Simparica Chewable Tablets for Dogs, 22.1-44 lbs

Prescription Item

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Count: 6 treatments
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  • 6 treatments In stock

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Simparica is a fast-acting oral flea and tick preventative prescription that begins killing fleas and ticks within hours of application. When applied every 30 days, it can prevent infestation of fleas as well as treat and control tick infestations including the Lone Star tick, Gulf Coast tick, American dog tick and brown dog ticks.


Simparica kills adult fleas, and is indicated for the treatment and prevention of flea infestations, and the treatment and control of tick infestations from lonenstar ticks, Gulf Coast ticks, American dog tick, black-legged ticks and brown dog ticks for one month in dogs 6 months of age or older and weighing at least 2.8 pounds.

Possible Side Effects

The most common side effects reported includes diarrhea and vomiting. Other side effects may include neurologic signs such as tremors.

Drug & Food Interactions

There are no known contraindications to the use of Simparica.


Simparica may cause abnormal neurologic signs such as tremors, decreased conscious proprioception, ataxia, decreased or absent menace, and/or seizures (see Animal Safety). The safe use of Simparica has not been evaluated in breeding, pregnant, or lactating dogs. NOT FOR USE IN HUMANS. KEEP THIS AND ALL DRUGS OUT OF REACH OF CHILDREN AND PETS. FOR USE IN DOGS ONLY. DO NOT USE SIMPARICA IN CATS.

  1. Prescribing Information

See all items by Simparica

  • Item Number
  • Dosage Measure

    Use according to your veterinarian's instructions.

  • Common Brand Name(s)


  • For Use With


  • Generic Name


  • Brand


  • Breed Size

    Small Breeds, Medium Breeds

  • Product Form

    Chewable Tablet

  • Health Condition

    Fleas, Ticks

  • Drug Type



Sarolaner, Hydrolyzed Soy Protein, Starch, Corn, Wheat Germ, Anhydrous Dibasic Calcium Phosphate, Corn Syrup, Gelatin

Recommended Dosage

Simparica is given orally once a month at the recommended minimum dosage of 0.91 mg/lb (2nmg/kg).

Storage Instructions

Store at or below 86°F.

Simparica can be offered by hand, in the food, or adminsitered like other tablet medications.

Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If a dose is missed, administer Simparica and resume a monthly dosing schedule.

Simparica should be administered at monthly intervals.

Flea Treatment and Prevention: Treatment with Simparica may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with Simparica can continue the entire year without interruption.

To minimize the likelihood of flea re-infestation, it is important to treat all dogs and cats withina household withan approved flea control product.

Tick Treatment and Control: Treatment with Simparica can begin at any time of the year.


How Does Simparica Work?

Simparica is a great tasting chewable tablet given orally once a month. It travels in your dog's blood to safely deliver persistent continuous protection against fleas and ticks from day 1 to day 35.

Why protect against fleas and ticks?

Tick-borne diseases represent a widespread and growing public health hazard to dogs (and their human companions), causing debilitating illness and even death. It only takes one tick to spread disease, so continuous protection is critical to help reduce the risk of infection.

Likewise, it only takes a single "pregnant" flea to start an infestation on a dog or in a home. And although fleas are largely perceived as a mere nuisance, they too, can pose health risks to pets and humans.

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  • Simparica chewable tablets

    By on

    Have been using Simparica, but have to drive 10 miles both ways to the Vet's office. We are elderly and this is much more convenient. Feel Simparica is a very good product.

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  • Great Product

    By on

    Great Flea Medication for Dogs who don't like taking a pill or owners who don't like the liquid treatments for flea prevention. My dog eats it just like a biscuit!

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  • great product

    By on

    This item came quick and easy with ease. Very safe and good for dog.

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  • Works!!!!!!!!!

    By on

    Works great for my Australian Shepard mix! Good brand

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