NexGard Chew for Dogs, 4-10 lbs, (Orange Box)

By NexGard
Rated 4.6057 out of 5 stars
Prescription Item

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$266.78Chewy Price
$285.98Chewy Price
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$19.20 (7%)
$253.44Autoship Price
(Save an extra 5%)

Why Autoship?

  • Save 5% on all future Autoship orders
  • Set your schedule based on your pet's needs
  • No fees, no commitments - skip, change or cancel anytime.
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Usually arrives in 3-5 days
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This item requires prescription approval.

Medications ship separately. Delivery times may vary.

About This Item


NexGard Chews for Dogs, 4-10 lbs. are vet-recommended and FDA-approved to kill adult fleas fast before they have a chance to lay eggs. This product is also FDA-approved to help prevent Lyme infections as a direct result of killing black-legged ticks. Each fast-acting chew provides safe and effective protection, killing fleas and ticks for a full month. And the chews are easy to give because dogs love the delicious beef flavor—you may even give them to your dog with or without food! Each NexGard bite-sized monthly dose is gentle enough to give to puppies and dogs as young as 8 weeks, weighing as little as 4 pounds.

Proudly sourced directly from the manufacturer or their approved distributor. Guaranteed genuine and backed by the manufacturer.

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Play Video: Learn More About NexGard From Our Team of Experts
Learn More About NexGard From Our Team of Experts

Frequently Bought Together

NexGard Chew for Dogs, 10.1-24 lbs, (Blue Box), 6 Chews (6-mos. supply)
Rated 4.6601 out of 5 stars
$136.49Chewy Price
Total Price: $451.86

About NexGard Chewables

Powerful Protection Image

NexGard (afoxolaner) is the chew that dogs love.* It kills fleas and ticks all month long and even prevents flea infestations. So, not only is NexGard delicious, but it also keeps your dog protected from fleas and ticks!

The Chew Vets Choose*

NexGard is the #1 vet-recommended flea and tick protection, and the chew vets choose to protect their own dogs.*

Trusted Over 270 Million Times*

See why NexGard is the #1 Choice of Vets.*

#1 Dog-Preferred

NexGard’s delicious beef flavor makes it the #1 dog-preferred chew over other chews that kill fleas and ticks.*

Legacy of Trust

NexGard is the #1 choice of vets and has been prescribed over 270 million times.*

Safe for Puppies

NexGard is safe for dogs and puppies who are as young as 8 weeks and who weigh just 4 pounds.

Kills Fleas and Ticks

NexGard is FDA-approved to prevent the infections that cause Lyme disease by killing black-legged ticks.

Enjoyable Every Month

Every delicious NexGard chew makes it easy to protect your dog for a full month.

For Dogs, Big and Small

Comes in four sizes: 4-10 lbs., 10.1-24 lbs., 24.1-60 lbs. and 60.1-121 lbs.

Protection for Every Season

Your dog can get fleas any time of the year throughout much of the United States. And some ticks, including those that transmit Lyme disease, can be active in temperatures that are just above freezing. Just 1 monthly NexGard chew will kill fleas and ticks and protect your dog, no matter the season.

Never Miss a Dose with Autoship

Sign up for Autoship today and save on the #1 vet-recommended chew.* Not only will you get a discount on NexGard, but you can rest easy knowing that the #1 dog-preferred flea and tick protection will be delivered to your door when you need it.*

NexGard’s Mission

NexGard is committed to enhancing pet well-being and to supporting the animal health community. When you purchase NexGard, you are not only protecting your dog with the #1 vet-recommended flea and tick protection*, but you are also supporting the commitment to donate over 250,000 doses of NexGard to animal shelters each year.*

About NexGard

NexGard is the #1 vet-recommended flea and tick protection.* 1 monthly chew will keep your dog protected from fleas and ticks, plus dogs love the delicious beef flavor, making it easy to give with or without food.* NexGard is also FDA-approved to prevent the infections that cause Lyme disease by killing black-legged ticks. It is safe for puppies who are 8 weeks of age and who weigh 4 pounds or more. Plus, it’s available in four sizes, so every dog can get the protection they need.

Shop NexGard

*Data on file at Boehringer Ingelheim.

ReviewsWrite a Review

Rated 4.6057 out of 5 stars
317 Ratings
Would recommend to a friend

289 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 5 out of 5 stars
By Suellen on Nov 21, 2023

Best flea pill I have used

I have a small female Pomeranian that is prone to having seizures. This pill is the safest as far as I know. It works great on Fleas, Ticks and Mosquitoes and she has had no side effects from it.

Rated 1 out of 5 stars
By holli on Nov 4, 2023

I canceled this autoship

It was shipped erroneously before and I contacted chewy to cancel the autoship as I have a ton of this medicine in hand. Looos like the cancellation didn’t work and now I have more and none of the hart guard.

Rated 5 out of 5 stars
By kyro on Aug 11, 2023

I live by this product !

I don’t write to many reviews, but today I just decided I’d share since my autoship just shipped :) my little 4lb teacup Yorkie so easily gets fleas ! and he used to never be so prone to them but where we lived I guess didn’t spray the grass even though they said they did. 2 years ago he got them and I’d notice he’d itch a lot I would just think it was dry skin but I bought a flea comb and man once I saw a little tiny brown bug crawling on the comb I almost passed out !! I gave him a bath probably 6 times that night ! with dawn & his shampoo . It helped for like a night .. and they were back ! I did so much research & I’m very picky with what I give him being that he’s so small, but this stuff works great ! I highly recommend I DONT PLAY about bugs at all , MY BIGGEST FEAR ! so this definitely makes me feel comfortable with cuddling up with him again because those things BITE humans too . they don’t care to much about you but if you’re hugging and cuddling your dog they will definitely eventually begin to bite you too . So just be careful and please use this stuff . I’ve been on autoship for 2 years now . In the winter seasons I put it on pause because it’s not necessary for him & he does just fine .

Rated 4 out of 5 stars
By Gary on Nov 26, 2023

Very expensive, particularly for 2 dogs but delivery occurs without any issues.

I guess NexGuard and Interceptor Plus works because we never find any ticks or fleas on them and no signs of heartworm either.

Rated 5 out of 5 stars
By Kathy on Nov 5, 2023


I was getting at my vet and it was costing me about $15 more. It was easy ordering it through Chewy they contacted my vet and shipped it to me.

Rated 5 out of 5 stars
By Sherri on Nov 24, 2023

We LOVE Chewey!!

The sales people on the phone are ALWAYS so nice, friendly and helpful. I love spending money with Chewey!!

Rated 5 out of 5 stars
By Cheryl on Nov 1, 2023

great product

we've been giving these to our pets for years and never had a problem with side effects. Highly recommend this product.

Rated 5 out of 5 stars
By Cindy on Jul 30, 2023

product was good

I was not pleased with the way I got it. I tried to add it and Bravecto to my Auto ship. I ended up with 2 orders, 3 days apart. Dog food and nexguard in one and dog food again 3 days later. I ended up not getting the Brovecto because the wrong weight was sent to my vet. Not sure I will keep up with autoship, this is my second time of frustration trying to add to an order.

Rated 5 out of 5 stars
By Mary on Nov 4, 2023

Nexgard Chews

I have used this product for my dog Bella for 5 years. She is doing very well so I recommend thisi product.

Rated 1 out of 5 stars
By MissTinkerBell on Aug 19, 2023

Doesn't work

My Pomchi weighs 4 pounds & I gave her a chew for flea & tick prevention that is supposed to last one month. She still got flea. I also cleaned all her bedding & gave her flea baths. Nexguard did not work.