PetAlive EaseSure-S Brain & Nervous System Support Dog & Cat Supplement, 2-oz bottle

By PetAlive
Rated 4.4737 out of 5 stars
$33.49Chewy Price
$39.95Chewy Price
$31.82Autoship Price
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About This Item


  • Non-addictive herbal supplement for brain and nervous system functioning in dogs and cats.
  • Supports the management of common symptoms of seizures, epilepsy, and stress-induced episodes by supporting an overactive nervous system.
  • Natural tonic promotes calm or stimulated nerves as needed and reduces involuntary muscle movements and twitching.
  • Crafted by experts to help calm or stimulate nerves as needed.
  • Comes in a convenient liquid drop form, so dosing can be adjusted to treat furry friends of all sizes. This can also be used with PetAlive's EaseSure-M homeopathic drops.

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Nutritional Information

Feeding Instructions


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Top IngredientsProprietary Formula, Passion Flower (Herb), Skullcap (Herb)...Active Ingredients: Citicoline, Coconut Oil, L-Theanine...Active Ingredients: Citicoline, Coconut Oil, L-Theanine...Active Ingredients: L-Carnitine, Alpha Lipoic Acid, L-Leucine...Beef Liver, Chia Seeds, Kelp...
Breed SizeExtra Small Breeds, Small Breeds, Medium Breeds...Extra Small Breeds, Small Breeds, Medium Breeds...Extra Small Breeds, Small Breeds, Medium Breeds...Extra Small Breeds, Small Breeds, Medium Breeds...Small Breeds, Medium Breeds, Large Breeds
Health FeatureBrain HealthBrain Health, Vitamins & MineralsBrain Health, Vitamins & MineralsBrain Health, Senior CareBrain Health, Digestive Health, Vitamins & Minerals...
LifestagePuppy, Kitten, Adult, SeniorPuppy, Adult, SeniorAdult, SeniorSeniorAdult
Food FlavorUnflavoredFruits & VegetablesFruits & VegetablesUnflavoredBeef
Food FormSupplementSupplementSupplementSupplementPowder
Special DietNo Corn No Wheat No Soy, Organic, Non-GMO

Questions & Answers

22 Customer Questions

Do I just give this to my dog when hes having a seizure..or everyday
Answer by ChewyMay 07, 2018
The Supplement can be given for maintenance daily or when needed.

What does it do
Answer by ChewyMar 23, 2018
EaseSure-S is a 100% safe, herbal supplement that supports symptoms commonly associated with epilepsy, seizures, or stress-related episodes in pets with an overactive nervous system. Using a scientific blend of ingredients known to support soothed nerves and natural equilibrium, the concentrated liquid formula promotes nervous system health, stability, and brain function.

I read elsewhere on website that because of formula changes, it is recommended to use both Easesure-S along with E asesure-M to control seizures - is that correct or has owners with pets seen that using Easesure -S works well by itself?
Answer by ChewyDec 17, 2019
This can also be used with PetAlive's EaseSure-M homeopathic drops but it is not required.

Should the product be stored in the refrigerated after opening?
Answer by ChewyMar 24, 2023
This supplement does not need to be refrigerated after opening.

ReviewsWrite a Review

Rated 4.4737 out of 5 stars
57 Ratings
Would recommend to a friend

57 Customer Reviews

Rated 5 out of 5 stars
By Scubagirl on May 4, 2023

Works with higher dosage

I had bought this a few months ago for my cat who has regular seizures. At first I was giving him about .25 ml per day. His seizures calmed to about 1 every 3 weeks and then it changed. It was back to weekly so I stopped the drops thinking they weren't working. After a couple of months his seizures increased to every week for about a month. He had never had them that often. So I decided to start giving him .50ml daily after his last seizure on 4/3/23. As of today,5/3/23, there have been no seizures. About 4 weeks. Hopefully this is a trend. To go from weekly to none is pretty amazing.

Rated 5 out of 5 stars
By Bren on Apr 18, 2023

Works great!

I can't say enough good things about this stuff. My cat (almost 6 yr old) cat has been having seizures for 4 years. In that time they have progressed in both intensity, and amount. Sometimes several major seizures a day. They were bad! He was on phenobarbital, but it never really worked and I had to have continual blood work on him. Within a few days of taking this, his seizures are virtually gone!

Rated 5 out of 5 stars
By ItsCC on Apr 24, 2023

Product information

The product came on time and sealed. Upon opening I noticed a black oily resin at the top or the bottle and in the syringe, I contacted the company and this is NORMAL it’s just plant resin from the herbs. Just shake it up really good to break it down.

Rated 5 out of 5 stars
By Alice on May 11, 2023

Pet alive CBD oil

It is easy to use. Unfortunately, I was not able to use it very long. Maybe if I started it sooner I would have had a better outcome.

Rated 5 out of 5 stars
By Mama3 on Jan 10, 2023

My baby has mini seizures

Chewy is always fab fast shipping my baby has little seizures I've only been using this for less than one month I think it must taste bad because I have to fight him to take it lol ! I drop three drops right on his gums to make sure he gets it !! So far so good !!

Rated 1 out of 5 stars
By grayce on Feb 16, 2023

black sludge

black sludgey gunk built up on the dropper.. does not look safe to be giving to my baby. packaging was not very good, would like my money back:/

Rated 5 out of 5 stars
By Lisa on Sep 23, 2022

Works great for collapsed trachea

My 10 lb 16 yr old yorkie has had collapsed trachea for over a year and slowly getting worse.I gave this 5 stars because it worked amazingly for that .unfortunately after a month of using it I had to bring him to vet for a scabby rash on his back ,which he was given antibiotics for.I wasn't sure what was causing it but I'm pretty sure its the ease sure. I'm so sad about it because he seemed so much better on this ,even just taking 4 drops a day.hopefully we can find something else more natural to help him

Rated 5 out of 5 stars
By Carolyn on Oct 25, 2022

Excellent results

We have been using EaseSure for our 15 year old Chihuahua who has epilepsy. This product is amazing and can stop her seizures in less than 5 minutes! We only give when she is having a seizure so it lasts us for almost a year. Excellent product!

Rated 5 out of 5 stars
By Janet on Feb 27, 2023

For my dog with DM.

Love Chewy! Very fast service, Never have to wait on an order.

Rated 5 out of 5 stars
By Katherine on Oct 3, 2022

Answer to prayer!

After my boy, Wolf, had some seizures two weeks apart, I decided to try something homeopathic. I talked to his vet and he agreed it was worth a try. Wolf sees it as a treat and willingly takes it twice a day. So far, no more seizures. I recommend giving it a try!