Prascend (Pergolide) Tablets for Horses, slide 1 of 1

Prascend (Pergolide) Tablets for Horses, 1 mg, 1 Tablet

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An endocrine disorder, pituitary pars intermedia dysfunction (PPID)—also known as Cushing’s disease—is known to affect over 20% of older horses and ponies, generally over the age of 15 years old. Prascend Tablets for Horses is a dopamine receptor agonist that works to help control the signs of PPID in your horse. Unmanaged Cushing’s disease in your horse can impact her overall health and wellbeing, including weight loss and delayed shedding. Meanwhile, Prascend Tablets for Horses can offer you an easy and effective way to help manage symptoms, while also helping to treat the pain and discomfort associated with Cushing’s disease.


For the control of clinical signs associated with Pituitary Pars Intermedia Dysfunction (Equine Cushing's Disease) in horses.

Possible Side Effects

To read more about possible side effects, please review the package insert.

Drug & Food Interactions

Pease consult with your veterinarian for any Food and Drug interaction concerns.


Treatment with PRASCEND (pergolide tablets) may cause inappetence. The use of PRASCEND in breeding, pregnant, or lactating horses has not been evaluated. The effects of pergolide mesylate on breeding, pregnant, or lactating horses are not known; however, the pharmacologic action of pergolide mesylate suggests that it may interfere with reproductive functions such as lactation. PRASCEND is approximately 90% associated with plasma proteins. Use caution if administering PRASCEND with other drugs that affect protein binding. Dopamine antagonists, such as neuroleptics (phenothiazines, domperidone) or metoclopramide, ordinarily should not be administered concurrently with PRASCEND (a dopamine agonist) since these agents may diminish the effectiveness of PRASCEND. Keep PRASCEND in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. Dogs have eaten PRASCEND tablets that were placed in food intended for horses or dropped during administration of the tablets to the horses. Adverse reactions may occur if animals other than horses ingest PRASCEND tablets. PRASCEND is contraindicated in horses with hypersensitivity to pergolide mesylate or other ergot derivatives.

  1. Package Insert

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  • Item Number
  • Administration Form
  • For Use With
  • Generic Name
  • Brand
    Boehringer Ingelheim
  • Product Form
  • Health Condition
  • Drug Type


Recommended Dosage

Administer PRASCEND (pergolide tablets) orally at a starting dose of 2 mcg/kg once daily. Dosage may be adjusted to effect, not to exceed 4 mcg/kg daily. The tablets are scored and the calculated dosage should be provided to the nearest one-half tablet increment. See prescribing information for more dosing instructions.

Storage Instructions

Store at 68F- 77 F (20-25 C). Excursions between 59 F- 86 F (15-30 C) are permitted.


Can Prascend be used in breeding, pregnant, or lactating mares?

PRASCEND has not been evaluated in breeding, pregnant, or lactating animals. As PRASCEND is a dopamine agonist, it may interfere with reproductive hormones involved in these groups of animals.

How long until I begin seeing improvement with my horse after beginning treatment with Prascend?

Depending on the specific clinical sign, improvement may be observed beginning within 30 days and continue through 6 months of initial treatment.

What is the benefit of FDA-Approval?

Obtaining FDA approval is a strict and rigorous process. PRASCEND is manufactured according to the strict specifications set forth by the US Food & Drug Administration. PRASCEND is manufactured to provide a consistent, safe, and efficacious product.

What is the best way to administer Prascend?

PRASCEND can be hidden in an apple or treat. The tablet may be administered orally by dissolving in a small amount of water, with or without sweetener. Administer the liquid with a syringe or as a top-dressing on feed. After dissolving, the tablet should be given immediately. PRASCEND should not be crushed due to the potential for increased human exposure. See package insert for full prescribing information.

What are the benefits of treatment with Prascend?

PRASCEND helps reduce the clinical signs of PPID and improve horses quality of life. Treatment with PRASCEND may cause loss of appetite. Most cases are mild.

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