Revolution Topical Solution for Dogs, 40.1-85 lbs

Prescription Item

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    $22.01 (22%)

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Count: 6 treatments
  • 3 treatments In stock
  • 6 treatments In stock

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Your furry friend must have a current heartworm test result on file with your veterinarian in order to be prescribed heartworm medication. Please visit your veterinarian to have this test performed annually to protect your four-legged friend. Revolution is a medication that is applied directly on your furry friend's skin to protect them from biting critters. When applied every 30 days, Revolution protects against heartworms, fleas, and ear mites. It's also effective in preventing and treating roundworms and hookworms in kittens and sarcoptic mange and American dog tick infestations in puppies.


Revolution is formulated to kill adult fleas and prevents flea eggs from hatching for one month. It is also indicated for the prevention and control of flea infestations, prevention of heartworm disease caused by Dirofilaria immitis, and the treatment and control of ear mite infestations. Revolution is also indicated for the treatment and control of sarcoptic mange and for the control of tick infestations due to Dermacentor variabilis.

Possible Side Effects

In safety studies, Revolution was administered at 1, 3, 5, and 10 times the recommended dose to sixweek-old puppies, and no adverse reactions were observed. When tested for oral ingestion at the recommended topical dose in 5 to 8-month-old beagles, no adverse reactions were observed. In a topical safety study conducted with avermectinsensitive collies at 1, 3 and 5 times the recommended dose of Revolution, salivation was observed in all treatment groups. Revolution also was administered at 3 times the recommended dose to heartworm infected dogs, and no adverse effects were observed. If side effects do occur, please contact your veterinarian immediately.

Drug & Food Interactions

Talk to your veterinarian about any other drugs your dog is taking before starting this medication.


Prior to administration of Revolution, dogs should be tested for existing heartworm infections. At the discretion of the veterinarian, infected dogs should be treated to remove adult heartworms. Revolution is not effective against adult D. immitis and, while the number of circulating microfilariae may decrease following treatment, Revolution is not effective for microfilariae clearance. Hypersensitivity reactions have not been observed in dogs with patent heartworm infections administered three times the recommended dose of Revolution. Higher doses were not tested. For use in animals only. Keep out of reach of children.

  1. Prescribing Information

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  • Item Number
  • Dosage Measure

    Use according to your veterinarian's instructions.

  • Generic Name


  • Common Brand Name(s)


  • For Use With


  • Brand


  • Breed Size

    Medium Breeds, Large Breeds

  • Product Form


  • Health Condition

    Fleas, Heartworms, Ear Mites, Ticks, Mange

  • Drug Type



Selamectin, Butylated Hydroxytoluene, Isopropyl Alcohol

Recommended Dosage

The recommended minimum dose is 2.7 mg selamectin per pound (6 mg/kg) of body weight.

Storage Instructions

Store at temperatures below 86°F.

  1. Remove the Revolution tube from its protective package.
  2. Holding the tube upright, firmly press the cap down until you hear a ‘click’ sound, which signals that the cap has punctured the applicator seal. Remove the cap and check to be sure that the tip of the tube is open.
  3. Part the hair on the back of the animal at the base of the neck, in front of the shoulder blades, until the skin is visible.
  4. Apply the tip of the Revolution tube directly to the skin. Squeeze the tube firmly 3–4 times in one spot until empty. Keep tube compressed on the final squeeze to avoid drawing liquid back into tube. Avoid contact between Revolution and your fingers.
  5. While keeping tube squeezed, drag it away from liquid and lift up to remove.
  6. Ensure tube is empty.

Do not massage Revolution into the skin. Do not apply when the haircoat is wet. Do not apply to broken skin – Revolution contains alcohol. Stiff hair, clumping of hair, hair discoloration, or a slight powdery residue may be observed at the site in some animals. These effects are usually temporary and do not affect the safety or effectiveness of the product.


What is Revolution?

Easy to apply, quick to dry, Revolution (selamectin) protects dogs against a variety of common internal and external parasites. Revolution is the first FDA-approved, topically applied medication for dogs 6 weeks and older that:

  • Prevents heartworm disease.
  • Kills adult fleas.
  • Prevents flea eggs from hatching.
  • Prevents and controls flea infestations.
  • Treats and controls ear mites.
  • Treats and controls sarcoptic mange.
  • Controls American dog tick infestations.

Revolution is quick-drying, nongreasy and waterfast, with no unpleasant odor, so you can cuddle and play with your dog as soon as the product dries. Bathing your dog 2 hours after application does not reduce the effectiveness of Revolution.

Revolution is a prescription-only medication available only through a veterinarian, not a pesticide registered by the Environmental Protection Agency (EPA).

How Revolution works?

Just one dose a month applied at the base of the neck in front of the shoulder blades is all your dog needs for protection against fleas, heartworms and other parasites. No pills. No sticky sprays. No more hassling with multiple products.

After application, Revolution enters the bloodstream through the skin. Concentrations of Revolution in the blood and tissues prevent heartworm disease. Revolution selectively redistributes from the blood to the skin, where it provides protection against fleas, flea eggs, American dog ticks and mites.

Is Revolution right for your dog?

Parasites are an annoying fact of life for our dogs. Parasites can cause a range of problems, from bothersome scratching to more serious medical issues, such as infections and dangerous or even deadly diseases. How dangerous these problems are depends on the type of parasite, the degree of infection or infestation, and your dog's reaction to the parasite.

Most parasites that affect dogs pose no risk for humans. However, a few parasites, like sarcoptic mange mites, are zoonotic, meaning they can be transmitted from animals to humans. Your veterinarian can recommend methods to prevent, treat or control many canine parasites to reduce the chance of human exposure and to keep your dog healthy.

Customer Reviews
28 Reviews 28 Reviews 4.8 out of 5 Stars

100% Recommend

100% of reviewersrecommend this product

4.8 / 5

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Showing 1-10 of 28 Reviews

  • Revolution works

    By on

    With good results for 10 years for our beloved Lab mix, Cody, We have chosen Revolution to prevent Fleas, Ticks and heartworm... all in one easy to apply dose over other products which treat flea & tick dose in one and then a separate heartworm medication. Our cost is slightly less, ordering is easier, (all requiring a vet prescription), and so is remembering to dose regularly and on time. Chewy has the best pricing and shipping to suit us.

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  • So Far, Everything is Looking Good

    By on

    Only 1 dose used so far, over half way till next, and flees are still gone. I was using K9 Adv**tix II and He**tG*rd Pro before switching. The He**tG*rd had been working, no problems there, but the Adv**tix stopped working over 6 months ago. I gave my boy a flee bath about 6 days before I applied Rev*luti*n. Flees would already be reappearing, at this point, with the previous product. I'll update this review if anything negative or strange starts happening, but so far I am happy with this purchase.

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  • No Mange Here

    By on

    This was suggested by a veterinarian specialist to ward off (and treat) mange. They say it doesn't give good tick coverage, but we can supplement for that. No mange since we started using it. We have a mangey (sp) fox problem in our area and ended up with a dog that was infected with it years ago. No more! This has done well by us! Definitely do your homework and ask your vet.

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  • Not for fleas

    By on

    I do not trust this for fleas but I use it for heartworm prevention with no problems for my golden retriever.He is on Bravecto for fleas.This combination works perfectly for us.Also I like that Revolution is easy to apply and dries fast.

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  • Quick and Efficient !

    By on

    It was a super smooth transaction. In the past I had many difficult times trying to get dogs heart worm and flea meds, this time with Chewy they called my vet and I received the medicine a few days later. Thankful for Chewy, I buy all my dog food from them too!

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  • Easy to keep your dog healthy

    By on

    Great stuff. So easy to apply to back of her neck once a month in the the comfort of home. No costly vet visit. Delivered right to my door. Easy Peasy

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  • A True Lifesaver...

    By on

    I had used Revolution for my former dog for over 13 years and early on with my present dog...and it truly does what it advertises! I had strayed a bit on my present dog and went cheaper and found my boy had fleas and 'scratchies' ALL the time because of me trying to save a buck or 2!? As much as I/We walk in the forest and come upon streams and what not...I need something that's going to meet all my boy's needs while being out in it! Thanks Again, Chewy!

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  • Great product

    By on

    My pet has been using this product for 12 years. It works well for her and she's never had a flee or heartworm problem so far.

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  • revolution

    By on

    great product , using this for years . also use the cat revolution and has always been great and not a lot of product on the animal where it drips off

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  • Right product you are looking for

    By on

    This is actually the first time I order Revolution on chewy. I normally order from another website but stump on here by accident and price is more reasonable. The delivery is much better than I expect and I get the item within a day. Seriously faster shipping than Prime. The medicine is exactly the same as I always get and have no problem with it.

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