ReBalance Antiprotozoal Oral Suspension for Horses, 1-qt

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Description

ReBalance is an oral suspension for horses with equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona. EPM is a nervous system disease that horses develop by ingesting contaminated feedstuffs with the protozoa Sarcocystis neurona. EPM presents highly variable clinical signs that may range from head tilt, ear droop, blindness, seizures, inability to chew or swallow, gait abnormalities, stumbling, muscle atrophy, weakness, incoordination, ataxia, or depression. Testing and development of an early, effective treatment plan should be considered.

Uses

ReBalance Antiprotozoal Oral Suspension is indicated for the treatment of horses with equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona.

Possible Side Effects

Side effects may included: Decreased appetite, loose stools, and mild colic.

Drug & Food Interactions

The use of ReBalance Antiprotozoal Oral Suspension is contraindicated in horses with known hypersensitivity to sulfonamide drugs or pyrimethamine.

Precautions

Prior to treatment with ReBalance Antiprotozoal Oral Suspension, EPM should be distinguished from the diseases that may cause ataxia in horses. Injuries or lameness may also complicate the evaluation of an animal with EPM. In most instances, ataxia due to EPM is asymmetrical and affects the front and/or the hind limbs. Treatment may cause generalized bone marrow suppression, anemia, leukopenia, neutropenia and thrombocytopenia. A complete blood count (CBC) should be performed monthly to monitor horses for development of these conditions. The administration of the drug may need to be discontinued and/or treatments for bone marrow suppression initiated. Worsened neurologic deficits (treatment crisis) may be observed during a period beginning with the first few days of treatment with ReBalance Antiprotozoal Oral Suspension and ranging out to 5 weeks. This neurologic deficit exacerbation may be the result of an inflammatory reaction to the dying parasites in the CNS tissue. The safe use of ReBalance Antiprotozoal Oral Suspension in horses used for breeding purposes during pregnancy, or in lactating mares has not been evaluated. The safety of ReBalance Antiprotozoal Oral Suspension with concomitant therapies in horses has not been evaluated.

  1. Prescribing Information

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  • Item Number
    178086
  • Generic Name
    Sulfadiazine/Pyrimethamine
  • Common Brand Name(s)
    Equisul-SDT, ReBalance
  • For Use With
    Horses
  • Brand
    PRN Pharmacal
  • Product Form
    Solution
  • Health Condition
    Equine Protozoal Myeloencephalitis (EPM)
  • Drug Type
    Antiviral
Ingredients
Ingredients

Sulfadiazine sodium; Pyrimethamine

Instructions
Recommended Dosage

ReBalance Antiprotozoal Oral Suspension is to be administered at a dose of 20 mg/kg sulfadiazine and 1 mg/kg pyrimethamine daily or 4 mL of ReBalance Antiprotozoal Oral Suspension per 110 lb. (50 kg) of body weight once per day. The duration of treatment is dependent upon clinical response, but the usual treatment regimen ranges from 90 to 270 days. Administer orally by suitable dosing syringe at least one hour prior to feeding with hay or grain. Insert nozzle of syringe through the interdental space and deposit the dose on the back of the tongue by depressing the plunger. Shake well before use.

Storage Instructions

Store at control room temperature 68°F - 77°F. Excursions permitted between 59°F - 86°F. Protect from freezing.

FAQ

What is ReBalance?

ReBalance Antiprotozoal is a medication prescribed to Horses with equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona.

What is EPM?

EPM is a nervous system disease that horses develop by ingesting contaminated feedstuffs with the protozoa Sarcocystis neurona.

EPM presents highly variable clinical signs that may range from head tilt, ear droop, blindness, seizures, inability to chew or swallow, gait abnormalities, stumbling, muscle atrophy, weakness, incoordination, ataxia, or depression. Testing and development of an early, effective treatment plan should be considered.

ReBalance, when administered under labeled conditions, is an FDA-approved, safe and effective treatment for horses with EPM caused by Sarcocystis neurona.

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  • 5 out of 5 stars

    Great purchase

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    Anyone who has horses knows treating a horse with EPM is pricey. Chewy out of all places is the cheapest I found this medicine and so glad I did. They ship faster than anyone I have ordered through.

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