Spironolactone / Hydrochlorothiazide (Generic) Tablets, 25-mg

Specifications

Uses

Spironolactone Hydrochlorothiazide may be used in pets with congestive heart failure (CHF) who do not adequately respond to diuretics and ACE inhibitors (used primarily for the treatment of hypertension and congestive heart failure), or who develop hypokalemia (low levels of potassium in blood) on other diuretics and are unwilling or unable to supplement with external potassium sources.

Possible Side Effects

Please contact your veterinarian if you notice any of the following reactions: dehydration with excessive thirst and decreased urine production, or electrolyte imbalances, possibly with weakness, lethargy, restlessness, stumbling, dizziness, muscle pain or cramping, lack of energy, vomiting and diarrhea.

Drug & Food Interactions

Spironolactone and hydrochlorothiazide tablets should not be used in pets with acute or severe kidney failure, severe renal insufficiency, significant impairment of renal excretory function, hypercalcemia (high calcium levels), hyperkalemia (high potassium levels), Addison’s disease, and in pets who are allergic to diuretics or to other sulfonamide-derived drugs.

Precautions

Spironolactone Hydrochlorothiazide should not be used in pets with hyperkalemia (high potassium levels), Addison’s disease, kidney failure, severe renal failure or significant renal impairment. It should be used cautiously in animals with hepatic (liver) disease, but is often used to treat ascites (accumulation of fluid in the peritoneal cavity, which causes abdominal swelling).

Disclaimers

This drug is FDA-approved for human use. However, it is common practice for veterinarians to prescribe such drugs for use in dogs and cats.