What is Dasuquin® for Dogs?
Dasuquin from Nutramax Laboratories Veterinary Sciences, Inc. is a joint health supplement for dogs that goes beyond standard glucosamine supplements. It contains NMX1000®* avocado/soybean unsaponifiables (ASU), green tea extract (EGCG), FCHG49®* glucosamine hydrochloride, and TRH122®* low molecular weight chondroitin sulfate in a chewable tablet and soft chew. It is a comprehensive joint support supplement.
What role do the glucosamine hydrochloride and low molecular weight chondroitin sulfate play?
The combination of the trademarked FCHG49 glucosamine hydrochloride and TRH122 low molecular weight chondroitin sulfate supports cartilage matrix production and helps block enzymes in joints that break down cartilage. These ingredients together have been shown in published studies to protect joint cartilage better than either ingredient alone. A greater than additive effect, known as a “synergistic” effect, on cartilage cells was seen using this glucosamine and low molecular weight chondroitin sulfate together.
What is ASU, and how does it work?
ASU stands for avocado/soybean unsaponifiables, an ingredient concentrated directly from avocados and soybeans that is used for joint health. ASU has been shown to improve joint function and comfort levels. Studies using cartilage cells have shown that ASU lowers the expression or production of several compounds involved in the process of cartilage breakdown in joints. ASU complements the positive effects of the other active ingredients in Dasuquin. The glucosamine in Dasuquin is synergistic with low molecular weight chondroitin sulfate and has been shown in cartilage cell studies to be synergistic with ASU. Of note NMX1000 avocado/soybean unsaponifiables, FCHG49 glucosamine hydrochloride and TRH122 low molecular weight chondroitin sulfate together were shown in cell studies to be better than the combination of glucosamine and chondroitin sulfate alone at inhibiting expression of several agents involved in the breakdown of cartilage. The highly absorbable green tea extract (EGCG) is rich in antioxidants, which have a positive effect on cartilage as well as on overall body defenses.
How do I know if my dog needs Dasuquin?
It may be a good time to ask your veterinarian about Dasuquin if you notice that your dog slows down during walks, does not get up easily, or is reluctant to climb stairs or jump into the car. Your veterinarian will examine your dog to determine if he/she could benefit from Dasuquin. If your veterinarian has already recommended Dasuquin, the sooner it is started the more opportunity your pet will have to respond. Your veterinarian may also suggest using Dasuquin as a protective measure. This can be important for maintaining an active life for many dogs, especially large breeds and working dogs of all sizes. Dasuquin may also be used to help support cartilage following joint surgery.
What should I be looking for when giving my dog Dasuquin?
Observe your dog closely, and notice whether your dog seems more comfortable doing those activities he seemed reluctant doing or had some trouble doing previously. Changes in your dog’s comfort level may occur gradually. Allow time for your dog to respond. It may take 4 - 6 weeks, though some dogs may respond sooner.
What else can I do for my dog?
Your veterinarian may recommend exercise, which is important for optimal joint function as well as weight control and the overall health of your pet. Joint movement is needed to circulate fluid around the cartilage as well as to bring nutrients and to remove waste products. It has been shown that when joints are immobilized, cartilage structures deteriorate at a rapid rate. You should ask your veterinarian, but in most cases, moderate exercise is recommended. Walking on sand or another soft surface or even swimming will help circulate needed nutrients and reduce excessive stress to the cartilage. It is important not to push your pet but to exercise at a comfortable pace.
Are there any safety concerns in dogs with Dasuquin use?
While sensitivity to avocados has been reported in a few dogs, taking Dasuquin tablets is not the same as eating whole avocados. The ASU in Dasuquin has been evaluated in a safety study in dogs, and no adverse effects were noted from administration. There are no known contraindications or known interactions between Dasuquin and any drug or supplement.