PRN PHARMACAL Prozyme Powder Supplement for Dog & Cats, 454-g -

PRN Pharmacal Prozyme Powder Supplement for Dog & Cats

By PRN Pharmacal
Rated 4.4359 out of 5 stars

New Customers Only: Spend 49+ Get $20 Off With Code: WELCOME

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$38.84Chewy Price

In Stock
FREE 1-3 day shipping over $49

About This Item


  • Created and manufactured in the USA at a state-of-the-art facility using the highest-quality, holistic ingredients.
  • An all-natural combination of plant-derived digestive enzymes in a palatable powder form.
  • Convenient and affordable powder helps your dog or cat thoroughly and efficiently digest her food and support normal health.
  • Maximize your best friend's nutrition by improving her ability to absorb nutrients from her food.
  • The four included enzymes help break down protein, fat, carbohydrates and fiber; also helps address general gastrointestinal bowel concerns.

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Nutritional Information

Feeding Instructions


Questions & Answers

14 Customer Questions

Why should this be used under veterinary care....can something harmful happen?
Answer by ChewyJul 04, 2018
Do not use in animals with known hypersensitivity to any of the ingredients. This product is intended for intermittent or supplemental feeding only. Keep out of reach of children and pets.

How long can you have your dog use this ??
Answer by ChewyJan 16, 2020
ProZyme should be a part of every meal for the life of the animal.

Is this product free of gluten, soy, wheat, whey?
Answer by ChewyOct 14, 2022
For a complete list of ingredients and the guaranteed analysis, click the “Nutritional Information” tab on the product page.

Is there an expiration date on the Prozyme powfer?
Answer by ChewyJan 30, 2020
There is no required expiration date as long as it is stored as directed.

ReviewsWrite a Review

Rated 4.4359 out of 5 stars
39 Reviews
Would recommend to a friend

39 Customer Reviews

Filter by reviews that mention

Rated 2 out of 5 stars
By Krista on Jun 10, 2022

Cat wouldn't eat

I was excited about this product to help my cat absorb the food he is eating. He ate it for the first 3 times and after that he turned his nose at any food I attempted to sprinkle with this supplement. I thought I could use this for all my animals but they figured me out.

Rated 5 out of 5 stars
By Lola on May 7, 2022

Prozyme Powder

I mix the Prozyme powder in my little fur baby’s wet food twice a day. It is great for her digestive system. It must work because she is 18 years old and doing well.

Rated 5 out of 5 stars
By Kate on Oct 11, 2021

Prozyme additaive

I have used this product for over 20 years. It helps my dogs with digestion. No more gassy problems.

Rated 5 out of 5 stars
By Jewels on May 7, 2021

Digestive Enzymes is so important!

My boy Bentley ended up with a horrible case of pancreatitis after my husband bought him a big box of Pedigree DENTASTIX..................Please do not give these treats or other junky nasty treats, due to the fact that they are unhealthy & not safe. It was a horrible thing for him to go through & the cost has been unbelievably expensive. He is on a Low fat special food diet which is also costly. However this stuff has been a gamechanger! He has put most of his weight back on, & after months of sickness he is getting a little better. I am looking into starting him on some pre/pro biotics soon. Our vet says that people feed their pets the worst things possible & the treats in stores are so bad & cause all these problems, & he says use some fresh veggies if you must give your treats. I now use unsalted green beans & he loves them, a small piece/slice of carrots, & he love zucinni & pumpkin too. Fruit too like a chunck of apple, or some bluberries. I am going to make him some homemade healthy dog treats soon. Thank you CHEWY for your GREAT FAST shipping too!

Rated 5 out of 5 stars
By Jill on May 18, 2021

worked right away!

My puppy had been persistently having loose stools (clear fecal float as well) and this fixed him right up. We tried pumpkin and probiotics with no noticeable results first. Could tell the difference within a day or two!

Rated 5 out of 5 stars
By Aimee on Mar 17, 2021

I love this stuff!

I have been using Prozyme for over 10 years now. It was first recommended to me by my vet for my Brittany/Aussie mix, as she had gas and many other issues. It helped her so much that I have continued to give it to all of my dogs. I now have 4 dogs on this - mostly Border Collies/ Aussies/ and a Sheltie. I have absolutely no digestive issues with any of them, and - as a bonus - all of my dogs are ridiculously soft!!!! I have farm dogs that do not get groomed :)

Rated 5 out of 5 stars
By Zach on Mar 25, 2021

amazing product life changer for sensitive stomach

I can’t say enough how much this has helped my female malamute. She has always had digestive troubles since she was a pup and is been an endless job trying to solve them. I’ve been through 5 different foods and ended up on a prescribed hydrolyzed diet with only moderate success. Even on this diet she would still have bad days and when it was good seemed like the food kinda slowed down her digestive tract and she had smaller stool it just wasn’t great. After starting this probiotic I started seeing results in about 3-4 days she was starting to eat more regularly as well as use the bathroom more regular and for the first time in a long time she was having regular full size solid stools. I know that probably seems like nothing to most people but for her it was like a thousands pounds taken off our shoulders. About 10 days in now and she has been regular and having healthy stool consistently the whole time! Seriously if you’re considering giving this a try just do it I’m sure it’s no miracle cure but it has been a great solution to my girls problems and we are currently transitioning back to her preferred kibble with absolutely no problems thus far. That means no more 100$ bags of food for me and no more bland kibble for her. I just pray my success continues but this has helped so much.

Rated 1 out of 5 stars
By Corinne on Feb 5, 2021

Made my cat sick

After ingesting the Prozyme, my cat severely threw up for 24 hours and rushed him to the vet. Chewy was kind enough to refund the purchase price within 3 days. I believe he is lactose intolerant, since after trying a lactose-free brand, he did not throw up.

Rated 4 out of 5 stars
By BMW1978 on Apr 22, 2021

Waiting to see

I've only had this item a week. Waiting to see if there is a notable difference in my senior dog.

Rated 3 out of 5 stars
By Buggy on Nov 11, 2020

It kinda helped

So about a year ago my dog Luna was diagnosed with EPI. Before her diagnosis she was 65lbs and she was eating and drinking water like crazy! She then slowly stopped eating so I figured maybe she wants soft food so I put warm water in her hard food to soften it up and she starting eating a bit more. After about a week she stopped eating again and that’s when it all started happening she started dropping weight like crazy (she lost 20lbs in a week waiting for the vet appointment) and was always tired or laying down (she was at the time about a year and a half so she was all spunk before it happened) and started to scavenge for other things for “food.” So I made an appointment to the vet and they thought maybe it was worms and all those tests came out clear. Her next test was a blood test which came out for EPI! I was stressed like crazy and the vet recommended me to these! They definitely helped with her weight but not back to her healthy weight, she’s gotten some of her spunk back it’s still like this (almost a year later) she has her ups and downs still her poops are slowly getting solid again but I’ve been thinking about switching to a new enzyme to see if it’ll be better for her. I definitely recommend it for others but for my 2 year old pup it only helped to an extent.