Tildren is a prescription medication formulated to help horses control symptoms associated with navicular syndrome. This degenerative condition typically causes pain in the heel of the horse’s front feet, where the navicular bone is located. Horses can experience pain from changes in the bones, tendons, ligaments and bursa—the joint structures that are filled with fluid. This pain can result in lameness, which causes the horse to move abnormally by overcompensating for the affected area. Tildren helps to restore balance to the bone remodeling process, which replaces old bone tissue with new tissue.
Tildren is indicated for the control of clinical signs associated with navicular syndrome in horses. Navicular syndrome is the most common cause of chronic forelimb lameness in performance horses. It is a degenerative process instigated by mechanical forces.
Possible Side Effects
Do not use in horses with impaired renal function or with a history of renal disease. Bisphosphonates are excreted by the kidney; therefore, conditions causing renal impairment may increase plasma bisphosphonate concentrations resulting in an increased risk for adverse reactions. Do not use in horses with known hypersensitivity to tiludronate disodium or to mannitol.
Drug & Food Interactions
NSAIDs should not be used concurrently with Tildren. Concurrent use of NSAIDs with Tildren may increase the risk of renal toxicity and acute renal failure.
NSAIDs should not be used concurrently with Tildren. Concurrent use of NSAIDs with Tildren may increase the risk of renal toxicity and acute renal failure. The safe use of Tildren has not been evaluated in horses less than 4 years of age. Bisphosphonates should not be used in pregnant or lactating mares, or mares intended for breeding.
Patient Information Sheet
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