Ursodiol (Generic) Capsules, slide 1 of 1

Ursodiol (Generic) Capsules, 300-mg, 1 capsule

Prescription Item

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Ursodiol is a prescription medication given to treat certain diseases of the liver and gallbladder, including chronic hepatitis. It may also be used to help remove gallstones that contain cholesterol. Customers may receive this drug under the names Actigall, Urso.


Ursodiol is used to treat certain diseases of the liver and gallbladder by reducing the amount of cholesterol in bile and bile stones.

Possible Side Effects

Please contact your vet immediately if you notice any of the following: allergic reaction, diarrhea, vomiting, depression or jaundice (yellowing of the gums, skin or eyes). Other side effects are possible. If your animal seems ill in any other way while taking Ursodiol, contact your veterinarian immediately.

Drug & Food Interactions

Notify your veterinarian of any other medications, including vitamins and supplements, your pet is taking before using this medication.


Do not give Ursodiol to pets who are allergic to it or similar medications. Caution should be used in animals with complications of gallstones, such as pancreatitis, bile duct obstruction or inflammation of the gallbladder or bile ducts (cholecystitis and cholangitis). These animals should only take Ursodiol if the benefits outweigh the risks. If you observe any unusual signs in your pet, contact your veterinarian immediately.

This drug is FDA-approved for human use. However, it is common practice for veterinarians to prescribe such drugs for use in dogs and cats.

NOTE: For Generic Medications, picture displayed may not depict actual product. Generic medications may vary from one order to the next by size, color and shape depending on manufacturer.

  1. Prescribing Information

See all items by Ursodiol

  • Item Number
  • Generic Name
  • Common Brand Name(s)
    Actigall, Urso
  • For Use With
    Dogs & Cats
  • Administration Form
  • Product Form
  • Health Condition
    Liver Disease
  • Drug Type
    Bile Acid


Recommended Dosage

Use as directed by your veterinarian.

Storage Instructions

Store at temperatures between 68° - 77°F.


What is Ursodiol?

This is an oral capsule that is used to treat diseases of the liver and gallbladder when used as directed by your veterinarian. It may also be used to help remove gallstones that contain cholesterol.

What are the benefits of Ursodiol?

  • Usually well tolerated
  • Helps to treat certain diseases of the liver and gallbladder including chronic hepatitis
  • Can reduce the absorption of cholesterol and increase the breakdown of cholesterol

How is this medication given?

Give Ursodiol only as directed by your veterinarian. Capsules should be given by mouth preferably with food. If you do not understand how to give Ursodiol properly, always consult with your veterinarian.

How does this medication work?

Ursodiol works by improving the flow of bile into and out of the gallbladder and into the intestine. This prevents bile from building up. If bile builds up, it can be potentially toxic. This medication can also help decrease cholesterol in the bile by reducing production of it in the liver. Ursodiol can also reduce the amount of cholesterol absorbed from food and increases its breakdown which can be especially helpful in removing gallstones that are made if cholesterol.

What results can I expect?

It can take weeks to months of using Ursodiol in your pet to see improvement in clinical symptoms and lab work.

Rating: 2.1 of 5 stars 6 Reviews 6 Reviews 2.2 out of 5 Stars

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67% Recommend

67% of reviewersrecommend this product

Rating: 2.1 of 5 stars 2.2 / 5

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6 Reviews

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  • 2 out of 5 stars

    Hoping For Smaller Dosage

    By on

    Adding my request for a smaller dosage of this medication. My fur baby needs a 75mg dose and capsules are very difficult to work with. Please consider our requests for tablets and smaller mg dosages.

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  • 1 out of 5 stars

    Still waiting for a lower dose tablet form instead of capsule

    By on

    I love Chewy and wish I could just transfer my entire prescription list here. But for this medication my fur baby needs 50 mg...so 300mg in a powder capsule form isn't gonna cut it. Let's get the splittable tablet form in already Chewy, that would be great!

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  • 2 out of 5 stars

    Need tablets

    By on

    I also wish this came in tablet form. My dog currently gets a 250mg tablet from our vet and he only gets 1/2 tablet daily.

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  • 3 out of 5 stars

    Too large a dose

    By on

    I also need this a smaller dose, 60mg and am having to pay extra to have it compounded to a smaller dose. It would be helpful and more beneficial if you could buy it this way.

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  • 4 out of 5 stars

    So Glad You Carry This Medication

    By on

    A few months ago I left a one star review for this product, because it did not come in a tablet form in order to divide it to get to the 75 mg that my dog needs. Someone from Chewy called me less than an hour later to personally tell me they were working on getting more options for this drug. That is great customer service, and I feel confident and hopeful that they will have it as soon as they can get it. It would certainly make my life easier, because I am currently having to have it custom made at a compounding pharmacy.

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  • 1 out of 5 stars

    This is not a practical type of pill

    By on

    This medication also comes in tablet form which is needed for any smaller dog since it is often prescribed as 1/2 or 1/4 tablets dosages. Obviously, cannot cut a capsule. Chewy- please get the tablet version of this medication! Thank you.

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