Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Medium Dogs

By Nutramax
Rated 4.6227 out of 5 stars

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$43.99Chewy Price
$41.79Autoship Price
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Why Autoship?

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  • Set your schedule based on your pet's needs
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About This Item


  • Denamarin contains s-adenosylmethionine (SAMe) to help increase gluthione levels to support your dog’s liver detoxification capabilities.
  • Silybin found in Denamarin has shown better absorption in dogs than the milk thistle extract found in many other products.
  • Supporting your dog’s liver health promotes the liver’s ability to remove toxins, store energy, aid digestion and support the immune system.
  • Nutramax Laboratories Veterinary Science has made supplements to support joint health, digestive health and overall wellness for over 30 years.
  • Veterinarian formulated with high-quality ingredients to ensure supplement safety.

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Nutritional Information

Feeding Instructions


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Top IngredientsActive Ingredients: S-Adenosylmethionine, Silybin A+B.S-Adenosylmethionine.Active Ingredients: S-Adenosylmethionine, Silybin A+B.Active Ingredients: S-Adenosylmethionine, Silybin A+B.S-Adenosylmethionine 225 mg, Silybin-phosphatidylcholine complex (SPC)* 82 mg, *Providing 24 mg of Silybin A+B....
Breed SizeSmall Breeds, Medium BreedsSmall Breeds, Medium BreedsExtra Small Breeds, Small Breeds, Medium Breeds...Extra Small Breeds, Small BreedsMedium Breeds
Health FeatureLiver CareLiver CareLiver CareLiver CareLiver Care, Vitamins & Minerals
LifestageAdult, SeniorAdult, SeniorAdult, SeniorAdult, SeniorAll Lifestages
Food FormSupplementSupplementSupplementSupplementSupplement

Questions & Answers

17 Customer Questions

When do you think the Denamarin tablets in?

Which is easier for the dogs to take, the regular or chewable?
Answer by ChewyJun 20, 2019
Ease of administration between these tablets and the chews will vary from pet to pet. This medication should be administered on an empty stomach at least 1 hour before eating. If you must mask with food it is recommended to use no more than a tablespoon.

How long can my dog stay on denamarin?
Answer by ChewyMay 09, 2018
This depends on the current condition of your dog. These tablets are safe for long term use. We recommend consulting a veterinarian for accurate feeding regimes based on your dog's health.

Are there any side effects from taking Denarmarin
Answer by ChewyFeb 04, 2020
The active ingredients in Denamarin have been shown to be well-tolerated by both dogs and cats with a wide margin of safety. We advised consulting with your veterinarian before administering.

ReviewsWrite a Review

Rated 4.6227 out of 5 stars
432 Ratings
Would recommend to a friend

432 Customer Reviews

Rated 5 out of 5 stars
By Lucy on Sep 3, 2023

Beware of melting in summer heat

This product in all of its forms has been a life saver for several of my dogs over the years. Somehow my product was changed from the blister pack with blue tablets to these tan coated bottle of tablets. This product has several storage reuirements and we've had some record breaking heat waves so i checked the temperature in the box when it arrived and it was over 100F degrees and the tablets were melted inside. I also noticed my dog was not feeling well. Anyway, the blister pack tablets seem to be better in the heat. I'm grateful for this product and of course, we all know Chewy is going to make everything okay again. Just a note: please be aware of heat effects on medication shipments.

Rated 3 out of 5 stars
By JR on Aug 27, 2023


I’ve been giving this to my dog since well before I can remember. Recently the shape was changed from capsule to tablet; the tablets are not easy to camouflage in anything because they are so large. In addition, I have experienced, several times, a shortage in the product and was in a panic; I contacted the company. Thank God, this is not a prescription, as then it would be required to take daily (for which I wouldn’t have enough of and my dogs would wind up going into withdrawal with side effects).

Rated 5 out of 5 stars
By Lindy on Jul 24, 2023

Noticeable improvement

My 14 (almost 15) year old yorkie mix had blood work down that showed extremely high liver enzymes, ALK-P specifically was over 2000. Less than 1 month on this supplement he was down to under 800. He is on this daily and we will continue to monitor but There is a very noticeable improvement in his alertness and energy level.

Rated 5 out of 5 stars
By Kathy on Jul 5, 2023

Outstanding Customer Service

Thank you for the chance to tell you about your great customer service the last 5-6 weeks: A sick dog is heartbreaking and when it sadly ended with my Twiggy crossing over. Chewy was so so very kind helping with stopping the auto ship of this medication. Removed her profile and messaged with a Chewy employee. Received a lovely flower arrangement the next day. Continued customer forever. Thank you Chewy....

Rated 3 out of 5 stars
By Sara on Aug 17, 2023

Can’t give it 1 star nor 5 star

I can’t really truly rate this being that my dog passed away a few days after she started this liver supplement. I guess I’ll never know how helpful this liver support would have been for her.

Rated 5 out of 5 stars
By Debbie on Jul 30, 2023

Great Product

Our 10 year old long haired chihuahua was prescribed this due to highly elevated liver numbers through bloodwork. After just one month the numbers started coming down. He will remain on it the rest of his life. He is feeling so much better!

Rated 5 out of 5 stars
By Lizzy on Aug 21, 2023

Does not seem to make a difference

Does not seem to make a difference but our new vet wants to keep Gibby on it until she has been on her new medication a while longer. Then she will be weaned off of it. Yay!

Rated 5 out of 5 stars
By Donna on Sep 13, 2023

My Molly

Molly has an enlarged liver and needs liver supplements. She’s been taking them for more than a month and seems to be feeling better.

Rated 5 out of 5 stars
By hugomama on Jul 12, 2023

Worked for my dog

My dog had some digestive issues and blood test showed his liver enzymes we slightly elevated. My vet recommended for my dog to take this and it has helped alot. Liver levels are back to normal and we havent had digestive issues in while. It's pricey but cheaper than a vet bill!

Rated 5 out of 5 stars
By Shannon on Sep 15, 2023


Chewy took care of confirmation with my vet, I had to do nothing. They communicated every step. The shipment came fast.