K9 ADVANTIX II Flea & Tick Spot Treatment for Dogs, 11-20 lbs, 6 Doses (6-mos. supply) - Chewy.com

K9 Advantix II Flea & Tick Spot Treatment for Dogs, 11-20 lbs

By K9 Advantix II
Rated 4.1161 out of 5 stars

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$69.98Chewy Price
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About This Item


  • Broad-spectrum, veterinarian-recommended treatment repels and kills fleas, ticks and mosquitoes on dogs 7 weeks or older and weighing 11-20 pounds.
  • Begins working within 12 hours and kills pests on contact.
  • Kills all life stages of fleas to prevent re-infestation; also kills lice and even repels biting flies.
  • Waterproof formula continues working for up to four weeks, even after bathing or swimming.
  • Convenient, monthly topical application contains imidacloprid, permethrin and pyriproxyfen; available in packs of 2, 4 or 6 treatments.

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Play Video: Learn More About K9 Advantix II From Our Team of Experts
Learn More About K9 Advantix II From Our Team of Experts

Important Information

Fleas rise to the top of your pet's coat as they die, so consider it a triumph if you start seeing more fleas at first, after treating your pet. If you’re still seeing fleas after application, it may be because your pet has picked up new fleas from the environment, which may include other pets, surfaces and outdoor areas. It may take up to 30 days to break the entire flea life cycle. Additionally, you should also treat sources of new fleas (i.e., carpet, yard, etc.) to ensure complete flea control.

About K9 Advantix II

Experience the Advantages of K9 Advantix II

Veterinarian-recommended K9 Advantix II kills fleas, ticks, mosquitoes and lice, and repels biting flies. Now you can help your dog fight these pesky pests through contact—no biting required. Convenient and easy to use, K9 Advantix II is for dogs and puppies 7 weeks of age or older. So help your pal get the effective protection he needs with all of the advantages of K9 Advantix II.

Why are Biting Bugs a Big Deal?

K9 Advantix II spreads over the skin and hair to kill and repel them through contact, meaning they do not have to bite to die. And if a flea, tick or mosquito is repelled, it cannot bite and transmit disease.

Why Choose K9 Advantix II?

Fleas, ticks and mosquitoes can negatively affect your pet's health. It's important to use an effective product that kills pests which can spread disease. Fleas can cause flea allergy dermatitis, an allergic reaction that can lead to constant scratching, severe itching and even hair loss. Ticks can transmit deadly diseases, such as Lyme disease and Rocky Mountain spotted fever. And mosquitoes can potentially carry dangerous diseases, too, including heartworm. K9 Advantix II should not be used in place of a heartworm disease prevention product.

Is K9 Advantix II the Right Choice for Your Dog?

Whether your dog is a winter snow hound or a summer backyard explorer, an sunseeker or an outdoor enthusiast, choose K9 Advantix II to help keep fleas, ticks and mosquitoes from interrupting his favorite activities year-round. If you want to return the love to your dog, take care of him with flea prevention that works to kill the fleas you see and the ones you don't.

K9 Advantix II Has a Treatment for Dogs Large and Small


4-10 pounds


11-20 pounds


21-55 pounds


55 pounds and over

Do not use K9 Advantix II on cats.

About K9 Advantix II

K9 Advantix II is manufactured by Bayer, a leading name in the healthcare industry for over 150 years. K9 Advantix II is a monthly flea, tick and mosquito treatment for your dog that kills through contact—no biting required. It starts working to kill fleas within 12 hours of application and is veterinarian recommended, so you can feel confident knowing that your pet is getting effective protection.
Shop Bayer

Questions & Answers

23 Customer Questions

I see a lot of reviews for fleas but I have a trouble with ticks. How good is this at preventing and killing ticks?
Answer by ChewyMar 13, 2018
This product repels and kills ticks including Deer ticks, American dog ticks, Brown dog ticks, and Lone Star ticks for up to 4 weeks.

What's the expiration date? I can't find it on the box?
Answer by ChewyMar 19, 2018
This product does not have an expiration date. It will be safe to use as long as you store unused containers in their original packaging and at room temperature.

Can this product be used at the same time as heartworn medications
Answer by ChewyOct 23, 2017
We'd recommend speaking with your veternarian before applying this treatment while using heartworm medication.

does it kill the eggs and mosquitos
Answer by ChewyMar 25, 2018
The Treatment kill fleas of all stages and also repels and kills mosquitoes.

ReviewsWrite a Review

Rated 4.1161 out of 5 stars
930 Reviews
Would recommend to a friend

930 Customer Reviews

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Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 4 out of 5 stars
By lahpetchonka5199 on Mar 13, 2023

Buttons and Papi

They are allergic to wearing the plastic collars;they both scratch continuously until hair falls out, so I get them fle and tick spot, which I usually get frontline but this is suppose to kill so much more. I only used one application, but the tubes are so small, I swear nothing came out of the one I put on Buttons and she was still scratching. Papi's tube wasn't full either, I hope this isn't the rest of them!

Rated 4 out of 5 stars
By Andy on Feb 22, 2023

Good product

I give my dogs Advantix II and Heartguard the first of every month. They work well. The only thing I didn't like was having two shipments because one required vet approval. Just hold one until the other is ready and mail them both at the same time. Otherwise I have to watch for 2 packages and fend off porch pirates until I can get home.

Rated 1 out of 5 stars
By KellyJo on Dec 23, 2022

Bad reaction

We have a 14 lb mini poodle / Jack Russell mix. We've always got the Revolution, or the Selerid flea tick heartworm but she had a shot for heartworm so my vet said to order any flea/tick topical for her. The treatment the vet had was around $133.00. I saw the price of the K9 Advantix and ordered it. For some reason they didn't have to send order to get the vet to approve it. I applied the treatment last week; followed directions on the box. She had a horrible reaction later that night. Vomitted her dinner and was going nuts and could tell the 3 places where I put the treatments were irritating her skin. Since then she has not been able to keep any food down. Every meal she has vomitted and she still reaching toward her backside where I placed treatment. I called the vet and then called the # on back of box of the manufacturer. They suggested we wash the area. We have done that twice and this hasn't helped. Whatever is in the K9 Advantix is way to potent for her and just wanted to warn others about that. We are going to reach out to her vet again today since she hasn't eaten in 4 days. Lesson learned; will stick w/ what I know and not try to save a dollar.

Rated 5 out of 5 stars
By Mimi on Feb 15, 2023

BEST service ever!!!

I have been buying from Chewy for a long time (and always recommend it to all my friends) and wouldn't buy from anyone else. Always the BEST service and has the best selection of anything you might need!!

Rated 5 out of 5 stars
By DiJeff on Nov 23, 2022

Good stuff!!

I have used this flea treatment for years and it has always worked for us. I have noticed no adverse reaction and do not use flea shampoo or other flea products. We live on 5 acres and our dogs come in/out as they please. I like that you don't need any type of RX from the vet. Chewy has good incentives to purchase from them throughout the year!

Rated 1 out of 5 stars
By ewally on Feb 17, 2023


This caused angry irritation at the application site with days of intense itching at the site. I will not use on my dog again.

Rated 1 out of 5 stars
By JohnyG on Nov 18, 2022

Would give it 0 stars or less.

Compared to the small bit of searching our dog did from the few fleas we found. ADVANTIX 2 tortured him. His skin turned raw and so far foe over 24 hours he is suffering. The vet said to wash it off of him and give him Benadryl which has only given him a little relief and they said if it continues tomorrow to bring him in for a huge vet bill I'm sure Do not make the same mistake!! Andvatix 2 has been a nightmare.

Rated 1 out of 5 stars
By Rick on Nov 15, 2022

doesn’t seem the same , and and 1 empty vile

used this a long time ago & it worked great recently bought again for my 3 shih tzus for a small flea problem, not even an infestation & it doesn’t seem too work, also i opened the package & applied it on 2 of my dogs then got to the third & opened the bottle & there was literally nothing inside no liquid, probably best to get vet flea perscription

Rated 5 out of 5 stars
By birdgog on Mar 12, 2023

Tic preventive

right price and prompt delivery I highly recommend Chewy for your pet supply.

Rated 4 out of 5 stars
By calv16 on Feb 25, 2023

so far so good

it works great the first 2 wks but by the 3rd weeks it starts to stop working