PancrePlus Tablets for Dogs & Cats, 425-mg, 1 tablet
Prescription Item
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PancrePlus is prescribed as a digestive aid and replacement therapy for pets whose digestion of proteins, carbohydrates and fats are affected by exocrine pancreatic insufficiency (EPI).
UsesFor use as a digestive aid in replacement therapy where digestion of protein, carbohydrate and fat is inadequate due to exocrine pancreatic insufficiency.
Possible Side EffectsSome pets may exhibit reactions, such as allergic reaction (difficulty breathing; swelling of the lips, tongue or face; hives), diarrhea or loose stool. If you observe any of these side effects, contact your veterinarian as soon as possible.
Drug & Food InteractionsTalk to your veterinarian about any other drugs your dog is taking before starting this medication.
Precautions
Discontinue use in animals with symptoms of sensitivity.
Also available in a powder.
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Item Number146840
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Common Brand Name(s)PancrePlus, PanaKare Plus
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Generic NamePancreatic Enzyme Concentrate
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For Use WithDogs & Cats
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Administration FormOral
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BrandVetOne
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Product FormTablet
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Health ConditionExocrine Pancreatic Insufficiency (EPI)
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Drug TypeEnzyme
Lipase, Protease, Amylase
Dogs: 2/3 tablets per meal. Cats: 1/2 - 1 tablet per meal. The dose is administered before each meal. Estimate dose according to the severity of the condition and weight of the animal.
Storage InstructionsStore tightly closed container in a dry place at room temperature.
What is PancrePlus?
PancrePlus is used as a digestive aid in replacement therapy where digestion of protein, carbohydrates and fat is inadequate due to exocrine pancreatic insufficiency.
What are the benefits of PancrePlus?
- Enzyme replacement therapy to improve quality of life for pets with deficient exocrine pancreatic secretions.
- Can be used for dogs and cats.
- FDA approved.
How is this medication given?
For dogs, mix 3/4 to 1 teaspoon with each meal. For cats, mix 1/4 to 3/4 teaspoon with each meal. Mix well with moistened food (canned or dry) and leave at room temperature for 15-20 minutes prior to feeding. Give this medication exactly as directed by your veterinarian.
How does this medication work?
PancrePlus contains pancreatic enzymes which help to digest fat, protein and sugars. It is mixed with food prior to each meal.
What results can I expect?
Improves quality of life for pet's suffering with deficient exocrine pancreatic secretions.
Customer Reviews

100% Recommend
100% of reviewersrecommend this product
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4 Reviews
4 Reviews
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Saved my cat!
By PankyPlus on Nov 15, 2020
One of my cats, Penny Lane, has had a heck of a year. She was diagnosed with IBD, EPI, and a poultry allergy this summer. We initially tried the vet-preferred powder since it’s ideally consumed on food. We had a heck of a time trying to sneak it into her food at first. Penny’s no fool. We initially had some success mixing in Churu treats and syringing it into her mouth after eating. We were then eventually able to just feed spiked Churu treats in a bowl with food. Both methods ended up getting very expensive since she needs it at least twice a day. Fortunately for our wallets, she eventually grew tired of it. It took some getting used to, but after pilling her for a few months, she’s used to One of my cats, Penny Lane, has had a heck of a year. She was diagnosed with IBD, EPI, and a poultry allergy this summer. We initially tried the vet-preferred powder since it’s ideally consumed on food. We had a heck of a time trying to sneak it into her food at first. Penny’s no fool. We initially had some success mixing in Churu treats and syringing it into her mouth after eating. We were then eventually able to just feed spiked Churu treats in a bowl with food. Both methods ended up getting very expensive since she needs it at least twice a day. Fortunately for our wallets, she eventually grew tired of it. It took some getting used to, but after pilling her for a few months, she’s used to it. I think she now associates this with feeling better because we don’t even struggle to get it into her—she eats it right out of our hands like a treat. (She’s allergic to chicken, so pill pockets were a no-go!) She may get fussy later on and need a piller, but this is working out well for her now. She’s gained weight and has much better stool. The family now calls these Panky Plus Pills. Of the other medications she needs, this one is the easiest for both her and the humans. Yay. … more
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Great for EPI
By Jrose on Jun 3, 2019
I use these for my GSD that has EPI. 1 tablet per cup of food + 1 for the bowl. I feed him 4 times a day and it works GREAT. I have found that they should be crushed though, mix with a little water and sit for about 5 minutes. They are cheaper than the powder. The PancrePlus along with B12 and monitoring his Poo....he went from a skinny 74 pounds to 102 pounds and healthy.
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Sam the cat is so much better
By SamsMom on Apr 29, 2019
Our cat Sam apparently has Exocrine Pancreatic Insufficiency. He will eat voraciously but he has suffered catastrophic weight loss. He was literally starving in front of our eyes. After taking the PancrePlus tabs for a month now, he has gained weight and strength. Our vet says there is a powdered product that is given mixed with the food, that is very expensive, and that giving these PancrePlus tabs is a more economical option. What I love about the tabs is: I know my cat can take a tablet, but if I mix something in his food, he may or may not eat it. Plus, if he swallows the tab before he eats, he will not get any of the medicine on his nose. He does not need to have irritating residue Our cat Sam apparently has Exocrine Pancreatic Insufficiency. He will eat voraciously but he has suffered catastrophic weight loss. He was literally starving in front of our eyes. After taking the PancrePlus tabs for a month now, he has gained weight and strength. Our vet says there is a powdered product that is given mixed with the food, that is very expensive, and that giving these PancrePlus tabs is a more economical option. What I love about the tabs is: I know my cat can take a tablet, but if I mix something in his food, he may or may not eat it. Plus, if he swallows the tab before he eats, he will not get any of the medicine on his nose. He does not need to have irritating residue of medicine on his tender nose. … more
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Exocrine Pancreatic Insufficiency
By Rebecca on Sep 29, 2018
This enzyme has worked very well for my German Shepherd. He was starving, and now is of good weight.