color and shape depending on manufacturer. Customers may receive the same drug under the name Zymox

This drug is FDA-approved for human use. However, it is common practice for veterinarians to prescribe such drugs for use in dogs and cats.

  1. Prescribing Information

See all items by Hydrocortisone

  • Item Number
  • Brand


  • Dosage Measure

    Use according to your veterinarian's instructions.

  • Generic Name


  • Common Brand Name(s)


  • For Use With

    Dogs & Cats

  • Product Form


  • Health Condition

    Skin Infections, Allergies, Atopic Dermatitis (Eczema)

  • Drug Type




Recommended Dosage

Use according to your veterinarian's instructions.

Storage Instructions

Store at temperatures between 68° - 77°F.


What is Hydrocortisone Cream 2.5%?

Hydrocortisone Cream 2.5% is used to reduce skin inflammation.

What are the benefits of Hydrocortisone Cream 2.5%?

Helps reduce inflammation. Also used to treat minor skin irritations and rashes such as insect bites, contact dermatitis and itching.

What form(s) does Hydrocortisone Cream 2.5% come in?


How does this medication work?

Hydrocortisone belongs to a class of drugs known as glucocorticoid steroids, meaning they are steroid hormones with a glucose (sugar) molecule attached. Such hormones are produced naturally by the adrenal glands.

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