NUTRAMAX Denamarin Tablets with S-Adenosylmethionine SAMe & Silybin Liver Health Supplement for Small Dogs & Cats, 30 count -

Nutramax Denamarin Tablets with S-Adenosylmethionine (SAMe) & Silybin Liver Health Supplement for Small Dogs & Cats

By Nutramax
Rated 4.4702 out of 5 stars
Breed Size

$32.99Chewy Price
$31.34Autoship Price
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About This Item


  • Denamin contains s-adenosylmethionine (SAMe) to help increase gluthione levels to support your dog and cat’s liver detoxification capabilities.
  • Silybin found in Denamarin has shown better absorption in dogs and cats than the milk thistle extract found in many other products.
  • Supporting your dog and cat’s liver health promotes the liver’s ability to remove toxins, store energy, aid digestion and support the immune system.
  • Nutramax Laboratories Veterinary Science has made supplements to support joint health, digestive health and overall wellness for over 30 years.
  • Veterinarian formulated with high-quality ingredients to ensure supplement safety.

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Nutritional Information

Feeding Instructions


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Questions & Answers

29 Customer Questions

Is the medication inside the tablet absorbed even if the outer gel rubbery tablet is still intact after in the stomach for a few hours?
Answer by SpencerSep 14, 2021
I am having the same issue with my small dog. He throws it up intact. I now put a small nick in the gel coating to make sure it dissolves.

When will have this medicine ?
Answer by MillyJun 07, 2022
You can get the one for cats and dogs 12#. It has directions for over 12#

Is it OK for dog to take CBD while taking Denamarin?
Answer by PatriceMar 02, 2023
Yes per my vet

Answer by ChewyJul 09, 2018
Overnight fast meaning not to feed your dog the night prior to treatment.

ReviewsWrite a Review

Rated 4.4702 out of 5 stars
336 Reviews
Would recommend to a friend

336 Customer Reviews

Show reviews that describe

Rated 5 out of 5 stars
By nori on Feb 13, 2023

Cat takes it.

I pill my cat orally first thing in the morning on an empty stomach and then give her the B12 by the same manufacturer as a treat. She will usually then go drink water from her fountain. This system works well for me. I then wait 30 minutes to 1hr and then give her food with one pack of immuquin, also made by this brand. Backstory: My cat's liver enzymes came back elevated at her recent bloodwork so I did my research and wanted to add supplements to help her before going for an ultrasound. I'm hoping to see good results because we are making sure she is taking these religiously. I will update the review after her bloodwork in the future.

Rated 1 out of 5 stars
By Patrice on Feb 27, 2023

The dye runs off on your fingers

I bought this for my ailing dog. (bad liver) The dark blue dye covered my fingers when I was giving it to her. Then it was on her tongue and fur on her lower mouth. I ended up only giving her 2 pills because she got very loose stool just after two pills. I'm not sure if this caused her problem but it was the only new med/food given/introduced to her and her stool became normal a day later.

Rated 4 out of 5 stars
By AKPO on Jan 3, 2023

Blue Coating

We were happy to find this available on Chewy after our vet stopped offering it. The replacement from our vet was making our dog sick so we went back to the old option, Denamarin. My only complaint is the blue coating which comes off on everything. It takes a few times to get my dog to swallow her pill and in that time her white fur, my hands, and the pill shooter all become covered in bright blue residue. We didn't have this problem when we were able to get it directly from the vet so I'm not sure what the change has been.

Rated 1 out of 5 stars
By B1234 on Jan 30, 2023

Made my cat throw up

I was giving this my cat for a few days, as the vet recommended a liver supplement for him. He kept throwing up everyday. I discontinued and he has not thrown up at all. Something in this pill makes him very ill. Contacted Chewy and they refunded my money. Great customer service.

Rated 5 out of 5 stars
By fifi on Jan 28, 2023

size of boxes used

The boxes seem overly large for the contents. Since freight isn't charged, it's not an expense to me, but it is a wsste of boxes. perishable liquids are in boxes not labeled "perishable, do not freeze".

Rated 5 out of 5 stars
By Case on Feb 19, 2023

Denamarin liver supplement

My elderly dog has been on Denamarin for about 3 years. He has elevated liver enzymes and the Denamarin seems to be keeping his lever disease stable.

Rated 5 out of 5 stars
By Carol on Feb 25, 2023

Good Value

This liver supportive supplement is recommended by my vet. Chewy's cost is considerably less than from my vet

Rated 5 out of 5 stars
By Happy1 on Feb 21, 2023

Excellent product

When used as directed I had great results. My dog is 17 years old and was losing ground. He really bounced back.

Rated 1 out of 5 stars
By B1234 on Jan 14, 2023

Not good, cat kept throwing up

My vet recommend Denamarin. My cat kept throwing up multiple times a day after giving this. I discontinued and there have been no more issues.

Rated 1 out of 5 stars
By Delru on Nov 7, 2022

Hard Pills

Always buy the chewables, which my small dog loves. These have to be shoved down your small pet's throat. No use trying to wrap in a piece of food, as it will be spit out. The chewables for all dogs hasn't been available for MONTHS. No excuse, no reason. Going to find something else other than Denamarin.