SIMPLICEF (Cefpodoxime Proxetil) Tablets for Dogs, 200-mg, 60 tablets -

Simplicef (Cefpodoxime Proxetil) Tablets for Dogs

By Simplicef
Rated 4.5 out of 5 stars
Prescription Item

$243.00Chewy Price
$230.85Autoship Price
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About This Item


Simplicef tablets are prescribed by veterinarians for the treatment of various infections in dogs caused by gram-positive and gram-negative bacteria. Some of these infections include but are not limited to skin, urinary tract, bone, and respiratory tract infections. Best of all, this antimicrobial comes in a tablet form, so you can feed it by mouth.

Proudly sourced directly from the manufacturer or their approved distributor. Guaranteed genuine and backed by the manufacturer.

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Play Video: Learn More About Simplicef From Our Team of Experts
Learn More About Simplicef From Our Team of Experts

ReviewsWrite a Review

Rated 4.5 out of 5 stars
14 Reviews
Would recommend to a friend

14 Customer Reviews

Rated 5 out of 5 stars
By Gatsby on Jan 28, 2023

Simplicef 200mg

Cleared up my pup’s skin infection from a hot spot on his rump.

Rated 5 out of 5 stars
By Drew on May 29, 2022

Helps my cat (Vet approved)

My cat Duke generates lots of "sand" and crystals in his bladder that caused blockages downstream. Eventually at 9 yrs old the Vet put in implants that replace the blocked "tubing" from the kidneys to the bladder. The implants get flushed out monthly. Duke is now 11 yrs old. He gets some tough infections in his kidneys and implant areas which normal cat antibiotics could not control. So the Vet suggested trying this and it has worked well. Still need to treat Duke with it for 30 days to really kill the infection.

Rated 5 out of 5 stars
By BanditsMom on Mar 9, 2022

Great Company that cares about Animals!

Ordered Friday, Delivered Sunday! 2 Days after I ordered my dogs ear medication, had vet approval, shipped out, and in my hands!! I can't say enough great things about this company. Tried other pet pharmacy's and they took a week to get meds to me. This is my Go To for everything from now on! You will not be disappointed!! Thanks so much Chewy!!!

Rated 5 out of 5 stars
By Awesomesauce on Mar 20, 2022

Great company

Such a great drug for dogs skin diseases thanks. I can't wait to not have to use it but at least it works faster than others..

Rated 3 out of 5 stars
By Cheyennesmom on May 7, 2021

worked in the beginning

Cheyenne had a skin infection and took Simplicef for 10 days it was working great she was almost cleared up. But on the refill, there was a gap of about a week she didn't have any meds. I don't know if chewy was slow in sending the request or the vet was slow to respond but it flared up worse than before and the second round didn't help at all. So now she's on a different antibiotic.I believe it would have been fine if it didn't take so long to get the refill.

Rated 5 out of 5 stars
By Char on Sep 9, 2021

Great antibiotic!

My dawg’s skin healing! Yahoo. Great meds. Thank you Chewy!

Rated 5 out of 5 stars
By Daisy on Mar 18, 2021

They weren’t for my dog.

I purchased this because I was trying to buy items on a wish list for an animal rescue site in NJ, the Montclair animal revue. They care so much about the animals and as most rescues they need specific items when they get whole litter of puppies and kittens. Liz rocks it!!!

Rated 1 out of 5 stars
By Zip22 on Apr 13, 2021

Won’t divide pills

I ask if you would divide pills, sine my dog can only take 1/4 dose of this. You advised you dont

Rated 5 out of 5 stars
By Sammi on Mar 22, 2020

Great Medicine

This works great for my girl and happy I can order it from Chewy

Rated 5 out of 5 stars
By Sarah on Oct 21, 2019

Excellent Product

My dog has and will be on Simplicel for a long time for a chronic illness. He has tolerated it well. Price is cheaper than other medicines.