An endocrine disorder, pituitary pars intermedia dysfunction (PPID)—also known as Cushing’s disease—is known to affect over 20% of older horses and ponies, generally over the age of 15 years old. Prascend Tablets for Horses is a dopamine receptor agonist that works to help control the signs of PPID in your horse. Unmanaged Cushing’s disease in your horse can impact her overall health and wellbeing, including weight loss and delayed shedding. Meanwhile, Prascend Tablets for Horses can offer you an easy and effective way to help manage symptoms, while also helping to treat the pain and discomfort associated with Cushing’s disease.
For the control of clinical signs associated with Pituitary Pars Intermedia Dysfunction (Equine Cushing's Disease) in horses.
Possible Side Effects
To read more about possible side effects, please review the package insert.
Drug & Food Interactions
Pease consult with your veterinarian for any Food and Drug interaction concerns.
Treatment with PRASCEND (pergolide tablets) may cause inappetence. The use of PRASCEND in breeding, pregnant, or lactating horses has not been evaluated. The effects of pergolide mesylate on breeding, pregnant, or lactating horses are not known; however, the pharmacologic action of pergolide mesylate suggests that it may interfere with reproductive functions such as lactation.
PRASCEND is approximately 90% associated with plasma proteins. Use caution if administering PRASCEND with other drugs that affect protein binding.
Dopamine antagonists, such as neuroleptics (phenothiazines, domperidone) or metoclopramide, ordinarily should not be administered concurrently with PRASCEND (a dopamine agonist) since these agents may diminish the effectiveness of PRASCEND.
Keep PRASCEND in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. Dogs have eaten PRASCEND tablets that were placed in food intended for horses or dropped during administration of the tablets to the horses. Adverse reactions may occur if animals other than horses ingest PRASCEND tablets.
PRASCEND is contraindicated in horses with hypersensitivity to pergolide mesylate or other ergot derivatives.
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