Tri-Heart Plus Chewable Tablets for Dogs, 26-50 lbs (Green Box), slide 1 of 1

Tri-Heart Plus Chewable Tablets for Dogs, 26-50 lbs, 6 treatments (Green Box)

Prescription Item

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Description

Your furry friend must have a current heartworm test result on file with your veterinarian in order to be prescribed heartworm medication. Please visit your veterinarian to have this test performed annually to protect your four-legged friend. Tri-Heart Plus is an easy-to-feed chewable tablet prescribed to help keep your dog free of heartworm and other dangerous parasites. When given monthly, this simple and palatable tablet helps to protect your pet by killing the larvae before they reach your dog's heart. Best of all, the tasty tablets can be fed just like a treat! Your pet won't even know you're working to protect their heart.

Uses

Tri-Heart Plus is a monthly chew indicated to kill heartworm larvae and to control/treat adult hookworms and roundworms.

Possible Side Effects

Tri-Heart Plus is safe and has caused no side-effects in most dogs, but upset stomachs have been reported. Incoordination, convulsions, or drooling have also been reported rarely. Always contact your veterinarian if your pet appears sick or behaves strangely after taking Tri-Heart Plus.

Drug & Food Interactions

Talk to your veterinarian about any other drugs your dog is taking before starting Tri-Heart Plus.

Precautions

All dogs should be tested for existing heartworm infection before starting treatment with Tri-Heart Plus, which is not effective against adult D. immitis. Infected dogs must be treated to remove adult heartworms and microfilariae before initiating a program. Tri-Heart Plus is not indicated for dogs younger than 6 weeks old. Herding breeds (such as Collies) can be sensitive to the active ingredient, so talk to your veterinarian if your dog may be affected. If you miss a dose, your dog needs a blood test to resume your normal doses safely. Notify your veterinarian if you've skipped a dose or have any concerns. Keep this and all drugs out of the reach of children.

This item is excluded from the first-time Autoship promotion.

Dosage Chart

Color on BoxWeight RangeStrengthDosageProduct Page
BlueUp to 25 lbs68 mcg Ivermectin & 57 mg PyrantelAdminister orally once a month✓-Click Here
Green26-50 lbs136 mcg Ivermectin & 114 mg PyrantelAdminister orally once a month✓-Click Here
Brown51-100 lbs272 mcg Ivermectin & 227 mg PyrantelAdminister orally once a month✓-Click Here
  1. Prescribing Information

See all items by Tri-Heart Plus

  • Item Number
    146099
  • Common Brand Name(s)
    Tri-Heart Plus, Heartgard Plus
  • For Use With
    Dogs
  • Generic Name
    Ivermectin, Pyrantel Pamoate
  • Administration Form
    Oral
  • Brand
    Merck
  • Lifestage
    Adult, Senior, Puppy
  • Breed Size
    Medium Breeds
  • Product Form
    Chewable Tablet
  • Strength
    136 mcg Ivermectin and 114 mg Pyrantel
  • Health Condition
    Heartworms, Hookworms, Roundworms
  • Drug Type
    Parasiticide
Ingredients
Ingredients

Active Ingredients: 136 mcg Ivermectin and 114 mg Pyrantel.

Instructions
Recommended Dosage

1 chew

Storage Instructions

Store at controlled room temperature of 59° - 86°F. Protect product from light.

FAQ

Is Tri-Heart Plus safe for my dog?

Tri-Heart Plus flavored chewable tablets are an FDA-licensed product, indicating they are safe and effective when used as recommended on the label. All dogs should be tested for existing heartworm infection before starting treatment with Tri-Heart Plus.

My dog is taking some other medications for another condition. Is it still safe to give her Tri-Heart Plus tablets?

In clinical trials, many commonly used flea collars, dips, shampoos, anthelmintics (deworming medications), antibiotics, vaccines and steroid preparations have been administered with ivermectin/pyrantel in a heartworm disease prevention program. For questions about specific medications, please consult your veterinarian.

Is it okay to give my pregnant dog Tri-Heart Plus tablets? What about after she has given birth and is breastfeeding the puppies?

Ivermectin/pyrantel, the active ingredients in Tri-Heart Plus, have a wide margin of safety at the recommended dose level in dogs, including pregnant females, breeding males and females, and puppies 6 weeks or older, according to the package insert.

Can Tri-Heart Plus tablets be given to a dog that has heartworms or that is heartworm-positive?

No. Tri-Heart Plus is labeled for use in dogs to prevent heartworm disease and not for the treatment of heartworm infections. The package insert contains this precautionary statement: “Infected dogs must be treated to remove adult heartworms and microfilariae before initiating a program with Tri-Heart Plus flavored chewable tablets.”

Can Tri-Heart Plus be used as a heartworm preventive in cats?

No. Tri-Heart Plus is not approved for use in cats.

Our dog's Tri-Heart Plus flavored chewable tablets expired last month. Is it still okay to give her Tri-Heart Plus tablets after their expiration date?

Medications, including Tri-Heart Plus, should never be administered after the expiration date. Studies have shown that Tri-Heart Plus will maintain its desired effectiveness when administered prior to the expiration date, when stored as recommended on the label.

My dog weighs less than 10 lbs. Should I give him the whole tablet even though it says for dogs up to 25 lbs?

Yes. The entire tablet should be administered as a single dose once each month. The smallest-sized Tri-Heart Plus tablet, in the blue-colored packaging, is labeled for dogs weighing 25 lbs or less. These tablets are scored to make it easier to break the tablet apart and have the small dog take the complete tablet but in smaller pieces at a time. Regardless of whether the tablet is broken apart or given the whole, the entire tablet should be given as a single dose.

Is it okay to give my pregnant dog Tri-Heart Plus tablets? What about after she has given birth and is breastfeeding the puppies?

Ivermectin/Pyrantel, the active ingredients in Tri-Heart Plus, have a wide margin of safety at the recommended dose level in dogs, including pregnant females, breeding males and females, and puppies 6 weeks old or more according to the package insert.

I accidentally gave my dog his Tri-Heart Plus tablet after my husband had already given one to him. Will he be okay?

Contact your veterinarian immediately if accidental overdose occurs. To reduce the risk of accidental overdose in situations where more than one person may administer Tri-Heart Plus, we suggest ticking off the date on a specially marked calendar or making some other note to indicate that the dose has been given. Make a habit of checking with the other pet caregivers in your household before giving any medications to your pet.

My dog is taking some other medications for another condition. Is it still safe to give her Tri-Heart Plus tablets?

In clinical trials, many commonly used flea collars, dips, shampoos, anthelmintics (deworming medications), antibiotics, vaccines, and steroid preparations have been administered with ivermectin/pyrantel in a heartworm disease preventive program. For questions on specific medications, please consult with your veterinarian.

I forgot to give my dog his Tri-Heart Plus medication last month. Is he still protected? What should I do?

If the interval between doses exceeds 30 days, the efficacy of ivermectin can be reduced. Therefore, for optimal performance, the chewable tablet must be given once a month, on or about the same day of the month (Sign up for our email reminder service). If treatment is delayed, whether by a few days or many, please contact your veterinarian, as immediate treatment with Tri-Heart Plus chewable tablets and resumption of the recommended dosing regimen minimizes the opportunity for the development of adult heartworms.

Where can I buy Tri-Heart Plus tablets?

Tri-Heart Plus flavored chewable tablets can be obtained by prescription only and are available from your veterinarian.

Is Tri-Heart Plus safe for my dog?

Tri-Heart Plus flavored chewable tablets are an FDA-licensed product, indicating that they are safe and effective when used as recommended on the label. All dogs should be tested for existing heartworm infection before starting treatment with Tri-Heart Plus.

How long will the Tri-Heart Plus tablets last once removed from the blister pack?

The blister package is designed to protect the tablets from exposure to air and light. Therefore a tablet should be administered at the time it is removed from the blister foil. Also if the blister or foil is not intact (for example the foil is peeled back or there's a hole in it), the tablet should not be used.

Do Tri-Heart Plus tablets contain wheat or rice gluten?

No.

Where can I find additional information about heartworms?

The American Heartworm Society (AHS) is an excellent source of information for both pet owners and veterinarians.

Rating: 4.8 of 5 stars 91 Reviews 91 Reviews 4.8 out of 5 Stars

99% Recommend

99% of reviewersrecommend this product

Rating: 4.8 of 5 stars 4.8 / 5

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91 Reviews

Showing 1-10 of 91 Reviews

  • 5 out of 5 stars

    Works great

    By on

    Love that there's a more affordable option for these pills, these are great. My dog thinks it's a treat and chews it right up! They are incredibly hard to break into smaller pieces just beware! I'm lucky my dog chews...

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  • 5 out of 5 stars

    Love the delivery

    By on

    This is the heartworm medication my vet has been prescribing to my dog. It's a good product. The price at Chewy is the same as my vets office. I liked ordering from Chewy because of the delivery. Especially during covid it's nice to have items delivered to save you a trip out of the house.

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  • 5 out of 5 stars

    Very impressed

    By on

    This is the first time my dog will be on heartworm medication I just gave him his first pill. I ordered this brand due to all the good reviews, so I'm sure my dog will do just fine. However I want to say how impressed I am with the shipping time I ordered 6/24 my vet approved it the 25th and TODAY I ALREADY HAVE MY PACKAGE.6/26. I will start shopping chewy.com

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  • 5 out of 5 stars

    My dog loves it like a treat.

    By on

    The previous heart worm medication my dog would not eat no matter how I disguised it! My dog would refuse to eat the previous medication and even when I cut it up into tiny pieces and smothered in peanut butter and hid in cheese he would eat around the tiny pieces of his pr vipus medication and leave them. He loves Tri- Heart Plus and it is half the cost of most heart worm medications!

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  • 5 out of 5 stars

    Great price for necessary medicine

    By on

    Our vet says generic Heartgard is okay, brand name not necessary. Great to hear, helps keep prices down and my fur baby healthy.

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  • 4 out of 5 stars

    Looking to save a little?

    By on Top 250 Contributor

    I have come back to Tri-Heart Plus after using a more inclusive name brand after being furloughed and still love this product. Never had a dog get heart worms while on this product and never had any negative reactions to it. A solid staple in Heartworm preventatives. The downside to this is it’s a hard pill and not very appetizing to the pups but this is an extremely easy fix with a can of wet dog food or pumpkin. We crush it with a spoon and mix it up and viola! Dogs are happy and I’m happy. The one other downside is there’s no tapeworm protection, but it does kill roundworms. Still extremely satisfied with this product. Less money, same protection, happy family.

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  • 5 out of 5 stars

    Good Product for my delicate gut dog.

    By on

    I started using this product a year ago for our 10 year old labradoodle who has a very finicky intestinal problem. He is doing very well with this product. He likes to eat the tablet which is a good thing with him, because he can be stubborn if he knows it's a pill or a medication.

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  • 3 out of 5 stars

    Took too long to ship

    By on

    They are slow Allow 3-4 weeks for delivery _zzzzzzzzzzzzz..... Must be asleep there

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  • 5 out of 5 stars

    Easy and as advertised

    By on

    This process was simple. Only thing we had to do on our end was call the vet. The pills arrived about five days later.

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  • 5 out of 5 stars

    Been using for 15 years!

    By on

    Tri Heart has been my go to HW preventative for my dogs for 15 years. My Beagle and Dalmatian that passed away last year were both on it their entire lives and now my new pup is on it for his. Thanks Tri Heart for keeping my babies safe!

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