Lantus SoloStar Insulin Glargine Injection U-100, 3 mL, slide 1 of 1

Lantus SoloStar Insulin Glargine Injection U-100, 1-Prefilled 3-mL Pen

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Medications ship separately. Delivery times may vary. Details

This item is specially packaged to remain refrigerated during transit.

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Insulin glargine is an injectable drug used to treat diabetes mellitus, and works by lowering blood sugar. While the FDA has approved insulin only for use in humans, veterinarians are allowed to prescribe it to animals such as dogs, cats, horses, cattle, ferrets and guinea pigs in certain situations. Insulin glargine should be refrigerated until it has been opened, and then it must be kept at room temperature. It should never be stored in the freezer and should be protected from direct heat and light. Talk to your veterinarian about the right dosage for your pet.

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Insulin preparations are used for the adjunctive treatment of diabetic ketoacidosis (DKA), uncomplicated diabetes mellitus, and as adjunctive therapy in treating hyperkalemia.

Possible Side Effects

Adverse reactions commonly associated with Lantus include hypoglycemia, allergic reactions, injection site reactions, lipodystrophy, pruritus, rash, edema and weight gain.

Drug & Food Interactions

Drugs that affect glucose metabolism: Adjustment of insulin dosage may be needed; closely monitor of blood glucose. Antiadrenergic Drugs (e.g., beta-blockers, clonidine, guanethidine, and reserpine): Signs and symptoms of hypoglycemia may be reduced or absent.


Hyperglycemia or hypoglycemia with changes in insulin regimen: Carry out under close medical supervision. Hypoglycemia: May be life-threatening. Increase frequency of glucose monitoring with changes to: insulin dosage, coadministered glucose lowering medications, meal pattern, physical activity; and in patients with renal or hepatic impairment and hypoglycemia unawareness. Medication Errors: Accidental mix-ups between insulin products can occur. Check insulin labels before injection. Hypersensitivity reactions: Severe, life-threatening, generalized allergy, including anaphylaxis, can occur. Discontinue Lantus. Monitor and treat if indicated. Hypokalemia: May be life-threatening. Monitor potassium levels in patients at risk of hypokalemia and treat if indicated. Fluid retention and heart failure with concomitant use of thiazolidinediones (TZDs): Observe for signs and symptoms of heart failure; consider dosage reduction or discontinuation of TZD if heart failure occurs.

Note: This item does not come with needles. Needles sold separately.

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  1. Prescribing Information

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  • Item Number
  • Common Brand Name(s)
  • For Use With
    Dogs & Cats
  • Generic Name
    Insulin glargine
  • Administration Form
  • Product Form
  • Health Condition
  • Drug Type

Lantus consists of insulin glargine dissolved in a clear aqueous fluid. Each milliliter of Lantus (insulin glargine injection) contains 100 units (3.6378 mg) insulin glargine. The 3 mL prefilled pen presentation contains the following inactive ingredients per mL: 30 mcg zinc, 2.7 mg m-cresol, 20 mg glycerol 85%, and water for injection. The pH is adjusted by addition of aqueous solutions of hydrochloric acid and sodium hydroxide. Lantus has a pH of approximately 4.

Recommended Dosage

Consult with your veterinarian on recommended dosage

Storage Instructions

Refrigerate unopened Lantus Insulin 3mL. Opened Lantus Insulin 3mL must be stored at room temperature only. Lantus should not be stored in the freezer and should not be allowed to freeze. Discard Lantus if it has been frozen. Protect Lantus from direct heat and light. The shelf life of Lantus is 28 days after first use.


How is this medication useful?

Insulin is used to lower blood sugar in animals with diabetes mellitus (sugar diabetes). Insulin comes in many forms that vary in their duration of effect, potency, and concentration. Insulin is an ongoing or supportive treatment for animals with diabetes.

How long until I will know if this medication is working, and how long will the effects of this medication last?

This medication should start having effects within 1 to 2 hours; however, you will not see the effects of this medication outwardly. Your veterinarian will need to run further tests to determine if the medication is working appropriately. The effects of this medication are short-lived, meaning they will stop working within 24 hours.

What other information is important for this medication?

  • If you take your animal out of the house (including on walks), never leave home without a sugar source (eg, packets of honey, liquid glucose packets [available at pharmacies], small plastic bottles of corn syrup or, in a pinch, little packets of table sugar [do not give sugar substitutes]) in case your animal's blood sugar drops.

  • Purchase an identification tag for your animal to wear to indicate it has diabetes; be sure to include your veterinarian's name and phone number.

  • Do not change or switch your animal's diet or exercise routine without first checking with your veterinarian.

Rating: 5.0 of 5 stars 3 Reviews 3 Reviews 5 out of 5 Stars

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  • 5 out of 5 stars

    Great so far

    By bluedovepdx on Nov 4, 2021

    My girl Ellie (12 yrs + 9 months old exactly as of today) is new to diabetes treatment. Vet doc recommended/prescribed the Lantus pen. We started yesterday. Too soon to know how effective the medicine will be but the pen is excellent. Very easy to use. I was able to buy a single pen from a non-Chewy source. It was all about the cost. I wish Chewy would make available single pen purchases. For my intial purchase of needles I chose BD Nano Ultra Fine 32G 4 mm pen needles. Easy to attach to the pen. Seems to cause no pain/discomfort for my Ellie. Very happy about that. It's a twice a day thing.

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  • 5 out of 5 stars

    Cat responds well to this insulin

    By Bev3 on Feb 11, 2020

    Very pleased with how my cat has responded to this 12 hour insulin. She is also on a small dose twice a day and it is more affordable for us to use this SoloStar pen like a vial drawing out her dose with a syringe. Kept in the refrigerator it will last several months. Be sure to use the correct syringe size U-100 with this type of insulin.

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  • 5 out of 5 stars

    Nice to have a smaller volume of insulin

    By MCSS on Feb 9, 2020

    Our cat only needs a small dose and buying a vial most of it would go to waste. The pen works great for smaller dosing. We do not use pen needles, we use a standard needle for dosing per our vet.

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