Orbax Tablets for Dogs & Cats, slide 1 of 1

Orbax Tablets for Dogs & Cats

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Strength: 68-mg
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Count: 1 tablet

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Orbax (orbifloxacin) is a fluoroquinolone antibiotic used in the treatment of diseases in dogs and cats associated with bacteria susceptible to orbifloxacin. It comes in a tablet form, which means it's easy to feed to your pet. Simply feed it like a treat, disguise it in a pill pocket or hide it in normal meals. It's also available in an oral liquid.

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Orbax (orbifloxacin) is indicated for the treatment of urinary tract infections (cystitis) in dogs. This medication is also indicated for skin and soft tissue infections (wounds and abscesses) in dogs and cats.

Possible Side Effects

Side effects that usually are not serious include:

  • Vomiting, diarrhea, nausea, reduced appetite.

You don’t have to be overly concerned if you see any of these effects unless they are severe, worsen, or continue to be a problem. Contact your veterinarian if this happens.

Side effects that may be serious or indicate a serious problem:

  • Trouble walking (or other joint effects), especially in young or growing animals.

*Stimulation (eg, overly excited) or seizures (rare), especially in animals with liver or kidney problems.

*Blindness in cats can be caused by large doses.

*Fever, rashes, or trouble breathing may indicate an allergy to the drug.

*Decreased or lack of an appetite, especially in cats.

If you see any of these signs, contact your veterinarian immediately.

Drug & Food Interactions

Orbifloxacin and other antibiotics have been shown to cause joint disease in young pets of most species tested, the dog being particularly sensitive to this side effect. Orbifloxacin is contraindicated in young pets during the rapid growth phase (between two and eight months of age in small and medium-sized breeds, and up to 18 months of age in large and giant breeds). Orbifloxacin is contraindicated in pets known to be hypersensitive to antibiotics.


Prescribing antibacterial drugs in the absence of a proven or strongly suspected bacterial infection is unlikely to provide benefit to treated animals and may increase the risk of the development of drug-resistant animal pathogens. The use of fluoroquinolones in cats has been reported to adversely affect the retina. Such products should be used with caution in cats. Blindness has also been reported post-approval in cats. In some cases, blindness has been temporary. DO NOT EXCEED 3.4 mg/lb (7.5 mg/kg) BODY WEIGHT PER DAY IN CATS. Quinolones should be used with caution in animals with known or suspected central nervous system (CNS) disorders. In such animals, quinolones have, in rare instances, been associated with CNS stimulation which may lead to convulsive seizures. Quinolones have been shown to produce erosions of cartilage of weight-bearing joints and other signs of arthropathy in immature animals of various species.Administer orbifloxacin with caution in the presence of hepatic insufficiency/ impairment. The safety of orbifloxacin in animals that are used for breeding or that are pregnant and/or lactating has not been demonstrated. WARNINGS: For use in animals only. Do not exceed 7.5 mg/kg body weight per day in cats. Keep out of the reach of children.

This item is excluded from the first-time Autoship promotion.

Please note product may arrive in a Chewy Pharmacy vial, manufacturer packaging is shown for reference.

Also available in an oral solution.

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  1. Prescribing Information

See all items by Orbax

  • Item Number
  • Common Brand Name(s)
  • Generic Name
  • For Use With
    Dogs & Cats
  • Administration Form
  • Product Form
  • Health Condition
    Urinary Tract Infections (UTI), Skin Infections, Wounds
  • Drug Type


Recommended Dosage

The Orbax (brand of orbifloxacin) Tablets dose is 2.5 mg/kg to 7.5 mg/kg of body weight administered orally once daily for up to a maximum of 30 days of therapy, if necessary. Treatment of skin and associated soft tissue infections should continue for two (2) to three (3) days beyond the cessation of clinical signs. Treatment of urinary cystitis should be for at least ten (10) consecutive days with diagnosis and treatment re-evaluation if improvement is not seen within the first five (5) days.

Storage Instructions

Store between 36° - 86°F. Protect from excessive moisture.


What is Orbax?

Orbax is an oral medication that treats bacterial infections.

What are the benefits of Orbax?

  • Absorbs rapidly into the body.
  • Once a day medication.
  • No reported side effects.
  • Easy to administer.

How is this medication given?

Orally. Provide plenty of fresh water for your pet to drink.

How does this medication work?

It works by blocking the bacteria's ability to make DNA, resulting in death of the bacteria.

What results can I expect?

Orbax is well absorbed from the intestinal tract and is carried by the bloodstream to many tissues of the body where it kills susceptible bacteria. To be effective, Orbax must be given multiple days in a row. If condition does not improve or worsens after beginning treatment, please consult your veterinarian.

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  • 5 out of 5 stars


    By Lateefa on Sep 4, 2021

    I have only used Chewy twice. I plan to use them in the future. They make it easy to work with my vet and get the products I need as quick as possible.

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  • 4 out of 5 stars

    tooth abscess

    By Noway on Oct 28, 2019

    i will try this on my dogs abscessed tooth. this is the second antibiotic i have tried.

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