Thomas Labs Bio Case Plus Pancreatic Support Powder Dog & Cat Supplement

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Help your furry friend’s digestion with Bio Case Plus Enzyme Therapy Dog & Cat Powder from Thomas Labs. This digestive supplement contains high levels of enzymes, as well as probiotics, bioavailable vitamin B12 and intrinsic factor to help support pets in need of B12 supplementation. It also helps with the absorption of nutrients in your paw-tner’s digestive system, so he gets the nutrients he needs from his food. Easily administered - just sprinkle over your pet's food. Get your playmate back on track with Thomas Labs Bio Case Plus Enzyme Therapy Dog & Cat Powder.

Key Benefits
  • Digestive supplement that supports enzyme replacement needs in dogs and cats.
  • Contains high levels of enzymes to benefit the pancreas.
  • Assists in the digestion of carbohydrates, proteins and fats.
  • Helps the absorption of nutrients in your furry friend’s digestive system.
  • Supports pets in need of B12 supplementation.

See all items by Thomas Labs

  • Item Number
  • Weight
    2.2 pounds
  • Lifestage
  • Breed Size
    Small Breeds, Medium Breeds, Large Breeds, All Breeds
  • Food Form
  • Product Form
Nutritional Info

Dried Porcine Pancreas, Vitamin B12 Supplement, Dried Lactobacillus Acidophilus Fermentation Product, Intrinsic Factor (Porcine Stomach).

Caloric Content

3,389 kcal/kg; 9.49 kcal/scoop

Guaranteed Analysis
Vitamin B121,000 mcg min
Lipase57,000 USP min
Protease407,000 USP min
Alpha-Amylase475,000 USP min
Trypsin453,000 USP min
Lactobacillus Acidphilus1 Billion CFU min
Feeding Instructions

Administer at each meal to dogs or cats over six weeks of age. Add to moistened food (canned or dry).

Dogs: Add 3/4 to 1 scoop per cup of food.

Cats: Add 1/4 to 1/2 scoop per cup of food.

Thorough mixing of the moist food will be necessary to bring the enzymes into close contact with the food particles.

After mixing is complete, incubate at room temperature for 15-20 minutes.

For dogs and cats only. This product is intended for intermittent or supplemental feeding.

Storage Instructions

Store at controlled room temperature; 15C – 30C (59F – 86F).


Why should I include vitamins & supplements in my pet’s diet?

Most commercial pet foods include baseline vitamins and nutrients, but some may not have the adequate amount to suit your pet’s exact health needs. Like in humans, vitamins and supplements can help support your pet’s long-term health, regulating everything from digestion to muscle growth. Consult your veterinarian to determine the best vitamins and supplements for your furry friend.

How often should I give this supplement to my pet?

It is recommended to give the suggested dosage based off your pet’s weight. Please refer to the Feeding Instructions tab and consult with your veterinarian for more information.

Is this supplement safe to use with the medication my pet is currently taking?

If your pet has a medical condition and is taking other medication, we recommend consulting with your veterinarian to ensure that this supplement is safe to use.

My pet is allergic to certain ingredients, will this product be safe to use?

For a complete list of ingredients, click on the 'Nutritional Info' tab, next to the 'Description' tab, just under the product photos. If you are unsure about the safety of this product for your pet, we recommend consulting with your veterinarian.

Does this product come in other product forms?

For a complete assortment of products by the manufacturer of this supplement, click on the link next to the item name at the top of the page. You can also find an assortment of supplements across all product forms on our page.

Rating: 5.0 of 5 stars 9 Reviews 9 Reviews 5 out of 5 Stars

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9 Reviews

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  • 5 out of 5 stars

    Saved my dogs life!

    By Jerily on May 20, 2021

    After about 8 mos of trying to figure out what was wrong with our 10yr old border collie I ran across an article on EPI. The vet hadn’t thought of it because he didn’t really fit the profile. He was down to 25#, I was cooking food for him 2x a day. Talking about end of life. Willing to try everything I ordered a small container just because. Saw results with in 2 days! It’s been 6 weeks, he has regained the weight, his hair coat is looking healthier and he is eating normally. I use a generous scoop morning and night mixed in with his canned/kibble meals. Easy and worth it!!

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  • 5 out of 5 stars

    Great product for dogs with EPI

    By Royinna on Jan 14, 2021

    Our 3 yr old GSD, Logan has been using this product for almost 2yrs now and really helped with his EPI. He is not a picky eater at all. So when we noticed how much he’s lost weight from 110 lbs to 98lbs and had frequent loose stools.., we asked other fur parents and our vet’s advice ~ 8 out of 10 mentioned to use pancreatic enzyme powder and Chewy made it available and affordable .... and our “house wolfie” is back in the game!!! Thanks, Chewy!!

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  • 5 out of 5 stars


    By Ralynn on Dec 14, 2020

    We found out that our German shepherd had EPI when he was about 10 months old. He went from 88 pounds to 65 pounds in just a short period. His body was starving and he was getting very aggressive over food with us. We were told by the vet we would need an enzyme powder so we wanted to find a cheaper product than what they offered. Thank goodness we found Thomas labs powder! It literally saved our dogs life, he wouldn't be here if we didn't have this powder. Our German shepherd has been using this powder since a puppy and he is currently 6.5 years old and it still works.

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  • 5 out of 5 stars

    Worth every penny

    By Zack on Jul 22, 2020

    It has helped our 15 year old dog tremendously with his pancreatitis. We were out of options and this was our last effort to help him. A week after giving him this supplement, he’s the happiest he’s been in years. No more digestive issues and he now has regular and solid stools again. I hope this review helps other dogs and dog owners. Thank you for making this product and thank you Chewy for selling it!

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  • 5 out of 5 stars

    Great for EPI

    By Cindi on Feb 2, 2020

    My little dog has EPI and has been using Bio Case since her diagnosis. We switched to Bio Case Plus and have had no issues. We give her an additional B12 supplement so having it in the enzymes is a great bonus. The ingredients/ratios are comparable to the prescription enzymes, which is another reason why we chose this product. Superb product in my opinion.

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  • 5 out of 5 stars

    Low smell/taste- cat will eat mixed in food

    By Bevha on Jan 21, 2020

    Bio Case Plus is my favorite enzyme for my cat with EPI. The others have a strong taste and smell, I had to syringe the other types into my cat which led to mouth ulcers and lots of stress. This one has almost no taste- he will eat Bio Case Plus mixed in food - this makes my life so much easier and much less stress on me and the cat. The B-12 addition is great. Note that the regular Thomas Labs Bio Case (non Plus) has a strong smell and taste. Not sure why this one is different, but I'm VERY GLAD.

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  • 5 out of 5 stars

    Enzymes saved my dog

    By Mickey on Apr 15, 2020

    Chewy always gets my dog his life saving enzymes quickly and consistently. Love them!

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  • 5 out of 5 stars

    Highly recommend

    By Emily on Dec 25, 2019

    Our shepherd was having digestive issues, going to often & very loose stools plus losing weight. This has been a lifesaver for her & us!!

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  • 5 out of 5 stars

    Great for my EPI dog

    By lizzbee13 on Sep 11, 2019

    Lily has had EPI for over 3 years and this has kept her stable and able to keep on her weight. This is also a great product because it already has the B12 with intrinsic factor in it. Many aren't familiar with EPI and this saved my dogs life

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