Simparica Trio Chewable Tablet for Dogs, 22.1-44.0 lbs, (Teal Box)

By Simparica Trio
Rated 4.5122 out of 5 stars
Prescription Item

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$34.98 Chewy Price
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$33.23Autoship Price

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FREE delivery
Usually arrives in 3-5 days
We'll collect your pet's prescription information at Checkout.

This item requires prescription approval.

Medications ship separately. Delivery times may vary.

About This Item


Help your furry friend fight off pests with Simparica Trio Chewable Tablets for Dogs! Every purchase comes with 6 treatments that are specially formulated for canine companions 8 weeks of age and older, weighing between 22.1 and 44 pounds. Simparica Trio is the first and only product that combines sarolaner, moxidectin and pyrantel in each treatment to help prevent heartworm disease, kill fleas before they can lay eggs, kill 5 types of ticks, treat and prevent flea infestations and treat and control roundworms and hookworms. And each monthly chewable tablet has a palatable liver flavor and can be taken with or without food!

Proudly sourced directly from the manufacturer or their approved distributor. Guaranteed genuine and backed by the manufacturer. One count orders of manufacturer-sealed blister packs will arrive in a resealable plastic bag.

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Play Video: Learn More About Simparica Trio From Our Team of Experts
Learn More About Simparica Trio From Our Team of Experts

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About Simparica Trio for Dogs

Enhance Your Dog’s Protection

Just 1 monthly Simparica Trio chewable provided 100% protection from heartworm disease in a study.


The only combination chewable proven to kill 5 types of ticks. Competitive chewable brands are only approved to kill 4.

Kills fleas before they can even lay eggs. Starts killing fleas within 4 hours, with 100% effectiveness achieved in 8 hours in a study.


Treats and controls roundworms and hookworms to protect dogs from intestinal parasites.

ReviewsWrite a Review

Rated 4.5122 out of 5 stars
369 Ratings
Would recommend to a friend

308 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 1 out of 5 stars
By Ariel on Nov 5, 2023

Dog is miserable now

We switched over to Simparica from Bravecto about a month ago, and I regret it 100%. My dog is now losing so much hair now, losing appetite, and had fleas within the 20 days of receiving her first dose. She started panicking and actually screaming when fleas were biting her, and we had to give her a flea bath to give her some quick relief. We have never seen her so distressed before, and it broke our hearts. She was previously on Bravecto and was doing great, but we switched so we could combine into one pill and cut down on cost, but now I may have just wasted ~$100. Currently trying to figure out how to get my money back.

Rated 5 out of 5 stars
By Marie on Dec 2, 2023

Works great.

The simpatico trio works great. It’s all in one and the dogs we owned have had no ill effects at all from this treatment. You put it online and order in advance it’s easy to obtain.

Rated 5 out of 5 stars
By Scott on Oct 29, 2023

I used their Pharmacy for the first time

It was a learning process but worth it. I did not know at first I had to mail in the prescription from the Vet I thought it would be like when I get a prescription but it was processed quickly once they received that.

Rated 5 out of 5 stars
By Laura on Nov 16, 2023

Works great

Our. Still recommended we switch. We are very pleased. Now I don’t worry about fleas, ticks, or worms. The dogs are free to run in the yard. And they chew it right up!

Rated 5 out of 5 stars
By Linda on Nov 16, 2023

Broad spectrum medicine

I really prefer this medicine because it covers a broad spectrum of bugs and worms. I just need one pill instead of multiple meds and my dog tolerates this very well.

Rated 5 out of 5 stars
By Michael on Oct 2, 2023

Veterinarian says they authorized a 6 month supply for both Dixie and Daisy back in June 2023 to you for a 6 month supply. I have 1 month left for Daisy (November’s dose) and none for Dixie! Can you check your records and verify that and send me the new doses for each (especially Dixie’s )

Rated 5 out of 5 stars
By David on Nov 23, 2023

Great Flea meds

My canine buddies enjoy the medication and tolerate it without side effects. I've treated my dogs for a couple of years now and they have no fleas.

Rated 5 out of 5 stars
By John on Nov 12, 2023

Good medication & Good service

My dog will take this medication better than other heart worm medications. I break the pill up and put peanut butter on pieces. Service from Chewy was easy and good.

Rated 5 out of 5 stars
By robynne on Nov 20, 2023

Excellent Service

This product is excellent but for some reason my dog won't eat it. These last two batches were different than before, but I crushed and give it to her.

Rated 5 out of 5 stars
By Kerry on Nov 18, 2023

Great product

I’ve been a long time user of Revolution but given the increase in tick cases my vet recommended we switch to this. Its easy to give and very effective.