Sulfodene Medicated Hot Spot & Itch Relief Spray for Dogs, 8-oz

By Sulfodene
Rated 4.1111 out of 5 stars
$9.45Chewy Price
$12.99Chewy Price
$8.98Autoship Price
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About This Item


  • Medicated spray treats itchy hot spots, insect bites and irritated wounds.
  • Formula includes a blend of antibacterials and pain relievers.
  • Works to reduce scratching and inhibit infection to prevent a skin issue from getting worse.
  • Also contains soothing aloe vera to moisturize the affected area.
  • Spray application allows you to easily spot treat wherever you pal needs the aid.

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Play Video: Learn More About Sulfodene From Our Team of Experts
Learn More About Sulfodene From Our Team of Experts

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Top IngredientsActive Ingredients: Benze Chloride 0.2%, DL-Panthenol 0.05%, Other Ingredients: Deionized Water...Purified Water, Lidocaine Hci, Glycerin...Chlorhexidine Gluconate, Phospholipid Complex, PCMX...Active Ingredients: Pramoxine Hydrochloride 1%, Inactive Ingredients: Purified Water, Oat Flour...Certified Organic Witch Hazel, Certified Organic Aloe Vera Leaf, Certified Organic Vegetable Glycerin...
Health FeatureItch & Redness Remedy, Skin & Coat HealthItch & Redness Remedy, Skin & Coat HealthItch & Redness Remedy, Skin & Coat HealthItch & Redness Remedy
Breed SizeSmall Breeds, Medium Breeds, Large Breeds

Questions & Answers

14 Customer Questions

For everyone that has used this product and had success with it, how many times a day did you spray it on the hot spot/irritated skin?
Answer by ChewyApr 27, 2019
This spray can be used as often as needed for continued relief.

Can you apply this to paws which dog licks constantly?
Answer by ChewyJul 18, 2017
This spray can be applied to the paws, but the dog should be prevented from licking its paws until the spray has dried. This spray is for external use only.

My dog licked the sulfodene i put on her will she get sick?
Answer by ChewySep 13, 2020
We recommend deterring your pet from licking the area for as long as possible, though it is safe if the spray is ingested so long as it is not in excessive amounts.

Is the main (listed first) ingredient vingar. This does not work for me. I like the old formula.
Answer by ChewyFeb 20, 2018
The active ingredients in this product are as follows, and listed: Benzyl alcohol 2%, Lidocaine Hydrochloride 0.5%, Benzalkonium Chloride 0.05%. This product also contains: Water, Hamamelis Virginiana (Witch Hazel) Leaf Extract, Polysorbate 20, Propylene Glycol, Sucrose Octaacetate, Allantoin, Tetrasodium EDTA, Sodium Benzoate, Potassium Sorbate, Diazolidinyl Urea, FD&C Blue No. 1.

ReviewsWrite a Review

Rated 4.1111 out of 5 stars
81 Ratings
Would recommend to a friend

81 Customer Reviews

Rated 1 out of 5 stars
By DC on Aug 8, 2023

Not as strong as it used to be.

Does anyone here remember the Sulfodene that was a yellow liquid? It came in a small bottle and could stop a Labrador from chewing? Well, this isn’t it. This didn’t stop a senior Yorkie girl with allergies from chewing and I am so disappointed! Sulfodene doesn’t seem to sell that yellow liquid anymore, which is a terrible shame. I would have gladly paid three times as much for some that worked. If you’re reading this, keep shopping This is not the Sulfodene you’re looking for.

Rated 4 out of 5 stars
By Ronald on Nov 3, 2023

Medicine ratings

Works great just what I was hoping for

Rated 2 out of 5 stars
By Rick on Apr 17, 2023

Spray bottles terrible

Spray pump doesn’t lift up to spay out of bottle. Have to try to pull up nozzle after first pump. End up just pouring in hand and rubbing on dog.

Rated 1 out of 5 stars
By Sadly on Apr 14, 2023

Leaks everywhere

Good thing they wrap it tightly in plastic for shipping. Even after washed off and dried, the bottle leaks every time I spray it.

Rated 4 out of 5 stars
By sandy on Nov 13, 2022

Helped my dog's hot spots

Bought this because my dog was always scratching her at groin. She was always hot to the touch too, especially in that area. I sprayed this on her and it helped a lot. It is a bit messy because she had chewed all the hair off that area, would help more if it came in a foam maybe but it did help and it quieted that itch down, she wasn't "hot" to the touch anymore. I sprayed her two or three times a day and rubbed it in a bit, then I cut down to once a day and now I don't use it much anymore but will definitely use it again if she starts scratching bad again.

Rated 5 out of 5 stars
By Bailey on May 25, 2022

must have at all times!

We have a pittie mix who has the most sensitive itchy skin and this is the only stuff that gives him so relief!

Rated 5 out of 5 stars
By JCandKatiePie on Nov 19, 2021

A big help!

Katie has always had skin troubles, allergic dermatitis I believe. This Sulfodene is very soothing to her red, itchy inflamed skin.

Rated 5 out of 5 stars
By Alisha on Jun 12, 2020

Actually Works!

This itch spray really does work, my lab has been getting dry skin and this spray has been a huge relief for her.

Rated 5 out of 5 stars
By Precious on Apr 11, 2020

Allergy Help

If your pup licks and chews on self. I would use spray on area(s). Rub in. Then cover or wrap with something so that pup won't remove.

Rated 5 out of 5 stars
By maze on Feb 12, 2020

For skin allergies

My American Bully has skin allergies and this stuff works wonders to calm her skin for at least a couple of hours. The only drawback is that it wears off pretty quickly. However, it smells GOOD and does its job short-term.