Interceptor Plus Chew for Dogs, 50.1-100 lbs, (Blue Box)

By Interceptor Plus
Rated 4.6065 out of 5 stars
Prescription Item

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$70.17Chewy Price
$66.66Autoship Price
(Save an extra 5%)

Why Autoship?

  • Save 5% on all future Autoship orders
  • Set your schedule based on your pet's needs
  • No fees, no commitments - skip, change or cancel anytime.
In Stock
FREE delivery
Usually arrives in 3-5 days
We'll collect your pet's prescription information at Checkout.

This item requires prescription approval.

Medications ship separately. Delivery times may vary.

About This Item


  • Interceptor PLUS protects against more types of worms than other formulas
  • Tasty, monthly chewable is flavored with real chicken, making dosing easy
  • Prevents heartworm disease plus treats and controls adult hookworm, roundworm, whipworm and tapeworm infections
  • Covers worms commonly found in dog parks trails, backyards or carried by mosquitoes
  • Delivers 30 days of protection

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Play Video: Learn More About Interceptor Plus From Our Team of Experts
Learn More About Interceptor Plus From Our Team of Experts

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About Interceptor Plus

Upgrade Your Heartworm Protection

Interceptor Plus (milbemycine oxime/praziquantel) combines heartworm disease prevention with the treatment and control of adult hookworm, roundworm, whipworm and tapeworm infections. It’s a once-a-month, chicken-flavored chewable that’s safe for puppies 6 weeks and older, weighing over 2 pounds.

Broad Spectrum Protection

Protect your dog against five different parasites with just one chew. Interceptor Plus prevents heartworm disease and controls hookworm, roundworm, whipworm, and tapeworm threats for a full month to help give you peace of mind on all your adventures. Each box contains stick-on labels for your calendar, making reliable, year-round protection easy to remember with a monthly reminder.

5 Parasites, One Easy Dose

The two powerful active ingredients in Interceptor Plus, milbemycin oxime and praziquantel, when used according to the label, provides safe and effective broad-spectrum protection against five types of dangerous worms. Make parasite protection one and done every month.

Tasty Chicken-Flavored Chew

Interceptor Plus comes as a tasty, chicken-flavored chew, accepted by 96.6% of dogs in a field study, so you won’t have to battle to get your pup to take his medicine. Dogs love it and pet parents appreciate the ease.Simply give Interceptor Plus to your dog by hand or by adding it to a small amount of dog food, and make sure your dog chews up and swallows the complete dose.

Product Guide

Interceptor Plus offers protection for dogs in most sizes and weights. Choose the option best suited for your furry friend.

2 - 8 LBS

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8.1 - 25 LBS

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25.1 - 50 LBS

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50.1 - 100 LBS

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Interceptor Plus prevents heartworm disease and treats and controls adult roundworm, hookworm, whipworm, and tapeworm infections in dogs and puppies 6 weeks or older and 2 pounds or greater.

Important Safety Information

Treatment with fewer than 6 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Interceptor Plus, dogs should be tested for existing heartworm infections. The safety of Interceptor Plus has not been evaluated in dogs used for breeding or in lactating females. The following adverse reactions have been reported in dogs after administration of milbemycin oxime or praziquantel: vomiting, diarrhea, decreased activity, incoordination, weight loss, convulsions, weakness, and salivation.
See Interceptor Plus product label for complete safety information.

About Interceptor Plus

Interceptor Plus was made to protect canine companions from five common parasitic health threats. Just one dose every month prevents heartworm disease and controls hookworms, roundworms, whipworms, and tapeworms in dogs. Dosing is easy with the chicken-flavored chews, and protection can be achieved year-round with monthly use. Give your dog Interceptor Plus to protect your best friend from these dangerous parasites. Interceptor is a trademark of Elanco or its affiliates. PM-US-20-1050
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ReviewsWrite a Review

Rated 4.6065 out of 5 stars
615 Ratings
Would recommend to a friend

565 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 1 out of 5 stars
By Emily on Oct 30, 2023

Did not work

My dogs have been on Interceptor Plus for almost two years. However, just a few days ago, one of my dogs tested positive for whipworms. I’m religious about giving my dogs this medication on the 20th of every month… I have a reminder set in my phone so I don’t forget. Since this medication is a treatment and preventative for several different types of worms, including whipworms, and I’ve been consistent with timely and accurate dosing, the meds were not expired, and my dogs did not get sick afterwards… my vet was at a loss as to how one of my dogs still got infected with whipworm. He suggested I contact Interceptor directly and see if I can get anywhere that way.

Rated 1 out of 5 stars
By Mary on Nov 17, 2023

Med subscriptions

Wasn’t made clear about meds not considered for e cash cards. Also that to redeem the $30 card I had to spend an additional $100. A definite bait and switch. No more business with you. So long to giving you my business of $69 every month for dog food. I returned the item you are asking about.

Rated 5 out of 5 stars
By Victoria on Nov 30, 2023

Works great!

My two dogs both take this and have never had worms of any kind. It keeps them protected from a variety of parasites and I highly recommend this item. Always a negative fecal sample for any kind of disease and always negative for heartworm.

Rated 5 out of 5 stars
By Steven on Oct 26, 2023

Hassle Free Heart Worm Meds

We ordered our dogs' heart worm pills through Chewy. The process included entering the information for our two dogs and our veterinarian's contact info. Chewy got approval from the vet and we received the meds in about a week total. Definitely a lot easier than taking the dogs in for a visit to renew their heart worm prescription.

Rated 5 out of 5 stars
By GreytMom on Nov 8, 2023

Works well

I have retired racing greyhounds. They usually come in with hookworms. I haven't had any problems with hookworms since putting them on the Interceptor. One of my greys doesn't like the taste, so I just cut it into pieces and put it in his food.

Rated 5 out of 5 stars
By Georgia on Nov 9, 2023

Great service!

I realized almost too late that our Lab was going to run out of food within 2 days. I quickly changed the date (late in the afternoon) The order was immediately prepared and shipped! Thanks soooo much for your customer service.

Rated 5 out of 5 stars
By Jill on Nov 10, 2023

My dogs love these

Recommended by our vet. We give these to our dogs monthly. There's a lot of packaging which can be tough to open but once inside, the meaty flavored treats are eagerly eaten by each dog.

Rated 5 out of 5 stars
By Marilyn on Nov 2, 2023

Good Heartworm Prevention

Works well and has the added benefit of preventing a variety of worms. Our dog is at doggie daycare once a week, so we appreciate the extra protection now that she's around groups of dogs each week.

Rated 5 out of 5 stars
By Bonnie on Oct 20, 2023

Always Great Communication

I was not sure if my Vet approved the requests, and Chewy did a great job communicating with me, through the entire process. I greatly appreciate all the time and effort that Chewy invested in my order.

Rated 5 out of 5 stars
By sheryl on Sep 24, 2023

last order

I was having issues with getting this order due to my vet not understanding that the order was for two pets and it took 3 calls to my vet and 2 to chewy. Your employees on the phone were soooo helpful in helping me fix this issue. Thank you so much for being so patient with us.