Purina Pro Plan Veterinary Diets Calming Care Liver Flavored Powder Calming Supplement for Dogs, 30 count

By Purina Pro Plan Veterinary Diets
Rated 3.9695 out of 5 stars
$33.99Chewy Price
$32.29Autoship Price
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Purina Pro Plan Adult Sensitive Skin & Stomach Salmon & Rice Formula Dry Dog Food, 30-lb bag
Rated 4.1136 out of 5 stars
$71.98Chewy Price

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About This Item


  • Features a strain of probiotic known as BL999 to help your canine companion stay calm.
  • A great option for pups who exhibit anxious behaviors like excessive barking, pacing, jumping and spinning.
  • Helps dogs cope with external stressors.
  • Helps canine companions maintain positive cardiac activity when stressed.
  • Can help promote positive emotions and a healthy immune system.

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Nutritional Information

Feeding Instructions


Play Video: Learn More About Purina Pro Plan Veterinary Diets From Our Team of Experts
Learn More About Purina Pro Plan Veterinary Diets From Our Team of Experts

About Purina Pro Plan Veterinary Supplements for Dogs

Supplements You Can Trust

From gastrointestinal and immune health to anxious behaviors, find support for your pet with Purina Pro Plan Veterinary Supplements. Trusted by veterinarians, every supplement is backed by research, including Purina’s line of probiotic supplements that represents their leadership in the field of microbiome research.

Easy to Administer

Each supplement was designed to be effective and easy to give your pet via powder sachets or chewable tablets.

Made by Experts

Pro Plan Veterinary Supplements are developed by a collaborative network of scientists, veterinarians and nutritionists.

Exceptional Quality

In a typical shift, Purina conducts 400+ quality checks on ingredients, packaging, receiving, processing, and packing.

Responsible Sourcing

Each ingredient can be traced back to its trusted supplier, so quality may be evaluated all the way back to the source.

About Purina Pro Plan Veterinary Supplements

Purina Pro Plan Veterinary Supplements is committed to the health of every pet, especially those with unique needs. These advanced supplements are backed by decades of research and supported by a global network of scientists. This knowledge and experience have laid the groundwork for innovative supplements that are trusted by pet owners and veterinary professionals alike.

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Top IngredientsActive Ingredients: Bifidobacterium longum BL999 1x109 CFU., Inactive Ingredients: Liver flavor, Maltodextrin. B-2519....Passion Flower, Valerian Root Extract, Magnesium...Active Ingredients: L-Tryptophan, Valerian Root Extract (Valeriana Officianlis), Ashwaganda Extract (Withania Soniferum)...Active Ingredients: Hemp Seed Powder, Valerian Root, Hemp Seed Oil...Active Ingredients: Gaba (Gamma-Aminobutyric Acid), L-Theanine, Passionflower Extract (Aerial Parts)...
Breed SizeSmall Breeds, Medium Breeds, Large BreedsSmall Breeds, Medium Breeds, Large BreedsExtra Small Breeds, Small Breeds, Medium Breeds...Extra Small Breeds, Small Breeds, Medium Breeds...Small Breeds, Medium Breeds, Large Breeds
Health FeatureCalmingCalmingCalmingCalming, Hip & Joint Support, Immune SupportCalming
LifestageAll LifestagesAdultAdult, SeniorPuppy, Adult, SeniorAdult
Food FlavorMeat, LiverUnflavoredPoultry, DuckChicken
Food FormFood Topping, SupplementSupplementSupplementSupplementSupplement
Special DietNo Corn No Wheat No Soy, Non-GMO

Questions & Answers

38 Customer Questions

Can this be used for separation anxiety? And if so can it be used everyday, or only for a certain number of days.
Answer by ChewyAug 03, 2019
This supplement has shown to help keep dogs calm during stressful situations like separation, trips to the vet, thunderstorms and more.

Where is this produced and what is the source (country) of the ingredients?
Answer by ChewyJul 15, 2019
The product is made in the United States. The high-quality ingredients are sourced within the United States, depending on availability.

How long will it take to see a reduction in anxiety?
Answer by ChewyAug 14, 2019
This supplement is to be administered daily to build up in your dog's system. It may take six weeks to see results, or sooner depending on your dog.

does this need RX?
Answer by ChewyJul 18, 2019
This supplement does not require a prescription, however it is recommended to use under the supervision or direction of your veterinarian.

ReviewsWrite a Review

Rated 3.9695 out of 5 stars
459 Ratings
Would recommend to a friend

457 Customer Reviews

Rated 5 out of 5 stars
By Chas on Sep 10, 2023

Life saver

We moved and my rescue did not handle the change well. She is a little anxious all the time, but was never this bad. Vet recommended going onto this supplement and We noticed a huge improvement within 2 weeks and now it has been 2 months and this is the least anxious I have ever seen her. So it is worth the investment for us. It completely took care of her symptoms

Rated 1 out of 5 stars
By Jules on Jul 28, 2023

made my poor girl so sick

At first, this only caused my pup to poop in the house a couple times (she never does that) which I was okay with as her system was as probably just getting used to being more regulated. But then, the second night my poor baby began to throw up again and again, dry heaving between, stressed and so sick. Will never give this to her again. Might work for some but not my baby.

Rated 5 out of 5 stars
By Cosmo on Jul 8, 2023

Recommended by Vets

We adopted a 6 year old anxious rescue with sound sensitivity and constant diarrhea. Our vet recommended this and we cannot believe the improvement in our dog. It does take at least 6 weeks to start seeing a change but he became less anxious/ stressed and the quality of his bowel movements increased dramatically. ( no more embarrassing messes and carrying a roll of paper towels on our walks!) Not only that but he LOVES the liver flavor. I sprinkle it on his food with a little bit of water and he looks forward to his special treat every morning.

Rated 5 out of 5 stars
By BB8 on Sep 2, 2023

As always, chewy has been a lifesaver. We found the probiotic calming product with chewy when it seemed like no one else had it. Would recommend chewy to everyone. Once again you guys came through. Thank you again.

Rated 1 out of 5 stars
By Faye on Aug 9, 2023

Didn't notice any difference

Didn't notice any difference in stool or anxious behavior when using. Waited until the end of using to rate, so over a month of use and no change. The regular forti flora would have been better to use (in my opinion) since that would have helped with stool, but vet recommended this.

Rated 5 out of 5 stars
By Olivia on Aug 28, 2023


I don't know if this stuff actually works or not. I have a nervous GSD. She's been taking this daily for a few months and I haven't noticed her being an calmer (what really makes her calm is a Thunder Shirt!).

Rated 5 out of 5 stars
By Doglover on Jun 13, 2023

Game Changer

A few months ago I adopted a 4 month old yellow lab from a hoarding situation. My little girl is so sweet, but she’s very whiny and very anxious. She loves to cuddle and get pets from everyone in the house, but when people would come over she would bark a lot and hide from them. I decided something needs to change. Looked into calming care and decided to give it a try. I noticed a change day 2 of giving it to her. After 2 weeks of giving her Calming Care we had a huge family party with over 50 people at our house. My little girl was welcoming to everyone. She let them pet her. People who have met her before were completely shocked by her calm welcoming behavior. I have been recommending this supplement to anyone who will listen. Seriously…Calming Care has been a game changer.

Rated 5 out of 5 stars
By Katie on Jun 20, 2023

Works on my 1 year old rescue hound.

When I rescued my hound at about a year old he was very anxious in the house, with new people, and on car rides. I asked the vet for suggestions and he suggested this and told me no real cons to it, even if it doesn't work its a probiotic and can help his poops so figured it was worth a shot. Been using it for about 2 months now. Between my pup being more comfortable at home, training, and this calming care, he is a totally different dog and so much more relaxed! He is so much happier now and is able to fully enjoy life! Will continue to use since minimal cons to the product.

Rated 5 out of 5 stars
By scphelps on Jun 23, 2023

Calming Love

This product was recommend to us by our vet. Our dog has bad separation anxiety, even if we leave her for 2 hours to go to the grocery store. She gets so worked up that her gut gets messed up and she won't eat for 2 days and she gets runny poo. With Purina Calming Care she still has separation anxiety, but her gut stays healthy and she can eat normally. One problem at a time. Thank you for this product.

Rated 4 out of 5 stars
By Earl on Jun 23, 2023

Subtle but present

The Purina Calming Care is very easy to provide as it comes in individual packets of a small amount of powder that you simply sprinkle on your dog's food each morning or evening. I can see a subtle improvement in my dog's anxiety level. A reduction in barking at everything she sees and a better focus.